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Clinical utility of Roche assays determined utilizing samples from participants enrolled in a phase 2 trial of the mRNA-1273 vaccine

Researchers quantified the humoral immune response against the mRNA-1273 COVID-19 vaccine using commercially available high throughput assays.

17 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

Researchers compared the efficacy of booster doses of heterologous intramuscular and aerosolized adenovirus-vectored vaccine, a recombinant protein-based ZF2001 vaccine, and homologous CoronaVac vaccines.

17 Mar 2022

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.

17 Mar 2022

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Researchers assessed the safety profile and immunogenicity of a heterologous NVSI-06-08 boost against SARS-CoV-2 variants in individuals doubly vaccinated with the inactivated vaccine BBIBP-CorV.

17 Mar 2022

Frail and older males more vulnerable to COVID-19 than females

Researchers evaluated the association of biological sex, frailty, and age with the vaccine-elicited immunity against SARS-CoV-2.

17 Mar 2022

Antimicrobial resistance in COVID-19

Researchers discuss the impact of this extensive use of antibiotics on the rise of antimicrobial resistance.

16 Mar 2022

Study delineates how drug-induced changes of conscious awareness are rooted in neurotransmitter receptors

Psychedelics are now a rapidly growing area of neuroscience and clinical research, one that may produce much-needed new therapies for disorders such as depression and schizophrenia.

16 Mar 2022

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world.

16 Mar 2022

Study finds a promising new target for immunity-boosting cancer treatments

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a study from researchers at Weill Cornell Medicine and Albert Einstein College of Medicine.

16 Mar 2022

Yale researchers uncover how to control the blood-brain barrier with a molecule

The brain is composed of billions of neurons - vulnerable cells that require a protective environment to function properly.

16 Mar 2022

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

Some "hypervirulent" strains of Listeria monocytogenes have a greater capacity to infect the central nervous system.

16 Mar 2022

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Researchers identified curcumin derivatives as potential inhibitors of SARS-CoV-2 enzymes.

16 Mar 2022

Novel targets to inhibit SARS-CoV-2 variants

A new study identified additional targets on SARS-CoV-2 proteins to prevent the emergence of new SARS-CoV-2 variants of concern.

16 Mar 2022

Convalescent antibodies do not enhance SARS-CoV-2 infection

Researchers investigated whether antibodies enhance severe acute respiratory syndrome coronavirus-2 infection.

16 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Can cardiac biomarkers determine COVID-19 prognosis?

Researchers review prognostic cardiac biomarkers in COVID-19 patients.

15 Mar 2022

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers evaluate the feasibility of tonsil epithelial cell-derived organoids as an ex vivo model for studying SARS-CoV-2 infection.

15 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Receptor News and Research

Clinical utility of Roche assays determined utilizing samples from participants enrolled in a phase 2 trial of the mRNA-1273 vaccine

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Frail and older males more vulnerable to COVID-19 than females

Antimicrobial resistance in COVID-19

Study delineates how drug-induced changes of conscious awareness are rooted in neurotransmitter receptors

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

Study finds a promising new target for immunity-boosting cancer treatments

Yale researchers uncover how to control the blood-brain barrier with a molecule

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Novel targets to inhibit SARS-CoV-2 variants

Convalescent antibodies do not enhance SARS-CoV-2 infection

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Can cardiac biomarkers determine COVID-19 prognosis?

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers receive grant to find answers to taste loss in COVID patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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