Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

New approach holds great promise for developing effective treatments for human mitochondrial diseases

Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.

21 Jul 2015

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA.

15 Jul 2015

$Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients$

Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

End-stage renal disease (ERSD) is the last stage of chronic kidney disease where the kidneys function at under 10 to 15 percent of their normal capacity. At this stage, kidneys cannot effectively remove waste or excess fluid from the blood system, and dialysis or a kidney transplant is necessary to live.

14 Jul 2015

University of Leeds scientists uncover genes implicated in common inherited diseases

Scientists from the University of Leeds have uncovered the most comprehensive list yet of genes implicated in a group of common inherited diseases.

14 Jul 2015

Blood-borne molecule promotes age-related cognitive decline

A blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline, suggests a new study by researchers at UC San Francisco and Stanford School of Medicine.

7 Jul 2015

DaVita Kidney Care offers recipes to help CKD patients maintain healthy diet during Fourth of July weekend

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, offers recipes that can help people with chronic kidney disease (CKD) maintain a healthy diet during the Fourth of July weekend.

2 Jul 2015

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Inhibikase Therapeutics, Inc. announces the receipt of a Phase II SBIR grant in the amount of $1.54 million dollars from the U.S. National Institutes of Health to advance its novel Re-engineering with Metabolism Preserved (RAMP) medicinal chemistry program.

29 Jun 2015

DaVita Kidney Care recognizes June as National Men's Health Month

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, recognizes the month of June as National Men's Health Month and the importance of bringing awareness to the health care issues that affect men.

26 Jun 2015

New strategies may help clinicians and hospitals better manage patients with chronic conditions

Experts have identified strategies for using electronic health records to improve care for patients with chronic kidney disease. The guidance, which will appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies.

26 Jun 2015

Experts identify new strategies for using EHRs to treat chronic kidney disease patients

Experts have identified new strategies for using electronic health records (EHRs) to treat patients with chronic kidney disease. These recommendations may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies.

26 Jun 2015

UC Santa Barbara professor develops novel therapeutic strategy for PKD

For the 12 million people worldwide who suffer from polycystic kidney disease (PKD), an inherited disorder with no known cure, a new treatment option may be on the horizon.

26 Jun 2015

Study reveals how geography affects the survival of people with end-stage kidney disease

The notion that geography often shapes economic and political destiny has long informed the work of economists and political scholars. Now a study led by medical scientists at Johns Hopkins reveals how geography also appears to affect the very survival of people with end-stage kidney disease in need of dialysis.

24 Jun 2015

First ESC recommendations for patients with cardiac arrhythmias, CKD published in EP Europace

The first ESC recommendations for patients with cardiac arrhythmias and chronic kidney disease (CKD) are presented today at EHRA EUROPACE - CARDIOSTIM 2015 and published in EP Europace.

24 Jun 2015

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

AstraZeneca today announced a three-year research collaboration with the French National Institute of Health and Medical Research (Inserm) to investigate new therapeutic approaches totype 2 diabetes and Chronic Kidney Disease.

18 Jun 2015

University of Michigan, AstraZeneca team up to identify novel targets for chronic kidney disease

AstraZeneca today announced a two-year research collaboration with the University of Michigan to advance the treatment of chronic kidney disease (CKD) through the improved understanding of the disease. The collaboration will tackle the challenging area of identifying novel targets for the treatment of CKD, focusing on the use ofpatient tissue and validation of preclinical models.

18 Jun 2015

Link between poverty and kidney disease changes over time, shows study

Poverty is known to be a strong risk factor for end-stage kidney disease. Now, a first of-its-kind study has found that the association between poverty and kidney disease changes over time.

17 Jun 2015

Link between poverty and kidney disease changes over time, study finds

Poverty is known to be a strong risk factor for end-stage kidney disease. Now, a first of-its-kind study has found that the association between poverty and kidney disease changes over time.

16 Jun 2015

New technique slows progression of polycystic kidney disease in mice

A new technique for treating polycystic kidney disease has been identified by researchers based at the UCL Institute of Child Health. Published in the Journal of the American Society of Nephrology, the treatment, which involves targeting tiny blood and lymphatic vessels inside the kidneys, is shown to improve renal function and slow progression of disease in mice.

8 Jun 2015

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

Withholding angiotensin receptor blockers (ARBs) for longer than two days after surgery is associated with a significantly increased risk of postoperative death, according to a study of more than 30,000 patients in the VA health care system by researchers at UC San Francisco and the San Francisco VA Medical Center.

5 Jun 2015

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that dosing has begun in a first-in-human Phase I clinical study of RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of microRNA-21 ("miR-21").

4 Jun 2015

Nephropathy News and Research

Further Reading

New approach holds great promise for developing effective treatments for human mitochondrial diseases

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

University of Leeds scientists uncover genes implicated in common inherited diseases

Blood-borne molecule promotes age-related cognitive decline

DaVita Kidney Care offers recipes to help CKD patients maintain healthy diet during Fourth of July weekend

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

DaVita Kidney Care recognizes June as National Men's Health Month

New strategies may help clinicians and hospitals better manage patients with chronic conditions

Experts identify new strategies for using EHRs to treat chronic kidney disease patients

UC Santa Barbara professor develops novel therapeutic strategy for PKD

Study reveals how geography affects the survival of people with end-stage kidney disease

First ESC recommendations for patients with cardiac arrhythmias, CKD published in EP Europace

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

University of Michigan, AstraZeneca team up to identify novel targets for chronic kidney disease

Link between poverty and kidney disease changes over time, shows study

Link between poverty and kidney disease changes over time, study finds

New technique slows progression of polycystic kidney disease in mice

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

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