Hypothalamus News and Research

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The Hypothalamus is the area of the brain that controls body temperature, hunger, and thirst.

Study examines risks and benefits of testosterone therapy for older men

According to a statement issued today by the Endocrine Society, the risks and benefits of testosterone therapy for older men with declining levels of the hormone need to be fully evaluated.

10 Feb 2014

New study provides important understanding of what drives appetite

While the function of eating is to nourish the body, this is not what actually compels us to seek out food. Instead, it is hunger, with its stomach-growling sensations and gnawing pangs that propels us to the refrigerator - or the deli or the vending machine. Although hunger is essential for survival, abnormal hunger can lead to obesity and eating disorders, widespread problems now reaching near-epidemic proportions around the world.

9 Feb 2014

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

According to the National Institute of Mental Health, over 18 percent of American adults suffer from anxiety disorders, characterized as excessive worry or tension that often leads to other physical symptoms. Previous studies of anxiety in the brain have focused on the amygdala, an area known to play a role in fear.

31 Jan 2014

TherapeuticsMD starts TX 12-002-HR phase 3 clinical trial for secondary amenorrhea

TherapeuticsMD, Inc., a women's healthcare company, announced today that it has initiated the SPRY Trial, a randomized, placebo-controlled phase 3 clinical trial designed to evaluate the safety and efficacy of TX 12-002-HR, its oral progesterone candidate for secondary amenorrhea, a condition treated to maintain fertility in young premenopausal women.

24 Jan 2014

BRAF mutation associated with other cancers appears to drive papillary craniopharyngiomas

A team led by investigators from Massachusetts General Hospital, Brigham and Women's Hospital and the Broad Institute has found that a gene mutation associated with several types of cancer also may be responsible for a rare but debilitating brain tumor called papillary craniopharyngioma.

13 Jan 2014

Study sheds light on the biological underpinnings of obesity

A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the treatment of obesity and may help explain why medications that are prescribed for epilepsy and other conditions that interfere with this protein, such as gabapentin and pregabalin, can cause weight gain.

7 Jan 2014

New research shows that the brain can produce and release estrogen

A University of Wisconsin-Madison research team reports today that the brain can produce and release estrogen - a discovery that may lead to a better understanding of hormonal changes observed from before birth throughout the entire aging process.

5 Dec 2013

Pregnant women may transmit effects of stress to child by way of bacteria in vagina and placenta

Pregnant women may transmit the damaging effects of stress to their unborn child by way of the bacteria in their vagina and through the placenta, suggest new findings from two animal studies presented by researchers at the University of Pennsylvania at Neuroscience 2013, the annual meeting of the Society for Neuroscience.

12 Nov 2013

Study shows that different brain regions process different types of fear

What do bullies and sex have in common? Based on work by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, it seems that the same part of the brain reacts to both.

11 Nov 2013

Diets and the famine reaction: an interview with Associate Professor Amanda Salis, University of Sydney

The statistic that you often hear is that 95% of diets fail, but in actual fact, emerging research is now showing that it’s around 70% of diets that fail. That means that around 30% of people who are losing weight are actually keeping it off. So we’re doing better now than we were doing in the past, but there’s still work to be done.

7 Nov 2013

Normal blood sugar regulation depends on partnership between pancreas and brain

A growing body of evidence suggests that the brain plays a key role in glucose regulation and the development of type 2 diabetes, researchers write in the Nov. 7 issue of the journal Nature.

6 Nov 2013

Researchers highlight presence of specific antibodies that regulate appetite in obese patients

Obesity affects more than 15% of adults in France, and its constitutive mechanisms are still not completely explained. Normally, fine control of weight and food intake is coordinated by a specialised part of the brain (the hypothalamus).

31 Oct 2013

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Interestingly, a recent study found that ischemic stress causes hyperglycemia and may worsen ischemic neuronal damage. In addition, decreased insulin sensitivity after ischemic stress seems to be involved in the development of post-ischemic glucose intolerance.

30 Oct 2013

Researchers identify link between neuronal activity in lateral hypothalamus and state of REM sleep

A team of scientists led by Dr. Antoine Adamantidis, a researcher at the Douglas Mental Health University Institute and an assistant professor at McGill University, has released the findings from their latest study, which will appear in the October issue of the prestigious scientific journal Nature Neuroscience.

3 Oct 2013

New insights into how obesity, type 2 diabetes can create stress response in the brain

Joslin researchers have gained new insights into how obesity and type 2 diabetes can create a stress response in the brain, especially in the hypothalamus (the brain region that regulates appetite and energy production), that may contribute to altering metabolism throughout the body. The findings are reported in the October issue of the Journal of Clinical Investigation.

2 Oct 2013

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Sixty years ago scientists could electrically stimulate a region of a mouse's brain causing the mouse to eat, whether hungry or not. Now researchers from UNC School of Medicine have pinpointed the precise cellular connections responsible for triggering that behavior.

27 Sep 2013

Research offers focused explanation for cardiac arrest predilection for morning hours

Evidence from people with heart disease strongly supports the existence of the molecular link first discovered in laboratory mice between the body's natural circadian rhythms and cardiac arrest or sudden cardiac death (SCD) - the No. 1 cause of death in heart attacks, a scientist said here today.

10 Sep 2013

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

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4 Sep 2013

New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

Researchers identify mechanisms necessary to live without insulin

Several millions of people around the world suffer from insulin deficiencies. Insulin is a hormone, secreted by the beta cells in the pancreas, which plays a major role in the regulation of energy substrates such as glucose.

4 Sep 2013

Hypothalamus News and Research

Further Reading

Study examines risks and benefits of testosterone therapy for older men

New study provides important understanding of what drives appetite

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

TherapeuticsMD starts TX 12-002-HR phase 3 clinical trial for secondary amenorrhea

BRAF mutation associated with other cancers appears to drive papillary craniopharyngiomas

Study sheds light on the biological underpinnings of obesity

New research shows that the brain can produce and release estrogen

Pregnant women may transmit effects of stress to child by way of bacteria in vagina and placenta

Study shows that different brain regions process different types of fear

Diets and the famine reaction: an interview with Associate Professor Amanda Salis, University of Sydney

Normal blood sugar regulation depends on partnership between pancreas and brain

Researchers highlight presence of specific antibodies that regulate appetite in obese patients

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Researchers identify link between neuronal activity in lateral hypothalamus and state of REM sleep

New insights into how obesity, type 2 diabetes can create stress response in the brain

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Research offers focused explanation for cardiac arrest predilection for morning hours

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

New mechanism operates specific protein in brain to bring delay in aging

Researchers identify mechanisms necessary to live without insulin

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