Central Nervous System News and Research

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Identification of gene in childhood kidney disease

An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS). Children with MKS have central nervous system deformities as well as abnormal cysts in their kidneys, and usually die shortly after birth.

16 Jan 2006

St. Jude projects 90 percent cure rate for acute lymphoblastic leukemia

The cure rate for the once almost universally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital.

11 Jan 2006

New pathways linking liver disease to changes in the central nervous system

Liver disease is often associated with "sickness behaviors," such as malaise, listlessness, anorexia, difficulty concentrating, and fatigue. In cholestatic liver diseases (where bile production is impaired) such as primary biliary cirrhosis, fatigue occurs in up to 86 percent of patients.

5 Jan 2006

Brain's endocannabinoids protects neurons from inflammation

Some clinical studies have indicated that marijuana or its active cannabinoid ingredient alleviates symptoms of the inflammatory disease multiple sclerosis (MS).

5 Jan 2006

Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

Infections are a major cause of childhood cancer

Results from a new study of childhood cancer statistics provide further evidence that common infections affecting mother and baby could play a key role in triggering certain types of the disease.

12 Dec 2005

New insights into pain mechanisms

Long treated as a side effect, pain is now widely recognized as an integral part of patient care.

7 Dec 2005

Hearing implants give best results when placed early

Investigators say that deaf children who are given cochlear implants before the age of 30 months are more able to combine what they hear and what they see than those who receive their implants when they are older.

6 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

Teenage suicides and Tamiflu - is there a link?

Roche the maker of the anti-flu drug Tamiflu has reported to authorities in Japan the possible suicides of two teenage boys although the company says there was no clear evidence that the drug had contributed to their deaths.

14 Nov 2005

Nerve-cell dendrites splice messenger RNA

Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger RNA (pre-mRNA), a process once believed to only take place in the nucleus of cells.

14 Nov 2005

Lupus discovery may improve treatment

Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment.

7 Nov 2005

Howard Hughes Medical Institute researchers have deciphered code for motor neuron wiring

Howard Hughes Medical Institute (HHMI) researchers have deciphered a key part of the regulatory code that governs how motor neurons in the spinal cord connect to specific target muscles in the limbs.

7 Nov 2005

Brain has more than one pathway along which visual information can be sent

Visual information can be processed unconsciously when the area of the brain that records what the eye sees is temporarily shut down, according to research at Rice University in Houston.

1 Nov 2005

Link between the act of lying and a significant increase in gastric arrhythmia

A new study suggests that changes in gastric physiology perform better than standard polygraph methods in distinguishing between lying and telling the truth.

1 Nov 2005

When it comes to telling lies it's the stomach not the heart which is the giveaway

According to a new study it is suggested that it is the stomach rather than the heart that offers greater lie detection accuracy.

31 Oct 2005

Gene involved in B-cell development might play a role in multiple sclerosis

The results of a large study published today in the open access journal BMC Neurology reveal that multiple sclerosis (MS) patients are more likely to carry two specific genetic variations in the Early B-cell factor gene (EBF-1), than healthy individuals.

30 Oct 2005