Pathogen News and Research

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Potential new way to vaccinate against avian flu

Researchers at the University of Pennsylvania School of Medicine have identified a potential new way to vaccinate against avian flu. By delivering vaccine via DNA constructed to build antigens against flu, along with a minute electric pulse, researchers have immunized experimental animals against various strains of the virus.

1 Jul 2008

Increasing number of severe bone infections, health complications in children linked to MRSA

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) as a major pathogen has led to more complications and longer hospital stays for children with acute bone infections, UT Southwestern Medical Center researchers report

30 Jun 2008

Viruses hitch a ride in the cell

Viruses can travel around cells they infect by hitching a ride on a microscopic transport system, according to new research. Cells are exposed to foreign DNA and RNA and it is understood that some of this genetic material can be integrated into the host genome. Using modern microscopic techniques, scientists have been able to see how virus DNA is transported in the cell.

23 Jun 2008

New pathogen from pigs' stomach ulcers

Scientists have isolated a new bacterium in pigs' stomachs thanks to a pioneering technique, offering hope of new treatments to people who suffer with stomach ulcers, according to research published in the June issue of the International Journal of Systematic and Evolutionary Microbiology.

8 Jun 2008

A genetic tool for cleaner water

A genetic tool used by medical researchers may also be used in a novel approach to remove harmful microbes and viruses from drinking water.

3 Jun 2008

New research into superbug Clostridium difficile

New research into the toxins, virulence, spread and prevention of the superbug Clostridium difficile is reported in the June special issue of the Journal of Medical Microbiology. These findings will play a crucial role in providing us with ammunition in the fight against a sometimes deadly pathogen.

1 Jun 2008

Discovery on how an Helicobacter pylori toxin gets into cells

Helicobacter pylori is one tough bug. It can survive in the human stomach, a zone with a pH somewhere between that of lemon juice and battery acid. Now researchers have discovered how an H. pylori toxin gets into cells, a feat that helps the bacterium live in one of the most inhospitable environments in the body

26 May 2008

The emerging role of infection in Alzheimer’s

A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis. The realization that pathogens can produce slowly progressive chronic diseases has opened new lines of research into Alzheimer's disease.

25 May 2008

Mayo Clinic research shows U.S. intensive care units' prevention of pneumonia in critically-ill generally strong; identifies area of improvement

Mayo Clinic researchers found that the frequency with which critically-ill patients developed ventilator-associated pneumonia (VAP) is approximately the same at a multidisciplinary medical center such as Mayo Clinic compared to the average VAP-risk rate for 211 hospitals in the National Healthcare Safety Network (NHSN).

20 May 2008

Warning about lack of attention given to hepatitis

A report by the World Hepatitis Alliance has called for an increased focus on hepatitis and says the disease should be given the same attention as AIDS, tuberculosis and malaria.

20 May 2008

Ashwell receptor plays key role in reducing coagulation abnormalities during infection and sepsis

In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is critical in helping the body fight off the abnormal and lethal blood clotting caused by bacterial infection.

19 May 2008

Bacterial slime helps cause Leptospirosis

Leptospirosis is a serious but neglected emerging disease that infects humans through contaminated water. Now research published in the May issue of the journal Microbiology shows for the first time how bacteria that cause the disease survive in the environment.

19 May 2008

New theory suggests how hepatitis C may cause rare immune disease

Of the hepatitis alphabet, the C variant may be the nastiest. In 1990, researchers observed that most patients with hepatitis C also develop a rare autoimmune disease called mixed cryoglobulinemia, a condition that frequently leads to cancer, arthritis or both.

10 May 2008

Better understanding of immune response to HIV infection

The "exhaustion" of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells.

6 May 2008

Newly identified protein called BILBO1 fatal to Trypanosoma brucei

Trypanosoma brucei is a pathogen that causes epidemics of human and animal sleeping sickness in central and Southern Africa, a disease that is fatal if untreated. A new paper published this week in the open-access journal PLoS Biology investigates the formation of a trypanosome structure called the Flagellar Pocket (FP).

6 May 2008

Study explains why steroid therapy for sinusitis and asthma loses its punch over time

Scientists at Johns Hopkins have outlined a new path for potential therapies to combat inflammation associated with sinusitis and asthma based on a new understanding of the body's earliest immune response in the nose and sinus cavities.

29 Apr 2008

Researchers identify Heme detoxification protein - potential target for developing new malaria drugs

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified Heme Detoxification Protein (HDP), a unique protein encoded in the malaria genome that represents a potential target for developing new malaria drugs.

24 Apr 2008

Protein HtpG signals healthier teeth and gums

Antibodies present in people with good oral health could become the first tool for dental professionals to assess a patient's probable response to periodontal disease treatments, say researchers at the University of Michigan.

23 Apr 2008

Red colobus monkeys in Uganda found to harbor antibodies to an unknown orthopoxvirus

Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox. Most of the monkeys screened harbor antibodies to a virus that is similar - but not identical - to known orthopoxviruses.

22 Apr 2008

Monkey malaria - the next bird flu?

An expert at the NIH has highlighted the threat of an emergent highly virulent form of malaria, questioning whether the disease has made the jump from animal to man.

22 Apr 2008