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New evidence shows how fever alters immune cells

Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how.

16 Jan 2019

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

The Staphylococcus aureus bacterium is one of the commonest pathogens and can even cause sepsis. The new antibiotic dalbavancin is very effective against many bacterial pathogens.

10 Jan 2019

New strategy may prevent spread of drug resistance

Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems.

10 Jan 2019

Bacteria on the International Space Station are adapting to survive, not to harm

Mutant bacteria stranded in space by visiting astronauts have been adapting to survive in their new environment, according to a new study.

10 Jan 2019

Viral replication not necessary to cause lethal disease by food-borne pathogen

The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli, according to a study published January 10 in the open-access journal PLOS Pathogens by Sowmya Balasubramanian, John Leong and Marcia Osburne of Tufts University School of Medicine, and colleagues.

10 Jan 2019

New bacteria discovered in the blood of human patients

Two new species of bacteria have been found in the blood of patients in China.

10 Jan 2019

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Specific respiratory microbiome communities may be linked to influenza susceptibility, according to a study published January 9, 2019 in the open-access journal PLOS ONE by Betsy Foxman from the University of Michigan, USA, and colleagues

10 Jan 2019

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

The hygiene hypothesis may explain why asthma and other allergic airway diseases have dramatically increased over the past decades in industrialized countries.

9 Jan 2019

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Using a unique bioinformatics technique developed at the University of Alabama at Birmingham, UAB researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery.

9 Jan 2019

UC San Diego to conduct first U.S. clinical trial of intravenously administered bacteriophage therapy

The U.S. Food and Drug Administration has accepted an Investigational New Drug application by physician-scientists at University of California San Diego School of Medicine to conduct the first U.S. clinical trial of an intravenously administered bacteriophage-based therapy.

9 Jan 2019

Scientists explore bacterial immunity to better understand infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death.

8 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

Study confirms increased pneumonia risk with prescription opioids

A study led by researchers at Yale University has shown that taking prescribed opioids increases the risk of pneumonia, irrespective of HIV status.

7 Jan 2019

Common food additive could cause celiac disease, review says

Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods.

7 Jan 2019

Nature-based antibiotic molecules for treatment of infections

New developments in antimicrobial peptides (AMPs) with antibiofilm properties are rapidly materializing.

2 Jan 2019

Higher vitamin C intake crucial for metabolic syndrome patients to halt cycle of antioxidant disruption

A higher intake of vitamin C is crucial for metabolic syndrome patients trying to halt a potentially deadly cycle of antioxidant disruption and health-related problems, an Oregon State University researcher says.

2 Jan 2019

Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability

If you live in the United States, you are unlikely to come into contact with the microbe that causes tuberculosis. Your odds of encountering the microbe are so low, in fact, that risk factors for the disease can easily go unnoticed: If you happened to carry a gene that predisposed you to tuberculosis, you likely wouldn't know.

2 Jan 2019

Scientists solve mystery of Yemen cholera epidemic

The most likely source of the cholera epidemic in Yemen has been discovered by scientists. Through the use of genomic sequencing, scientists at the Wellcome Sanger Institute and Institut Pasteur estimate the strain of cholera causing the current outbreak in Yemen - the worst cholera outbreak in recorded history - came from Eastern Africa and entered Yemen with the migration of people in and out of the region.

2 Jan 2019

Bacterial News and Research

New evidence shows how fever alters immune cells

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

New strategy may prevent spread of drug resistance

Bacteria on the International Space Station are adapting to survive, not to harm

Viral replication not necessary to cause lethal disease by food-borne pathogen

New bacteria discovered in the blood of human patients

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

UC San Diego to conduct first U.S. clinical trial of intravenously administered bacteriophage therapy

Scientists explore bacterial immunity to better understand infectious disease

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Study confirms increased pneumonia risk with prescription opioids

Common food additive could cause celiac disease, review says

Nature-based antibiotic molecules for treatment of infections

Higher vitamin C intake crucial for metabolic syndrome patients to halt cycle of antioxidant disruption

Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability

Scientists solve mystery of Yemen cholera epidemic

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