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Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Researchers assessed the characteristics of the brain fog reported by some COVID-19 patients.

17 Jun 2022

Scientists characterize type I IFN response during SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, Canadian researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on interferon (IFN) response.

15 Jun 2022

New test can tell if you are immune to SARS-CoV-2

In a recent study published in the journal Nature Biotechnology, an international team of researchers developed and evaluated quantitative polymerase chain reaction (qPCR)-based assays to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific functional T cell immunity.

15 Jun 2022

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

Researchers assessed the interactions between SARS-CoV-2 and ACE2.

14 Jun 2022

Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

Researchers assessed the variation in SARS-CoV-2 manifestation with age.

13 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Study sheds new light on the role of transcription factors in bone marrow microenvironments

In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them.

9 Jun 2022

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Researchers assessed the interactions between carbon nanotubes and SARS-CoV-2.

7 Jun 2022

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Researchers at the University of Michigan Rogel Cancer Center have found a cell nuclear receptor activated by high fat diets and synthetic substances in unregulated athletic performance enhancers fuels the progression of precancerous pancreas lesions into pancreatic cancer.

1 Jun 2022

Ligand News and Research

Lipid-peptide nanocomplexes offer new mRNA platform

SARS-CoV-2 evades natural killer cell cytotoxic responses

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Scientists characterize type I IFN response during SARS-CoV-2 infection

New test can tell if you are immune to SARS-CoV-2

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

A comparison of SARS-CoV-2 and influenza cytokine storms

Study sheds new light on the role of transcription factors in bone marrow microenvironments

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Tracking the emergence of potential drug-resistant mutations in SARS-CoV-2 proteins

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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