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New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research has found some compounds effective in blocking the proliferation of certain bacteria, raising hopes of a new class of drugs to combat antibiotic resistant infections

13 Mar 2014

AAOHN, ACOEM collaborate to study workplace health and safety issues linked with use of marijuana

The American Association of Occupational Health Nurses (AAOHN) and the American College of Occupational and Environmental Medicine (ACOEM) have announced they will collaborate to study workplace health and safety issues associated with worker impairment from the use of marijuana and other drugs.

11 Mar 2014

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Promethera Biosciences, a company that develops innovative therapies for the treatment of liver diseases, today announces a collaboration with EMD Millipore to develop an improved ready-to-use microfluidic perfusion liver assay. This new product is designed to perform more robust studies in pre-clinical toxicity and drug metabolism.

11 Mar 2014

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

Homologous recombination is a technology that enables the targeted insertion of nucleotide fragments into the genome of a cell. It is called ‘homologous’ because it uses a sequence that is a homologue to the sequence being targeted in a gene, so that the sequence is recognized.

10 Mar 2014

A pill may provide hope to relapsed leukemia and lymphoma patients

A pill that suppresses a key regulator of cancer growth may provide hope to relapsed leukemia and lymphoma patients running out of treatment options for their aggressive, treatment-resistant disease, according to three reports published online today in Blood, the journal of the American Society of Hematology.

10 Mar 2014

Tubulin protein is a well-validated cancer drug target

Tubulin, the building-block protein of cellular microtubules, is a well-validated cancer drug target: Disrupting tubulin polymerization affects cytoskeletal function and thus cell division.

10 Mar 2014

Fibrotech successfully completes Phase Ia trial of anti-fibrotic compound FT011

Fibrotech, an Australian biopharmaceutical company developing a new class of drugs to prevent a massive health burden associated with fibrosis, today announced that its lead anti-fibrotic compound FT011 has successfully completed a Phase Ia trial in healthy volunteers demonstrating safety and tolerability up to doses of 1000mg.

10 Mar 2014

Study to understand how bisphenol-A may promote breast cancer growth

UT Arlington biochemists say their newly published study brings researchers a step closer to understanding how the commonly used synthetic compound bisphenol-A, or BPA, may promote breast cancer growth.

6 Mar 2014

Boehringer Ingelheim reports results from SVR12 Phase 3 trial in patients with HCV/HIV co-infection

Today Boehringer Ingelheim announced results from STARTVerso4 in patients with HCV/HIV co-infection. Hepatitis C viral cure 12 weeks after the conclusion of treatment (SVR12) was achieved by 72% of all patients in the trial. Patients were enrolled in either 120mg or 240mg faldaprevir dose groups.

6 Mar 2014

Tetraphase Pharmaceuticals reports net loss of $11.3 million for Q4 2013

Tetraphase Pharmaceuticals, Inc. today reported financial results for the quarter and full year ended December 31, 2013.

6 Mar 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Safeguard Scientifics, Inc. today announced fourth quarter and full-year 2013 financial results. For the three months ended December 31, 2013, Safeguard's net income was $24.0 million, or $1.10 per share, compared to net loss of $10.8 million, or $0.51 per share for the same period in 2012. For the year ended December 31, 2013, Safeguard's net loss was $35.5 million, or $1.66 per share, compared to $39.4 million, or $1.88 per share for the same period in 2012.

6 Mar 2014

Research to identify exact mechanisms behind preterm birth and fetal brain injury

An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins-led research suggests.

6 Mar 2014

New drug is effective against superbug MRSA

"I routinely call hospitals and request their yearly antibiotic susceptibility testing data," said Washington University in St. Louis' Timothy Wencewicz. "The log might say, for example, that they've treated hundreds of patients for Acinetobacter baumanni, a bacterium brought into U.S. hospitals by soldiers wounded in the Iraq war, with 30 different antibiotics.

6 Mar 2014

Beer hop leaves could be used to battle cavities and gum disease, say scientists

Beer drinkers know that hops are what gives the drink its bitterness and aroma. Recently, scientists reported that the part of hops that isn't used for making beer contains healthful antioxidants and could be used to battle cavities and gum disease. In a new study in ACS' Journal of Agricultural and Food Chemistry, they say that they've identified some of the substances that could be responsible for these healthful effects.

6 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

Study: 55% of women are passive smokers due to exposure to tobacco smoke

As shown in a study carried out by researchers at 13 research centres in Asturias, Gipuzkoa, Sabadell and Valencia, over half of non-smoking pregnant women, 55%, are passive smokers.

5 Mar 2014

Plant pigment could prevent damage to nerves linked with childhood form of SMA

The research team have found that a plant pigment called quercetin - present in some fruits, vegetables, herbs and grains - could help to prevent damage to the nerves associated with the childhood form of motor neurone disease, spinal muscular atrophy (SMA).

5 Mar 2014

New probes help to quantify normally folded and misfolded conformations of protein in cells

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

5 Mar 2014

Bruker announces next generation JuiceScreener™ 3.0

At Pittcon 2014, Bruker today announced the third release of its successful NMR JuiceScreenerTM. The new release comes with significant enhancements that enable the accurate, swift, automated screening of even more fruit juice types from just a single experiment.

4 Mar 2014

Rigel Pharmaceuticals reports net loss of $16.9 million for fourth quarter 2013

Rigel Pharmaceuticals, Inc. today reported financial results for the fourth quarter and year ended December 31, 2013.

4 Mar 2014

Compound News and Research

New research raises hopes of new class of drugs to combat antibiotic resistant infections

AAOHN, ACOEM collaborate to study workplace health and safety issues linked with use of marijuana

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

A pill may provide hope to relapsed leukemia and lymphoma patients

Tubulin protein is a well-validated cancer drug target

Fibrotech successfully completes Phase Ia trial of anti-fibrotic compound FT011

Study to understand how bisphenol-A may promote breast cancer growth

Boehringer Ingelheim reports results from SVR12 Phase 3 trial in patients with HCV/HIV co-infection

Tetraphase Pharmaceuticals reports net loss of $11.3 million for Q4 2013

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Research to identify exact mechanisms behind preterm birth and fetal brain injury

New drug is effective against superbug MRSA

Beer hop leaves could be used to battle cavities and gum disease, say scientists

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Study: 55% of women are passive smokers due to exposure to tobacco smoke

Plant pigment could prevent damage to nerves linked with childhood form of SMA

New probes help to quantify normally folded and misfolded conformations of protein in cells

Bruker announces next generation JuiceScreener™ 3.0

Rigel Pharmaceuticals reports net loss of $16.9 million for fourth quarter 2013

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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