Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

Celiac disease may be caused by gastrointestinal infection in childhood

A new study has found that a childhood stomach bug may be the cause of celiac disease later in life. The findings could pave the way for a vaccine to protect against the disease.

15 Feb 2019

An engineered virus selectively targets and kills cancer cells

An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers.

29 Jan 2019

Duke-NUS researchers highlight possible role of bioaerosol sampling in pandemic surveillance

As a leading global city with a high population density, Singapore is vulnerable to the introduction of biological threats. Initiating an early emergency response to such threats calls for the rapid identification of the causative agent.

6 Dec 2018

Four mild forms of adenovirus cases at Voorhees Pediatric Facility under control and no new cases reported

Voorhees Pediatric Facility, a pediatric special care nursing facility located in Voorhees, New Jersey, has had four patients with chronic lung disease contract a mild form of adenovirus.

2 Nov 2018

WRAIR clinical study evaluates safety and immunogenicity of Marburg vaccine

The Walter Reed Army Institute of Research this week administered the first vaccine in a Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy adult volunteers.

15 Oct 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Easy and rapid test for viral infections can cut antibiotic use, hospitalizations

A quick and easy test for viral infections can reduce unnecessary antibiotic use and hospital admissions, according to new research presented to the European Respiratory Society International Congress today.

17 Sep 2018

Discovering Prion-like Proteins in Eukaryotic Viruses

Dr. George Tetz discusses the discovery of prion-like domains in eukaryotic viruses, and the implications of this study on gene therapies and common neurological diseases such as Alzheimer's Disease.

6 Sep 2018

Airport security trays carry more microbes than toilet seats

A team of researchers from Finland and Britain have shown that over half of all the trays or security bins that the airport authorities use at the security clearance areas carry viruses that can cause respiratory infections.

6 Sep 2018

Mechanical properties of viral DNA influence the course of infection, study finds

A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said.

5 Sep 2018

PEACHI project develops vaccine strategies targeting both HIV and hepatitis C virus

An estimated 2.3 million people globally are infected with both human immunodeficiency virus type 1 and hepatitis C virus.

27 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

Study findings could open new possibilities for treating cancer with adenovirus

Adenovirus is a common virus that causes infectious diseases of the respiratory tract, eyes and gastrointestinal tract in humans and animals. Researchers at Umeå University study molecular mechanisms of infection in order to understand how adenovirus causes disease.

20 Apr 2018

BD introduces new informatics and automation solutions for clinical laboratories

BD (Becton, Dickinson and Company), a leading global medical technology company, today introduced several new informatics and automation solutions for clinical laboratories, which may play a critical role in the fight against infectious diseases and antimicrobial resistance.

From BD (Becton, Dickinson and Company) 20 Apr 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Researchers reveal promising method for delivering cancer virotherapy

Researchers at Okayama University report in Scientific Reports a promising method for delivering viral DNA, able to eliminate cancerous cells, to a tumor. The approach, involving encapsulation of the DNA in liposomes, has the potential to enable intravenous delivery of virus-based antitumor agents.

6 Feb 2018

Stealth gene shuttles open up new avenues to treat aggressive cancers

Viruses have their own genetic material and can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell.

31 Jan 2018

UCLA expert suggests measures for reducing risk of getting sick during holiday travel

It's that time of year when families jet off to all parts of the country – and the globe - to share some holiday cheer. Unfortunately, all that travel forces people into often-crowded airplanes, automobiles and airports. And there's the sharing of hugs and kisses with loved ones upon arrival at their destination.

28 Dec 2017