Membrane News and Research

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Botulinum toxins may cause remote effects by moving between neurons

The botulinum toxins are among the deadliest substances on Earth, and two specific toxins — including the popular drug Botox — have multiple uses for treating many neuromuscular conditions, including frown lines, disabling muscle spasms and migraine headaches.

5 Aug 2016

Penn researchers develop computer model for designing drug-delivery nanocarriers

A team of University of Pennsylvania researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body.

5 Aug 2016

Duke Health-led researchers identify new information about signaling mechanism of cells

Duke Health-led researchers have discovered new information about the signaling mechanism of cells that could one day help guide development of more specific drug therapies.

4 Aug 2016

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Research findings may have implications for ALS and other neurological disorders

Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe.

4 Aug 2016

Scientists fabricate smart second skin to protect soldiers from biological and chemical threats

In work that aims to protect soldiers from biological and chemical threats, a team of Lawrence Livermore National Laboratory scientists has created a material that is highly breathable yet protective from biological agents.

3 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.

30 Jul 2016

Scientists develop photosensitive mimics of class of signaling molecules

Teams at Ludwig-Maximilians-Universitaet in Munich and EMBL have created photosensitive mimics of a class of signaling molecules, thus enabling their actions to be regulated by light, and affording new insights into the communications networks that control cellular metabolism.

29 Jul 2016

MIT researchers develop portable device to manufacture biopharmaceuticals on demand

For medics on the battlefield and doctors in remote or developing parts of the world, getting rapid access to the drugs needed to treat patients can be challenging.

29 Jul 2016

Researchers identify reason why antidepressants take so long to work

An episode of major depression can be crippling, impairing the ability to sleep, work, or eat. In severe cases, the mood disorder can lead to suicide. But the drugs available to treat depression, which can affect one in six Americans in their lifetime, can take weeks or even months to start working.

29 Jul 2016

Researchers uncover novel virulence strategies employed by Leishmania parasite

Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite.

29 Jul 2016

Human immune system proteins can help combat chlamydia infections

Scientists from Federal Research and Clinical Centre of Physical-Chemical Medicine, Koltzov Institute of Developmental Biology and MIPT have shown that peptidoglycan recognition proteins (PGLYRPs) of the human immune system can play a key role in the fight against chlamydia infections. Their study was published in Infection and Immunity.

28 Jul 2016

New series of treatments may provide another option for families of unborn babies with CPAM

A medical team at Osaka University Hospital, Japan, has conducted successful treatment for the fetal lung disorder Congenital Pulmonary Airway Malformattion (CPAM), also known as Congenital Cystic Adenomatoid Malformation (CCAM).

28 Jul 2016

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial, making it one of the most common genetic causes of the disease, according to a paper published in Nature Genetics.

26 Jul 2016

Membrane News and Research

Botulinum toxins may cause remote effects by moving between neurons

Penn researchers develop computer model for designing drug-delivery nanocarriers

Duke Health-led researchers identify new information about signaling mechanism of cells

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Research findings may have implications for ALS and other neurological disorders

Scientists fabricate smart second skin to protect soldiers from biological and chemical threats

Researchers develop new hybrid method to study HIV protein involved in disease progression

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Researchers identify how precise control of inflammation could lead to bone repair

Scientists develop photosensitive mimics of class of signaling molecules

MIT researchers develop portable device to manufacture biopharmaceuticals on demand

Researchers identify reason why antidepressants take so long to work

Researchers uncover novel virulence strategies employed by Leishmania parasite

Human immune system proteins can help combat chlamydia infections

New series of treatments may provide another option for families of unborn babies with CPAM

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Scientists unveil structure of Zika NS1 protein

Researchers develop first placenta-on-a-chip to model interface between mother and fetus

Common drug for type 2 diabetes may play surprising role in preventing preterm birth

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