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$The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series$

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Researchers evaluated the vaccine effectiveness of half-doses of AZD1222 or BNT162b2 COVID-19 vaccines as a booster dose following primary series vaccination with CoronaVac.

6 Oct 2022

PerkinElmer’s Oxford Immunotec receives U.S. FDA approval for T-cell select to automate clinically superior tuberculosis detection

PerkinElmer’s (NYSE: PKI) Oxford Immunotec today announced the U.S. Food and Drug Administration (FDA) has approved the use of the T-Cell Select™ reagent kit for the automation of its T-SPOT®.TB test workflow for in vitro diagnostic (IVD) use by certified laboratories.

From Oxford Immunotec 6 Oct 2022

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Researchers determined the T cell response to the NVX-CoV2373, an adjuvanted recombinant full-length SARS-CoV-2 spike (S) trimer protein vaccine.

5 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

In a new study, researchers designed a liquid biomarker panel consisting of macrophage and monocyte-related soluble factors and circulating spike proteins to understand profiles of immune dysregulation in patients with post-acute sequelae of COVID-19.

22 Sep 2022

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

New device for diagnosing bone fragility approved for marketing in the Europe

A new device for diagnosing bone fragility invented by the University Hospitals of Geneva and the University of Geneva has been approved for marketing in the European Economic Area and Switzerland.

20 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

University of Arkansas receives NIST award to improve palm-sized, low-cost and wireless COVID sensor

The National Institute of Standards and Technology, via an application from the RAPID Manufacturing Institute, awarded the University of Arkansas $699,604 to improve a Wi-Fi nano-biosensor that will be used in a palm-sized, low-cost and wireless SARS-COV-II detection system.

16 Sep 2022

ValitaCell joins Beckman Coulter Life Sciences

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces it has acquired ValitaCell Ltd., a biotechnology company that creates pioneering analytical products and technologies for the biopharmaceutical industry.

From Beckman Coulter Life Sciences 16 Sep 2022

Excessive smartphone use may lead to early puberty

Exposure to blue light via regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented today at the 60th Annual European Society for Paediatric Endocrinology Meeting.

16 Sep 2022

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

In a new study, researchers explored the antiviral activity of the bovine seminal plasma protein PDC-109 against various mammalian viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

Simple phone-based outreach strategy can help engage low-income smokers to try quitting tobacco

New findings published in Nicotine & Tobacco Research show a simple, but valuable approach can help engage low-income smokers to try quitting tobacco.

14 Sep 2022

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

In a new study, researchers assessed the immunogenicity, safety, and booster-efficacy of the Modified Vaccinia virus Ankara-Bavarian Nordic (MVA-BN) vaccine currently being used for immunization against monkeypox.