Autoantibodies News and Research

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Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

The National Institutes of Health has awarded Virginia Commonwealth University a grant totaling $1.8 million to study the biology of allergic disease - work which may one day point researchers to the development of therapies to fight asthma, allergy and inflammatory conditions such as rheumatoid arthritis, multiple sclerosis and heart disease.

18 Jul 2013

Researchers identify risk factor for maternal antibody-related autism in subset of children

Researchers with the UC Davis MIND Institute have found that prenatal exposure to specific combinations of antibodies found only in mothers of children with autism leads to changes in the brain that adversely affect behavior and development.

10 Jul 2013

Tiny RNA molecules work as powerful regulators of immune response in mammals

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.

1 Jul 2013

Study: Multiple islet autoantibodies in children indicate risk of developing type 1 diabetes

A decade-long JDRF-funded study led by the Institute of Diabetes Research in Helmholtz Zentrum M-nchen, Germany, is providing a deeper understanding of the link between autoantibodies and the risk of developing type 1 diabetes, highlighting the importance of pre-diabetes research into possible preventions for the disease.

20 Jun 2013

Mayo researchers find rheumatic condition gout may be due to flare-ups in other joints

The painful rheumatic condition gout is often associated with the big toe, but it turns out that patients at highest risk of further flare-ups are those whose gout first involved other joints, such as a knee or elbow, Mayo Clinic has found.

15 Jun 2013

Winners of EFIC-Grünenthal-Grant announced

For the 8th time the European Federation of IASP Chapters in cooperation with the pharmaceutical company Grünenthal Group announced the EFIC-Grünenthal-Grant (E-G-G) - a grant aimed to support young scientists at an early stage of their experimental projects on clinical and human volunteer-based pain research.

6 Jun 2013

Lupus Foundation of America announces Career Development Award and new summer fellowships

The Lupus Foundation of America, the only national force dedicated to solving the cruel mystery of lupus, announced recipients of five new summer fellowships and the Foundation's first-ever Career Development Award.

3 Jun 2013

Johns Hopkins researchers find possible trigger of rheumatoid arthritis

In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a disease-promoting role.

23 May 2013

EventusDx receives CE mark designation for Octava Pink breast cancer test

Eventus Diagnostics, Inc. today announced that it has received CE mark designation for its Octava Pink™ breast cancer test intended for confirmatory use in women who have received negative mammography results.

2 May 2013

Study shows human blood contains 1000’s of autoantibodies to clear cellular debris caused by injury, disease

In a study that suggests a new frontier in immunology, scientists at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine (UMDNJ-SOM) report on evidence that shows human blood contains thousands of autoantibodies that bind specifically to antigens from organs and tissues all over the body and act to clear cellular debris that results from injury and disease.

10 Apr 2013

Study applying OPKO Health's technology to identify synthetic peptoid in NMO patient serum published

OPKO Health, Inc. today announced the publication of a study applying its novel library screening technology to identify a synthetic peptoid that binds to anti-Aquaporin 4 antibodies in the serum of patients with Neuromyelitis optica.

6 Apr 2013

Scientists identify specific cellular events that appear key to lupus

A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent weapon against the disease.

5 Feb 2013

New insights into relationship between autoimmunity and brain function

A study published in the current issue of Psychotherapy and Psychosomatics by a group of French investigators of the University of Paris unravels new insights as to the relationship between autoimmunity and brain function.

30 Nov 2012

Overweight, smoking add to rheumatoid arthritis risk

Lifestyle changes could reduce the risk for rheumatoid arthritis in patients predisposed to the condition, Dutch researchers suggest.

5 Nov 2012

Autoantibody aids identification of hyperexcitability disorders

Researchers have found that testing for a glycine receptor autoantibody aids the identification of a broad spectrum of autoimmune brainstem/spinal cord hyperexcitability disorders.

29 Oct 2012

Autoimmune disease myasthenia gravis halted in mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

1 Oct 2012

Lund University professor to coordinate oral insulin study for type 1 diabetes

Type 1 diabetes is the autoimmune form of diabetes, in which the patients' insulin-producing beta cells are destroyed by their own immune system. "We know that if a person has two autoantibodies and one of them is against insulin, there is a 50 per cent risk that they will develop type 1 diabetes within five years. It doesn't matter how old you are", says Ake Lernmark, Professor of Experimental Diabetes Research at Lund University in Sweden.

20 Sep 2012

Simple assay to improve treatment for idiopathic membranous nephropathy

Simple blood tests could help physicians decide which patients with a particular autoimmune kidney disease can forgo potentially toxic medications and which need to be treated, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

7 Sep 2012

Therapeutic targets for pemphigus vulgaris discovered

Researchers have identified the primary target of the autoantibodies found in the serum of patients with the blistering skin disorder pemphigus vulgaris.

7 Sep 2012

Potassium-channel autoimmunity linked to chronic pain

A substantial proportion of patients with voltage-gated potassium channel-complex autoimmunity experience chronic idiopathic pain, although the specific antigenic complex associated with pain remains to be determined, conclude US scientists.

3 Sep 2012