Clinical Trial News and Research

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Portable PDT device could pave the way for at-home treatment of basal cell carcinoma

A new prototype photodynamic therapy (PDT) device that can be used at home significantly reduces pain levels during treatment of basal cell carcinoma (BCC), while achieving efficacy comparable with a hospital stay. These findings come from a breakthrough pilot study, presented today at the 30th EADV Congress.

1 Oct 2021

Aerobic exercise can help accelerate recovery after sport-related concussion in adolescents

Adolescents can speed their recovery after a sport-related concussion and reduce their risk of experiencing protracted recovery if they engage in aerobic exercise within 10 days of getting injured, according to a new University at Buffalo study.

1 Oct 2021

Study finds racial/ethnic disparities in survival of patients with childhood cancers in the U.S

A new study finds racial/ethnic disparities in survival among newly diagnosed patients with childhood cancers in the United States and that area-level socioeconomic status (SES) and health insurance contribute to these disparities.

1 Oct 2021

Damaging DNA builds up in the eyes to drive blinding age-related macular degeneration

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals.

1 Oct 2021

Additional supportive care services benefit older adults receiving chemotherapy, study finds

A clinical trial led by researchers at City of Hope, a world-renowned cancer research and treatment organization, showed that patients over 65 receiving chemotherapy experienced significantly fewer treatment-related side effects when a multidisciplinary team of experts analyzed each case and introduced personalized interventions.

30 Sep 2021

Moderna vaccine reduced viral load and protected against SARS-CoV-2 variants in new phase 3 trial

Coronavirus research has shown that higher viral loads are associated with severe COVID-19 infection. But new results from the phase III Coronavirus Efficacy (COVE) clinical trial find the Moderna vaccine reduces severe acute respiratory coronavirus 2 (SARS-CoV-2) viral load and viral shedding.

30 Sep 2021

Virtual care with remote automated monitoring can improve outcomes after non-elective surgery

Patients using take-home technology following non-elective surgery resulted in significantly greater detection and correction of drug errors, and reduction in patients' pain, says a national study led by Hamilton researchers.

30 Sep 2021

Researchers develop novel antibacterial material for wound dressing

Researchers at the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Technical University of Liberec in collaboration with researchers from the Institute of Microbiology of the CAS, the Department of Burns Medicine of the Third Faculty of Medicine at Charles University (Czech Republic), and P. J. Šafárik University in Košice (Slovakia) have developed a novel antibacterial material combining nonwoven nanotextile and unique compounds with antibacterial properties.

30 Sep 2021

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Mark Bear, Picower Professor of Neuroscience at MIT, recalls the "eureka moment" 20 years ago when he realized that a severe developmental brain disorder - fragile X syndrome - might be treated with drugs that inhibit a neurotransmitter receptor called mGluR5.

29 Sep 2021

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

A new approach to 'prime' the tumor environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer.

29 Sep 2021

A review of COVID-19 vaccine effectiveness

A new study systematically reviews vaccine efficacy and vaccine effectiveness (VE) of COVID-19 vaccines.

29 Sep 2021

Psychological treatment provides potent and durable relief for chronic back pain, study finds

Rethinking what causes pain and how great of a threat it is can provide chronic pain patients with lasting relief and alter brain networks associated with pain processing, according to new University of Colorado Boulder-led research.

29 Sep 2021

New facility established for testing innovative health nanotechnologies

A bespoke nationwide facility for testing innovative nanotechnologies for healthcare applications is to be established at the University of Strathclyde.

29 Sep 2021

Combination of two drugs may help pancreatic and liver cancer patients

A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.

29 Sep 2021

Greater viral load of SARS-CoV-2 variants of concern increases transmission potential

By quantifying the probability of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in accordance with its viral load after a high-risk contact, researchers from France, Spain, and the United Kingdom show a substantial correlation of transmission probability and viral load increase in variants of concern.

28 Sep 2021

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease.

28 Sep 2021

Clinical study tests novel topical corneal epithelial stem cell-derived product for treating dry eye disease

Several studies conducted over the last decade have concluded that dry eye disease (DED) affects up to 50% of the U.S. population, creating a liability for the nation's health care system that is estimated to exceed $50 billion annually.

28 Sep 2021

Novel mind-body intervention found to be highly beneficial for treating chronic back pain

Chronic back pain is the leading cause of disability worldwide. In the United States, patients spend up to $300 billion each year to treat the condition, according to a 2012 study published in the Journal of Pain.

28 Sep 2021

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Kristina Simonyan, MD, PhD, Dr med, director of laryngology research at Mass Eye and Ear, has been awarded an $11.9 million P50 Clinical Research Center Grant from the National Institute on Deafness and Other Communicable Disorders of the National Institute of Health to form a new multidisciplinary center across four academic medical institutions that will be committed to conducting research on laryngeal dystonia and voice tremor, two debilitating neurological voice disorders.

28 Sep 2021

Researchers release guidance to address pathology aspects in clinical trial protocols

An international group of cancer researchers, led by the National Cancer Research Institute's (NCRI) Cellular Molecular Pathology Initiative (CMPath), has published guidance to address the variability in how pathology is planned and delivered in clinical trials.

28 Sep 2021

Clinical Trial News and Research

Portable PDT device could pave the way for at-home treatment of basal cell carcinoma

Aerobic exercise can help accelerate recovery after sport-related concussion in adolescents

Study finds racial/ethnic disparities in survival of patients with childhood cancers in the U.S

Damaging DNA builds up in the eyes to drive blinding age-related macular degeneration

Additional supportive care services benefit older adults receiving chemotherapy, study finds

Moderna vaccine reduced viral load and protected against SARS-CoV-2 variants in new phase 3 trial

Virtual care with remote automated monitoring can improve outcomes after non-elective surgery

Researchers develop novel antibacterial material for wound dressing

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

A review of COVID-19 vaccine effectiveness

Psychological treatment provides potent and durable relief for chronic back pain, study finds

New facility established for testing innovative health nanotechnologies

Combination of two drugs may help pancreatic and liver cancer patients

Greater viral load of SARS-CoV-2 variants of concern increases transmission potential

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Clinical study tests novel topical corneal epithelial stem cell-derived product for treating dry eye disease

Novel mind-body intervention found to be highly beneficial for treating chronic back pain

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Researchers release guidance to address pathology aspects in clinical trial protocols

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