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Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Using fluvoxamine to treat COVID-19 patients reduces the need for prolonged hospitalization, trial shows

The results of a new randomized clinical trial, published in The Lancet Global Health, have demonstrated that using fluvoxamine to treat high-risk outpatients with early-diagnosed COVID-19 reduced the need for prolonged observation in an emergency setting or hospitalization, compared to a control group who received a placebo.

28 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021

Study: Younger and older patients with metastatic colorectal cancer survive for same amount of time

Even though young patients with metastatic colorectal cancer tend to be more fit and receive more intensive treatment than older patients, both groups survive for roughly the same amount of time, according to a new study by Dana-Farber Cancer Institute investigators.

27 Oct 2021

Promising new therapy for mesothelioma to enter a Phase I clinical trial

Linked to occupational asbestos exposure, malignant mesothelioma (MM) is an aggressive cancer arising primarily from the outer lining of the lungs with a dismal five-year survival rate of only five to 10 percent.

27 Oct 2021

SARS-CoV-2 infection leads to greater risk of neurological complications than vaccines

Researchers from across the UK, led by the University of Oxford, have today reported on the risks of developing neurological complications following a positive COVID-19 PCR test, or a first dose of either the Oxford-AstraZeneca or Pfizer-BioNTech COVID-19 vaccinations.

27 Oct 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

Northwestern scientists receive awards totaling nearly $18 million for Parkinson's disease research

Northwestern University scientists have received two awards totaling nearly $18 million for Parkinson's disease research from The ASAP Collaborative Research Network, a program of the Aligning Science Across Parkinson's (ASAP) initiative being implemented through The Michael J. Fox Foundation.

27 Oct 2021

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

In the worldwide effort to battle SARS-CoV-2, the virus that causes COVID-19, researchers have often turned to medications used as therapies for other conditions in the hopes of finding ones that either kill the coronavirus or lessen the impacts from its infection.

26 Oct 2021

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

A study conducted by a consortium of Brazilian researchers has demonstrated that a hyperimmune serum consisting of purified antibody fragments produced in horses may be an efficient approach to combat covid-19.

26 Oct 2021

Polyphenol-rich diet improves the intestinal permeability in older adults

The increase of intestinal permeability is associated with factors such as ageing, food allergies and intolerances and unhealthy diets.

26 Oct 2021

Clinical trial shows no benefit of tamoxifen in treating deadly fungal meningitis

Hopes that tamoxifen could improve survival for a deadly form of fungal meningitis have been dashed by clinical trial results published in eLife.

26 Oct 2021

New treatment for HPV-associated oropharynx cancer leads to excellent disease control, less side effects

Mayo Clinic researchers have found that a new, shorter treatment for patients with HPV-associated oropharynx cancer leads to excellent disease control and fewer side effects, compared to standard treatment.

26 Oct 2021

Intervention erases Black-white survival gaps in early-stage lung and breast cancer patients

A new study shows that system-level changes to the way cancer care is delivered can also eliminate Black-white disparities in survival from early-stage lung and breast cancer.

25 Oct 2021

CODA trial: Antibiotics now accepted as first-line treatment for people with appendicitis

Antibiotics are now an accepted first-line treatment for most people with appendicitis, according to final results of the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) trial, and an updated treatment guideline for appendicitis from the American College of Surgeons.

25 Oct 2021

Fewer, higher doses of post-prostatectomy radiation therapy does not increase long-term side effects

Using fewer - but higher - doses of radiation to treat men with prostate cancer who had their prostates removed does not increase long-term side effects or lower their quality of life compared to conventional radiation treatment, a new, multi-institutional clinical trial shows.

25 Oct 2021

Clinical Trial News and Research

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Using fluvoxamine to treat COVID-19 patients reduces the need for prolonged hospitalization, trial shows

New mechanisms for treating impregnable KRAS mutant cancers with statins

Study: Younger and older patients with metastatic colorectal cancer survive for same amount of time

Promising new therapy for mesothelioma to enter a Phase I clinical trial

SARS-CoV-2 infection leads to greater risk of neurological complications than vaccines

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Northwestern scientists receive awards totaling nearly $18 million for Parkinson's disease research

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

Polyphenol-rich diet improves the intestinal permeability in older adults

Clinical trial shows no benefit of tamoxifen in treating deadly fungal meningitis

New treatment for HPV-associated oropharynx cancer leads to excellent disease control, less side effects

Intervention erases Black-white survival gaps in early-stage lung and breast cancer patients

CODA trial: Antibiotics now accepted as first-line treatment for people with appendicitis

Fewer, higher doses of post-prostatectomy radiation therapy does not increase long-term side effects

Can targeting autophagy become a new approach to COVID-19 treatment?

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Vaccination data from Puerto Rico strongly supports COVID19 booster shots

Antidepressant offers no improvement in agitation for people with dementia, study shows

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