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Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Blood cancer sufferers could be treated with a simple arthritis drug, scientists at the University of Sheffield have discovered.

3 Aug 2017

NIH researchers show how investigational drug works against rare, fatal genetic disease

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).

17 Jul 2017

UCLA-led study reveals possibility of CMV and HIV transmission from mothers to infants

HIV-positive women with cytomegalovirus, or CMV, in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV, the virus that causes AIDS, to their infants, according to a UCLA-led study.

22 Jun 2017

Penn study reveals new molecular pilot light required to turn on brown fat furnace

As we bask in the summer heat, it is easy to take for granted that humans are also prepared for the cold of winter, with overcoats in the closet and home heating systems ready to be fired up as an added assurance against falling temperatures.

15 Jun 2017

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Researchers in the University of Maryland Fischell Department of Bioengineering (BIOE) Jewell Laboratory are using quantum dots - tiny semiconductor particles commonly used in nanotechnology - to decipher the features needed to design specific and effective therapies for multiple sclerosis (MS) and other autoimmune diseases.

14 Jun 2017

Researchers uncover novel and non-invasive way to track dengue infection

Commonly used to detect solid tumors, positron emission tomography (PET) paired with the glucose metabolism probe, fluorodeoxyglucose (FDG), is considered 'old' technology in the field of cancer.

6 Jun 2017

LMU researchers show how genetic variant in people of African ancestry modulates immune cells

A genetic variant that is particularly prevalent in people of African ancestry confers protection against malaria. LMU researchers have now shown how it modulates the properties of white blood cells that play a major role in immune defenses and inflammation.

1 Jun 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Researchers discover novel mechanism that causes malignant pleural effusion in lung cancer patients

Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall. Researchers at the Helmholtz Zentrum München, in partnership with the German Center for Lung Research, have discovered a novel mechanism that causes this to happen.

19 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

UAB symposium highlights use of tissue engineering to repair broken hearts

The third annual Cardiovascular Tissue Engineering Symposium met at the University of Alabama at Birmingham last month, a gathering of noted physicians and scientists who share the goal of creating new tissues and new knowledge that can prevent or repair heart disease and heart attacks.

9 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a team of researchers at the Medical University of South Carolina and the Dartmouth-Hitchcock Norris Cotton Cancer Center In the April 14, 2017, Science Immunology.

28 Apr 2017

Dietary soy-protein may be effective adjunct therapy for inflammatory bowel diseases

A diet supplemented with soy protein may be an effective adjunct therapy for inflammatory bowel diseases, Penn State researchers reported after completing a study that included mice and cultured human colon cells.

26 Apr 2017

Parents can pass damaging effects of nighttime light exposure to offspring, study finds

Animals can pass the damaging effects of nighttime light exposure to their offspring, a new study has found, adding to a growing body of evidence that there's a health cost to our increasingly illuminated nights.

31 Mar 2017

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

Early treatment with stem cells can safely help recovery in stroke patients, study shows

A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.

20 Mar 2017

New method can precisely track replication of yellow fever virus in host immune cells

Researchers from Princeton University's Department of Molecular Biology have developed a new method that can precisely track the replication of yellow fever virus in individual host immune cells.

14 Mar 2017