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New data from descriptive sub-analysis of patients with compensated liver cirrhosis

New data from a descriptive sub-analysis of patients with compensated liver cirrhosis show that up to 43 percent of genotype-1a (GT1a) and up to 71 percent of GT1b hepatitis C virus (HCV) patients achieved sustained viral response (SVR12). SVR12 has been highly correlated with SVR24, which is a recognized indicator of viral cure.

20 Apr 2012

Viewpoints: Bishops find fault with GOP budget; Pelosi on court's role in health law

In February, the Catholic Church attempted to impose its opposition to birth control on its employees, upsetting Democrats and the left. This week, the Church is criticizing Republicans, acting in the highest tradition of its social mission by speaking out against spending cuts on programs for the poor.

20 Apr 2012

Regenerative medicine research offers hope for the blind

The University College London researchers transplanted immature vision cells directly into the mouse retina. They noted that within weeks the cells began to integrate into the retina and the researchers, led by Prof Robin Ali in the university’s Institute of Ophthalmology, were able to show that vision began to return to the mice.

19 Apr 2012

Inform Genomics completes first phase in oral mucositis risk prediction study

Inform Genomics, Inc., a private company focused on developing novel platforms of personalized medicine products for cancer supportive care and inflammatory diseases, today announced the completion of the first phase of product development to predict a patient's risk of developing oral mucositis after receiving high dose chemotherapy prior to hematopoietic stem cell transplant.

19 Apr 2012

Autologous BMMNCs reduce vascular growth in patients with diabetes

Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes.

19 Apr 2012

Tengion completes FDA Pre-IND meeting for Neo-Kidney Augment preclinical program

Tengion, Inc., a leader in regenerative medicine, today announced that it recently completed a successful Pre-IND meeting with the U.S. Food and Drug Administration (FDA) for its lead preclinical program, the Neo-Kidney Augment.

18 Apr 2012

Combined, complimentary therapies maximize NSC transplantation benefits for spinal cord repair

Combined, complimentary therapies have the ability to maximize the benefits of neural stem cell (NSC) transplantation for spinal cord repair in rat models, according to a study carried out by a team of Korean researchers who published in a recent issue of Cell Transplantation.

18 Apr 2012

UTHealth researcher studies novel cell therapy to prevent GVHD

A researcher at The University of Texas Health Science Center at Houston (UTHealth) is studying a novel cell therapy that could help avoid autoimmune problems after stem cell transplantation, as well as potentially treat other autoimmune diseases.

17 Apr 2012

TGF-β molecule ramps up the immune system in some cases and suppress it in others

Loyola researchers are reporting surprising findings about a molecule that helps ramp up the immune system in some cases and suppress it in others.

16 Apr 2012

SMART Heart improves cardiovascular surgical outcomes

Two years ago, 57-year-old Allus Brown underwent a simultaneous heart-kidney transplant and spent months in and out of the hospital after battling dilated cardiomyopathy, a condition that enlarges and weakens the heart. Now fully recovered, Brown is still in and out of Northwestern Memorial Hospital's Bluhm Cardiovascular Institute each week. Only nowadays when he visits, he's laughing it up, playing board games, and sharing accounts of his own struggles with heart disease as part of the Bluhm Institute's new and innovative program, SMART Heart, stress management and recreational therapy for heart patients.

16 Apr 2012

FDA approves HUD designation for SynCardia temporary Total Artificial Heart for destination therapy

SynCardia Systems, Inc., manufacturer of the world's first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart, announced today that the U.S. Food and Drug Administration has approved a Humanitarian Use Device (HUD) designation for the SynCardia temporary Total Artificial Heart to be used for destination therapy in addition to its current PMA approval as a bridge to transplant.

12 Apr 2012

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

International study that included St. Jude Children's Research Hospital reports some young acute lymphoblastic leukemia patients who fail induction therapy can achieve high cure rates without bone marrow transplantation.

12 Apr 2012

Researchers discover a lead on the origin of chronic lymphatic leukaemia

Up until now the causes of the development of chronic lymphatic leukaemia, the most common form of cancer of the blood in Europe, have been unknown. At present a cure is not possible. A research group at the MedUni Vienna led by Christoph Steininger of the University Department of Internal Medicine I has now however discovered a lead on the origin of this disease. Says Steiniger: "This could influence the therapy approach taken in treating chronic lymphatic leukaemia."

12 Apr 2012

FDA selects three renal device projects for new Pathway program

A UCSF-led effort to create an implantable artificial kidney for dialysis patients has been selected as one of the first projects to undergo more timely and collaborative review at the Food and Drug Administration.

10 Apr 2012

Top ten facts about organ and tissue donation

Every year, more than 100,000 Americans will need a life-saving organ transplant, yet in 2011 fewer than 22,000 transplants took place in the United States. In New York only 18 percent of New Yorkers who are eligible to donate are registered as organ donors, in stark contrast to the national average of 42 percent.

10 Apr 2012

Proteonomix provides corporate and clinical trial updates

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today provided updates on its progress.

10 Apr 2012

Higher blood glucose levels may improve survival rates for heart failure patients with diabetes

Lowering glucose levels for people with diabetes is normally critical to improving health outcomes. But for those with heart failure, that might not always be the case, say UCLA researchers.

10 Apr 2012

Study explores link between intraoperative blood loss and pediatric patients' underlying condition

The relative risk of blood loss during corrective spine surgery in children appears linked to the underlying condition causing the spinal deformity, according to a new study from Johns Hopkins Children's Center.

7 Apr 2012

Regeneron, Sanofi announce clinical and regulatory update for ZALTRAP

Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Priority Review of the Biologics License Application (BLA) for the investigational agent ZALTRAP (aflibercept) concentrate for solution for infusion in combination with the irinotecan-fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer (mCRC) previously treated with an oxaliplatin-containing regimen.

6 Apr 2012

Majority of female kidney failure patients on dialysis may experience sexual problems

The vast majority of female kidney failure patients on dialysis may experience sexual problems, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Additional studies are needed to understand how sexual dysfunction affects dialysis patients' quality of life and psychological wellbeing.

6 Apr 2012

Transplant News and Research

New data from descriptive sub-analysis of patients with compensated liver cirrhosis

Viewpoints: Bishops find fault with GOP budget; Pelosi on court's role in health law

Regenerative medicine research offers hope for the blind

Inform Genomics completes first phase in oral mucositis risk prediction study

Autologous BMMNCs reduce vascular growth in patients with diabetes

Tengion completes FDA Pre-IND meeting for Neo-Kidney Augment preclinical program

Combined, complimentary therapies maximize NSC transplantation benefits for spinal cord repair

UTHealth researcher studies novel cell therapy to prevent GVHD

TGF-β molecule ramps up the immune system in some cases and suppress it in others

SMART Heart improves cardiovascular surgical outcomes

FDA approves HUD designation for SynCardia temporary Total Artificial Heart for destination therapy

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

Researchers discover a lead on the origin of chronic lymphatic leukaemia

FDA selects three renal device projects for new Pathway program

Top ten facts about organ and tissue donation

Proteonomix provides corporate and clinical trial updates

Higher blood glucose levels may improve survival rates for heart failure patients with diabetes

Study explores link between intraoperative blood loss and pediatric patients' underlying condition

Regeneron, Sanofi announce clinical and regulatory update for ZALTRAP

Majority of female kidney failure patients on dialysis may experience sexual problems

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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