Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

First Edition: June 12, 2014

Today's headlines include stories examining how Eric Cantor's primary defeat will change the House GOP leadership and the Republican strategy to replace the health law.

12 Jun 2014

Low cholesterol may increase mortality risk in patients with kidney cancer

People are often told to reduce their cholesterol to improve their heart health, but new research suggests that low cholesterol may increase kidney cancer patients' risk of dying from their disease. The findings, which are published in BJU International, indicate that cholesterol testing may help doctors as they monitor and treat patients with kidney cancer.

12 Jun 2014

Study supports proposal to screen all men with gout for presence of ED

A new study presented today at the European League Against Rheumatism Annual Congress showed that erectile dysfunction (ED) is present in most men with gout and is frequently severe.

12 Jun 2014

High-protein diets lower stroke risk

People with diets higher in protein, especially from fish, may be less likely to have a stroke than those with diets lower in protein, according to a meta-analysis published in the June 11, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2014

Intake of monounsaturated fatty acids, cholesterol influence disease activity in RA and OA respectively

Two new studies presented today at the European League Against Rheumatism Annual Congress have helped clarify the relationship between the dietary intake of monounsaturated fatty acids and cholesterol with disease activity in rheumatoid arthritis (RA) and osteoarthritis (OA) respectively.

12 Jun 2014

Bacteria must be considered part of overall pathology of atherosclerosis

Scientists believe they have an explanation for the axiom that stress, emotional shock, or overexertion may trigger heart attacks in vulnerable people. Hormones released during these events appear to cause bacterial biofilms on arterial walls to disperse, allowing plaque deposits to rupture into the bloodstream, according to research published in published today in mBio-, the online open-access journal of the American Society for Microbiology.

11 Jun 2014

New prescription weight-loss medication combines antidepressant with addiction medication

A new prescription weight-loss medication that combines a popular antidepressant with a medication for addiction will be reviewed by the Federal Drug Administration (FDA) for potential approval.

11 Jun 2014

Researchers examine effects of testosterone on women after menopause

Testosterone supplementation for women is a hot topic. A new pharmacokinetics study of a brand of testosterone cream for women approved in Western Australia has been published online in Menopause, the journal of The North American Menopause Society (NAMS).

11 Jun 2014

FDA grants orphan drug designation to EffRx Pharmaceuticals' EX404 for treatment of PCOS

EffRx Pharmaceuticals SA, a specialty pharmaceutical company, today announced that the U.S. Food and Drug Administration has granted orphan drug designation to its proprietary metformin-based product candidate, EX404, for the treatment of pediatric polycystic ovary syndrome (PCOS).

11 Jun 2014

Advances in understanding of genetics of CAD lead to more therapeutic targets

Advances in the understanding of the genetics of coronary artery disease, or CAD, will revitalize the field and lead to more therapeutic targets for new medicines to combat this common disease, suggests a genetics expert from the Perelman School of Medicine at the University of Pennsylvania in a Perspective article in the new issue of Science Translational Medicine.

9 Jun 2014

Studies confirm importance of men seeing physician on regular basis

For many men being a father is about staying strong as they protect and care for their family. Some men see going to the doctor as a weakness or nuisance, but protecting your health is one of the best things a father can do for his family.

6 Jun 2014

Researchers emphasize critical need to utilize multi-pronged approach to treat diabetes mellitus

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University; Marc A. Pfeffer, M.D., Dzau professor of medicine at Harvard Medical School; John W. Newcomer, M.D., executive vice dean of FAU's College of Medicine and interim vice president for research at FAU; Paul S. Jellinger, M.D., affiliate professor at the University of Miami Miller School of Medicine; and Alan Garber, M.D., Ph.D., professor of medicine at Baylor, have published a commentary in the American Journal of Managed Care titled "Treatment of Diabetes Mellitus: The Urgent Need for Multifactorial Interventions."

4 Jun 2014

Researchers find way to prevent nonalcoholic fatty liver disease

Studying mice, researchers have found a way to prevent nonalcoholic fatty liver disease, the most common cause of chronic liver disease worldwide.

4 Jun 2014

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease.

3 Jun 2014

New discovery may shed light on how common cold triggers asthma attacks

Cold season may be just behind us, but a new discovery may shed light on how this common condition triggers asthma attacks. In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold.

3 Jun 2014

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

Cerenis Therapeutics, the biopharmaceutical company, today announced that two of its Phase II studies, SAMBA and MODE (Modifying Orphan Disease Evaluation), with CER-001, an engineered human apoA-I-containing pre-β HDL mimetic, met their primary clinical endpoints in patients with Familial Primary Hypoalphalipoproteinemia (FPHA) and Homozygous Familial Hypercholesterolemia (HoFH), respectively.

2 Jun 2014

Discontinuing statins in patients with advanced illnesses improves quality of life

People in the late stages of cancer and other terminal illnesses are not only unharmed by discontinuing statins for cholesterol management, they may benefit, according to a study presented Friday by researchers at Duke Medicine representing a national research network.

31 May 2014

Signs and symptoms of diabetes

You're approaching 50 and can't help but notice the signs of aging - your vision and hearing aren't what they used to be, and it seems your cuts and bruises take longer to heal.

30 May 2014

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile - based on a simple blood test - may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

30 May 2014

People with high levels of cynical distrust more likely to develop dementia, says study

People with high levels of cynical distrust may be more likely to develop dementia, according to a study published in the May 28, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

29 May 2014

Cholesterol News and Research

Further Reading

First Edition: June 12, 2014

Low cholesterol may increase mortality risk in patients with kidney cancer

Study supports proposal to screen all men with gout for presence of ED

High-protein diets lower stroke risk

Intake of monounsaturated fatty acids, cholesterol influence disease activity in RA and OA respectively

Bacteria must be considered part of overall pathology of atherosclerosis

New prescription weight-loss medication combines antidepressant with addiction medication

Researchers examine effects of testosterone on women after menopause

FDA grants orphan drug designation to EffRx Pharmaceuticals' EX404 for treatment of PCOS

Advances in understanding of genetics of CAD lead to more therapeutic targets

Studies confirm importance of men seeing physician on regular basis

Researchers emphasize critical need to utilize multi-pronged approach to treat diabetes mellitus

Researchers find way to prevent nonalcoholic fatty liver disease

NYU Langone scientists identify promising treatment target for Alzheimer's disease

New discovery may shed light on how common cold triggers asthma attacks

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

Discontinuing statins in patients with advanced illnesses improves quality of life

Signs and symptoms of diabetes

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

People with high levels of cynical distrust more likely to develop dementia, says study

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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