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Study links Western diet to chronic inflammation and colorectal cancer growth

Colorectal cancer, the second leading cause of cancer-related deaths in the United States, may be fueled by the food on our plates.

10 Dec 2024

Geriatric Surgery Verification program enhances postoperative outcomes for older cancer patients

Implementing the American College of Surgeons (ACS) Geriatric Surgery Verification (GSV) program leads to better postoperative outcomes and preserves independence in older cancer patients undergoing major abdominal procedures, according to a new study published in the Journal of the American College of Surgeons

10 Dec 2024

Scientists identify potential therapeutic targets for diabetic kidney disease

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

10 Dec 2024

Alcohol and substance use contribute to rising e-scooter and e-bike injuries

The numbers of e-scooter and e-bike injuries have tripled in the US since 2019, fuelled by alcohol and substance use, finds a nationwide analysis of emergency department visits, published online in the journal Injury Prevention.

10 Dec 2024

New advances offer hope for patients with systemic mastocytosis

Dana-Farber Cancer Institute researchers are breaking new ground in the fight against systemic mastocytosis, a rare and heterogeneous condition that is often challenging for clinicians to accurately diagnose and treat.

9 Dec 2024

Researchers identify key mechanisms behind heart disease in type 2 diabetes

People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis.

9 Dec 2024

Novel drug combination shows promise for CLL treatment

A novel, fixed-duration drug combination - consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax), with or without a third blood cancer drug - shows deep and durable responses in patients with chronic lymphocytic leukemia (CLL), Dana-Farber Cancer Institute investigator Jennifer Brown, MD, PhD, reports at the 66th American Society for Hematology (ASH) Annual Meeting and Exposition, on behalf of the trial investigators.

9 Dec 2024

Lab-grown tumor organoids predict patient response to CAR T cell therapy

For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time.

9 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

CHOP study shows safety of rotavirus vaccine in neonatal intensive care unit

Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks.

9 Dec 2024

Simple dietary supplement may provide new approach to boost CAR T cell cancer-fighting power

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

9 Dec 2024

Hospital-acquired pressure ulcers may hinder neurological recovery in spinal cord injury patients

Research led by The Ohio State University Wexner Medical Center and College of Medicine along with scientists at the Charité – Universitätsmedizin Berlin in Berlin, Germany, provides first evidence that hospital-acquired pressure ulcers are a potent risk factor for poor neurological recovery among patients with acute spinal cord injury (SCI).

9 Dec 2024

Breakthrough treatment improves survival rates for children with B-ALL

Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children.

9 Dec 2024

Two studies show potential for newborn genetic screening

Two studies published today in the American Journal of Human Genetics show the potential for genomic screening in newborns to address high rates of infant hospitalization and mortality in the United States.

9 Dec 2024

Study: Closing underperforming hospitals may exacerbate health inequalities in rural areas

Closing underperforming hospitals may do more harm than good, particularly in rural areas -regardless of their performance status, according to new research from the University of Surrey.

9 Dec 2024

Vanderbilt University Medical Center receives $7 million to study breathing tube size in critical care

Vanderbilt University Medical Center has been approved for $7 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to study the effect of breathing tube size on breathing, speaking and swallowing after critical illness.

6 Dec 2024

$1.5 million grant supports alternatives to opioids initiative at University Hospitals

A grant of nearly $1.5 million from the Department of Health and Human Services through its Substance Abuse and Mental Health Services Administration (SAMHSA) will enable University Hospitals Cleveland Medical Center to develop and implement an Alternatives to Opioids (ALTO) program within its Emergency Department (ED).

6 Dec 2024

New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

Asylum seekers in the U. S. report high levels of stress and cardiovascular disease symptoms

Many individuals seeking asylum in the United States show increased stress and pain symptoms that are associated with indications of cardiovascular disease, according to Weill Cornell Medicine researchers.

6 Dec 2024