immunity News and Research

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To stoke rural vaccination rates, trusted farmers are asked to spread word

When he became eligible for the coronavirus vaccine in Illinois, Tom Arnold, 68, said he didn’t need any convincing. He raises cattle, hogs and chickens in Elizabeth, a small town in the state's northwestern corner.

19 Aug 2021

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

All COVID-19 vaccines appear less effective when faced with variants such as Delta, according to a new medRxiv* study. However, the researchers suggest that booster shots may help improve immunity and protect against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

18 Aug 2021

Vaccine nationalism may increase COVID-19 case numbers and the emergence of novel variants

The allocation of COVID-19 vaccine between countries has thus far tended toward vaccine nationalism, wherein countries stockpile vaccines to prioritize access for their citizenry over equitable vaccine sharing.

18 Aug 2021

Videos capture the inexorable spread of SARS-CoV-2 in live animals

Video images capture for the first time in live animals the inexorable spread of the COVID-19 virus, tracking the infection as it moved from the noses of mice to the lungs and other organs over the course of six days, in a new study led by researchers at Yale and Université de Montréal.

18 Aug 2021

The White House says boosters for all. Here’s what you need to know.

The Biden administration announced plans Wednesday to offer boosters to all U.S. adults as soon as next month, saying that recent data, including some made available only in the past few days, played a role in that decision.

18 Aug 2021

Why have COVID-19 caseloads been comparatively low in Africa?

A new study has been published in the International Journal of Environmental Research and Public Health that highlights the potential lessons that the world can draw from Africa on assumptions concerning viral pandemics. This is particularly important, given Africa’s long experience with dangerous infectious diseases.

18 Aug 2021

Study examines the prevalence of SARS-CoV-2 antibodies in Geneva, Switzerland

In a paper uploaded to the preprint server medRxiv*, antibodies against both the spike protein and nucleocapsid proteins of SARS-CoV-2 are measured in over 3,000 volunteers, six months following the initiation of the vaccination scheme in Geneva, Switzerland.

18 Aug 2021

Rush to boosters sparks confusion, differing recommendations

When the Food and Drug Administration announced last week that a third dose of Moderna or Pfizer-BioNTech covid-19 vaccine may boost the immunity of some people who are immunocompromised, officials repeated their stance that fully vaccinated, healthy people do not need another dose.

18 Aug 2021

SARS-CoV-2 Delta variant: A gloomy forecast for the United States

The emergence of the Delta variant (B.1.617.2) in the United States has backtracked many plans to return to a pre-COVID era. A surge in COVID-19 cases due to the Delta variant has caused a rise in COVID-19 deaths and hospitalizations after what was previously a steady decline during the summer.

18 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Naive B cells could be useful for predicting vaccination response in immunocompromised

A recent study conducted at the Medical University of Graz, Austria, has revealed that the number of naïve B cells in the blood could independently predict the magnitude of immune response induced by coronavirus disease 2019 (COVID-19) vaccines in immunocompromised patients. The study is currently available on the medRxiv* preprint server.

17 Aug 2021

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.

17 Aug 2021

Study explores the role of nasal bacteria and provides clues to developing better flu, COVID-19 vaccines

While gut microbiota play a critical role in the induction of adaptive immune responses to influenza virus infection, the role of nasal bacteria in the induction of virus-specific adaptive immunity is less clear.

17 Aug 2021

New rapid test for understanding immunity against COVID-19

Electronics specialist Mantracourt has helped engineer a new rapid test which will tell people whether they have immunity against coronavirus and whether that immunity comes from developing antibodies after infection or the vaccine.

17 Aug 2021

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Now, a new study posted to the bioRxiv* preprint server focuses on functional immune memory to SARS-CoV-2, up to nine months in a Southeast Asian cohort, in the absence of re-infection.

16 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

In a recent study, a group of researchers determined the degree to which Pango lineages are distinguishable using spike-only nucleotide sequences.

16 Aug 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

Obtained SARS-CoV-2 immunity, naturally or via vaccination persists 12 months

In a research paper recently uploaded to the preprint server medRxiv* by Havervall et al. (August 12th, 2021), neutralizing antibody titers towards wild-type SARS-CoV-2 and several variants of concern in individuals having either been vaccinated or infected with mild COVID-19 one year earlier are assessed, finding a reduced neutralization capacity against some strains.

16 Aug 2021

immunity News and Research

To stoke rural vaccination rates, trusted farmers are asked to spread word

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

Vaccine nationalism may increase COVID-19 case numbers and the emergence of novel variants

Videos capture the inexorable spread of SARS-CoV-2 in live animals

The White House says boosters for all. Here’s what you need to know.

Why have COVID-19 caseloads been comparatively low in Africa?

Study examines the prevalence of SARS-CoV-2 antibodies in Geneva, Switzerland

Rush to boosters sparks confusion, differing recommendations

SARS-CoV-2 Delta variant: A gloomy forecast for the United States

New bioengineered lung model could help scientists to advance research in lung conditions

Naive B cells could be useful for predicting vaccination response in immunocompromised

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Study explores the role of nasal bacteria and provides clues to developing better flu, COVID-19 vaccines

New rapid test for understanding immunity against COVID-19

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Obtained SARS-CoV-2 immunity, naturally or via vaccination persists 12 months

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