immunity News and Research

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Response to a third SARS-CoV-2 vaccine dose amongst immunocompromised

In a research paper recently uploaded to the preprint server medRxiv* by Schrezenmeier et al. (August 12th, 2021) the potential benefit of three vaccine doses in either a homogenous or heterogeneous dosing regimen amongst kidney transplant patients is assessed, finding that the search for viable vaccination approaches amongst these patients remains an urgent medical need.

16 Aug 2021

Researchers assess the genetic features of T-cell immunity development to SARS-CoV-2 variants

The continuing emergence of new SARS-CoV-2 mutations allows the virus to spread more effectively and evade antibodies. However, it is unclear whether new strains are capable of evading T-cell immunity - one of the body's main lines of defense against COVID-19.

16 Aug 2021

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

In a recent bioRxiv* preprint research paper, a large group of US scientists demonstrate how a booster dose of the mRNA-1273 vaccine can substantially improve both the potency and range of neutralizing antibody responses and mediate protection against upper and lower airway infection by a range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern – even those relatively resistant to in vitro neutralization.

16 Aug 2021

First dose of COVID-19 vaccine to be offered to all young people aged 16 to 17 in England

All young people aged 16 to 17 in England are to be offered the first dose of a COVID-19 vaccine by Monday 23 August to give them the vital protection provided by the vaccine before returning to school in September, the Health and Social Secretary Sajid Javid has announced today (15 August).

16 Aug 2021

Modeling the spread and development of SARS-CoV-2 outbreaks in the US

In a research paper recently uploaded to the medRxiv* preprint server, high-resolution contact data is utilized to characterize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in the USA, considering infections' mobility and seasonality and vaccination status seroprevalence within the population.

15 Aug 2021

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Researchers discuss the relationship between airway neutrophils and SARS-CoV-2 infection to determine the impact that neutrophils have on COVID-19.

15 Aug 2021

Utah warns of Delta variant eroding COVID vaccine effectiveness

A recent study finds a reduction in vaccine effectiveness against COVID-19 in Utah corresponding to the spread of the Delta variant in the region.

15 Aug 2021

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

A new study finds that human gut bacteria can induce antibodies of the immunoglobulin A (IgA) subtype that cross-react with the SARS-CoV-2 spike RBD.

15 Aug 2021

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Scientists with the Ajmera Transplant Centre at UHN have conducted a first-in-the-world randomized placebo-controlled trial of third dose COVID-19 booster vaccine for transplant patients that shows substantially improved protection.

14 Aug 2021

Enzyme acts as a sensor to find the hiding spots of viruses

While some types of RNA viruses cloak themselves to hide inside a cell and create copies of themselves, a "detective enzyme" might be attuned to their whereabouts. A slight variation in their genomic code gives some people's cells the capacity to produce this sensor.

14 Aug 2021

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

As COVID-19 booster shots begin for those with compromised immune systems, researchers at the UC Davis School of Medicine continue to collect data from clinical trial participants.

13 Aug 2021

L452R mutations may have triggered the emergence of several COVID-19 variants

Most of the recently risen coronavirus variants of interest or concern -- delta, kappa, epsilon, iota and lambda -- are universally carrying a mutation in amino acid L452 of the Spike protein that helps the virus bind to host cells.

13 Aug 2021

Study: 90% of children with ADHD continue to experience residual symptoms into young adulthood

Most children diagnosed with attention deficit hyperactive disorder (ADHD) don't outgrow the disorder, as widely thought.

13 Aug 2021

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Today, I signed CDC's Advisory Committee on Immunization Practices' (ACIP) recommendation that endorsed the use of an additional dose of COVID-19 vaccine for people with moderately to severely compromised immune systems after an initial two-dose vaccine series.

13 Aug 2021

Pfizer CEO to public: Just trust us on the covid booster

Pfizer CEO Albert Bourla was confident in June about the ability of his company's vaccine to protect against the highly contagious delta variant, as it marched across the globe and filled U.S. hospitals with patients.

13 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Research debunks myth that COVID vaccination promotes mutations

A study conducted by researchers at the University of Maryland, USA, has highlighted the importance of coronavirus disease 2019 (COVID-19) vaccination in reducing the frequency of mutations in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2021

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

In a new study, Chen-Yu Zhang's group from Nanjing University presents a rather striking finding that four circulating miRNAs, which are high in healthy people and much lower in older people and diabetic patients, could effectively inhibit SARS-CoV-2 replication by directly targeting the S protein.

12 Aug 2021

Nanotechnology may help improve treatment for colorectal cancer and melanoma

University of Arizona Health Sciences researchers recently completed a study that has the potential to improve cancer treatment for colorectal cancer and melanoma by using nanotechnology to deliver chemotherapy in a way that makes it more effective against aggressive tumors.

12 Aug 2021

UC San Diego scientists develop new method to keep cultured cells healthy

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

12 Aug 2021

immunity News and Research

Response to a third SARS-CoV-2 vaccine dose amongst immunocompromised

Researchers assess the genetic features of T-cell immunity development to SARS-CoV-2 variants

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

First dose of COVID-19 vaccine to be offered to all young people aged 16 to 17 in England

Modeling the spread and development of SARS-CoV-2 outbreaks in the US

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Utah warns of Delta variant eroding COVID vaccine effectiveness

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Enzyme acts as a sensor to find the hiding spots of viruses

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

L452R mutations may have triggered the emergence of several COVID-19 variants

Study: 90% of children with ADHD continue to experience residual symptoms into young adulthood

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Pfizer CEO to public: Just trust us on the covid booster

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Research debunks myth that COVID vaccination promotes mutations

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

Nanotechnology may help improve treatment for colorectal cancer and melanoma

UC San Diego scientists develop new method to keep cultured cells healthy

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