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Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

Researchers used drug-target Mendelian randomization to test whether genetically proxied activation of GLP1R and GIPR influences alcohol-related behaviors. They found that GIPR, especially when combined with GLP1R, was linked to lower binge and heavy drinking, healthier food preferences, improved liver markers, and reduced coronary artery disease risk.

15 Sep 2025

Electrical stimulation predicts recovery potential after acute nerve injuries

This study found that, in rats, acute nerve injuries that may recover can be distinguished from those that are unlikely to recover based on the response to intraoperative electrical nerve stimulation in the acute clinical setting.

13 Sep 2025

AI-powered hydrogel dressings transform chronic wound care

As chronic wounds such as diabetic ulcers, pressure ulcers, and articular wounds continue to challenge global healthcare systems, a team of researchers from China has introduced a promising innovation: AI-integrated conductive hydrogel dressings for intelligent wound monitoring and healing.

12 Sep 2025

Green tea extract reduces weight and improves glucose control in obese mice

Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes.

10 Sep 2025

Precision nutrition offers new pathways to slow biological aging

Diet doesn't just fuel the body, it sends molecular signals that can slow down or speed up biological aging, according to a new perspective in npj Aging (Nature Portfolio).

10 Sep 2025

Can gaming strengthen the brain’s attention pathways?

Research reveals structural brain differences in action gamers, with greater cortical thickness and connectivity in regions vital for visuospatial processing.

8 Sep 2025

Innovative approach advances equity in health care AI

A team of researchers at the Icahn School of Medicine at Mount Sinai has developed a new method to identify and reduce biases in datasets used to train machine-learning algorithms-addressing a critical issue that can affect diagnostic accuracy and treatment decisions.

5 Sep 2025

Targeting ADAR1 offers new hope against glioblastoma

The most common and aggressive type of adult brain cancer, glioblastoma multiforme (GBM) is notoriously resistant to treatment, with a median survival of just 14 months following diagnosis.

5 Sep 2025

New clinical trial to test sensory-enabled neural prostheses for upper limb amputees

Technology developed at Case Western Reserve University can restore a sense of touch that makes a prosthetic hand feel like a part of one's own body instead of feeling artificial and disconnected.

5 Sep 2025

Mucus-inspired hydrogel improves healing in animal models of gastric injury

Hydrogels-materials like gelatin that can absorb and hold water-can aid wound healing and enable slow-release drug delivery, but they usually break down in acidic environments like the stomach.

4 Sep 2025

Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses.

4 Sep 2025

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

CN Bio adds computational modeling capabilities to ADME services for enhanced bioavailability profiling

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the expansion of its Contract Research Services (CRS) with new PhysioMimix® computational modeling tools.

3 Sep 2025

Platelets found to mop up DNA fragments and improve early cancer detection

Platelets are probably best known for their role in blood clotting, making scabs and related, if less salubrious, contributions to heart attacks and strokes.

2 Sep 2025

Study reveals how dormant E. coli bacteria survive antibiotics

A groundbreaking study by researchers from Wuhan University, York University (UK), and Peking University has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions.

2 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025