Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Soyasapogenol B: A new drug delivery technology for therapeutics

Multi-Walled Carbon Nanotubes (MWCNTs) are characterized by walls formed by a one atom thick sheet of carbon.

24 Dec 2018

Study: Cholesterol uptake is decreased in GM3S-deficient cells

Approximately 1 in every 4 deaths in the United States is caused by heart disease, according to the Centers for Disease Control and Prevention.

21 Dec 2018

Breast tumors recruit bone marrow cells to boost their growth, study reveals

Tel Aviv University researchers have discovered that breast cancer tumors boost their growth by recruiting stromal cells that originate in bone marrow.

10 Dec 2018

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Proteins are polymers of amino acids that are linked by peptide bonds and they are one of the major classes of bio-molecules existing in a living organism. Proteins are involved in various cellular functions and events like cell signaling, cell adhesion, metabolic reactions, in the generation of immune response and many more.

10 Dec 2018

Newly developed molecules may provide more reliable relief for people with autoimmune diseases

Living with an autoimmune disease can feel like an insider is attacking your body. An estimated 24 million people in the United States are affected by autoimmune diseases, a group of diseases in which a person's immune system attacks part of the person's own body.

7 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

Scientists alleviate schizophrenic symptoms in mice

Despite extensive research efforts, schizophrenia remains one of the least understood brain disorders. One promising area of research is in receptors on the surfaces of brain cells that help sense growth factors.

30 Nov 2018

New ointment for treating brown recluse spider bites is tested on humans

The bite from a brown recluse spider (Loxosceles) can cause skin necrosis, renal failure, and even death. A new ointment is being tested in Brazil, however. Its effects have already been proven in tests conducted in cell cultures and animal models.

29 Nov 2018

Rainforest vine compound makes pancreatic cancer cells susceptible to nutrient starvation

Pancreatic cancer cells are known for their ability to thrive under extreme conditions of low nutrients and oxygen, a trait known in the cancer field as "austerity." The cells' remarkable resistance to starvation is one reason why pancreatic cancer is so deadly.

14 Nov 2018

Research explores how exercise may help fight drug addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder.

14 Nov 2018

Case Western Reserve School of Medicine receives NIH grant for undergraduate cancer research

Case Western Reserve University School of Medicine is preparing and inspiring a new generation of cancer investigators through Cancer-focused Summer Undergraduate Research.

7 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

Individual heart cells respond differently to high blood pressure

A team of cardiologists have found that single cells within the heart are affected by high blood pressure in different ways. Some adapt, whilst others fail.

30 Oct 2018

Molecular breakthrough may improve prognosis for pancreatic cancer

Scientists have discovered a method by which fibroblasts in the stroma of pancreatic tumors can be reprogrammed to suppress tumor cell growth.

26 Oct 2018

New $3.3 million grant will fund human cell atlas of type 1 diabetes

The mechanism leading to development of type 1 diabetes remains a mystery, hampering the ability to find new ways to prevent, treat or even cure this condition.

25 Oct 2018

Researchers examine SSRI use during pregnancy and major gestational malformations

A comprehensive new review article presents the most current understanding of the role selective serotonin reuptake inhibitors play in increased risk of multiple diverse gestational malformations and takes aim at the ongoing debate over whether SSRIs as a drug class can cause these malformations.

16 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

Using pulsed electric fields in cancer therapy

Pulsed electric fields are helping fight cancer, whether by inducing tumor cell death or by stimulating the immune system.

11 Oct 2018

Researchers aim to create more authentic organoids for drug testing, transplantation

Human embryos start as a tiny mass of cells that are all the same. The first step in growing from a homogenous ball of cells into a complex individual with distinct organs and tissues is for the cells to divide into distinct populations.

10 Oct 2018