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When does occasional absentmindedness signal the start of memory decline?

Forgetfulness is something everyone experiences at one time or another, but at what point does it indicate the beginning of a serious memory loss?

17 Feb 2005

Programmed cell death may provide clues to cancer and autoimmune diseases therapies

Dartmouth Medical School geneticists have found links in the cell death machinery of worms and mammals, opening new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases.

16 Feb 2005

Bionomics goes for aggressive strategy in 2005

Australian biotech, Bionomics gave an investor presentation in Melbourne on 2 February 2005 and outlined a bolder, more aggressive strategy. There are many Australian biotech companies with big aspirations.

13 Feb 2005

Ingestion of afterbirth appears to promote maternal behavior in mammals

A behavioral neuroscientist at the University at Buffalo holds that the ingestion of afterbirth by a mother, a feature of pregnancy in nearly all non-human mammals, not only relieves postpartum pain, but optimizes the onset of maternal behavior by mediating the activity of specific opioid activity circuits in the brain.

13 Feb 2005

Sex hormone progesterone metabolite allopregnanolone reduces stress

A steroid hormone released during the metabolism of progesterone, the female sex hormone, reduces the brain's response to stress, according to research in rats by scientists at Emory University School of Medicine, the Yerkes National Primate Research Center and Atlanta's Center for Behavioral Neuroscience.

9 Feb 2005

Research confirms how early-life events shape later physiology

Underscoring the value of good prenatal care, new research suggests that early infection may create a cognitive vulnerability that appears later during stress on the immune system.

8 Feb 2005

Eleventh Edition of the Report on Carcinogens

The Department of Health and Human Services released its Eleventh Edition of the Report on Carcinogens today, adding seventeen substances to the growing list of cancer-causing agents, bringing the total to 246.

31 Jan 2005

Organon’s compound, Org 24448, selected to test efficacy of cognitive dysfunction in schizophrenia

The National Institute of Mental Health (NIMH) sponsored network called Treatment Units for Research on Neurocognition in Schizophrenia (TURNS) has selected Organon’s compound, Org 24448, to undergo testing as part of its effort to facilitate the development of medications to enhance cognition in patients with schizophrenia.

24 Jan 2005

Insight into potential mechanisms underlying type II diabetes

New research published in the premier issue of Cell Metabolism finds that a single brain region is sufficient for normal control of blood sugar and activity level by the fat hormone leptin. The same region also exerts significant, though more modest, control over leptin's effects on body weight.

19 Jan 2005

Psychiatric disorders detected using blood test

ChondroGene Limited reported today that a paper entitled "Assessing the Validity of Blood- Based Gene Expression Profiles for the Classification of Schizophrenia and Bipolar Disorder: A preliminary Report" is available online on the American Journal of Medical Genetics Part B: Neuropsychiatric Genetics' website.

19 Jan 2005

Lifting weights can help people with multiple sclerosis

Lifting weights can improve muscle strength and quality of life for people afflicted with the degenerative disease multiple sclerosis, a new University of Florida study finds.

17 Jan 2005

Researchers have identified the cellular receptor for the JC virus

Researchers funded in part by the National Institute of Neurological Disorders and Stroke (NINDS) have identified the cellular receptor for the JC virus, which causes the fatal neurological disease progressive multifocal leukoencephalopathy (PML).

17 Jan 2005

Latest Canadian mad cow case poses no threat

The recently confirmed case of mad cow disease in Canada is an isolated case and does not represent a threat to the food chain, according to the Pan American Health Organization’s top expert on the issue.

12 Jan 2005

Escalating demand for novel and effective therapeutic approaches underlines growing appeal of peptides

With a 30 per cent revenue share, Europe trails the United States as the second largest regional market for therapeutic peptides. The rising need for new therapeutic approaches combined with the potential of peptides as active pharmaceutical ingredients for effective drug formulation is contributing to rapid market development.

12 Jan 2005

Scientists identify a protein that regulates alcohol-withdrawal seizures

Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the substance in beer, wine and liquor that is addictive, leads to changes in the brain.

10 Jan 2005

Restless legs syndrome is underdiagnosed in kids

A new Mayo Clinic study has for the first time established rates of restless legs syndrome in children, finding that almost 6 percent of children seen in Mayo's sleep clinic have the disease.

28 Dec 2004

Paclitaxel may benefit Alzheimer's and Parkinson's movement disorders

Angiotech Pharmaceuticals have announced that a preclinical study published in today's early edition of the Proceedings of the National Academy of Sciences highlights the positive effects of Paxceed on movement disorders commonly seen in diseases known as taupathies, such as Alzheimer's and Parkinson's.

27 Dec 2004

FDA approves Enablex for the treatment of overactive bladder

Novartis Pharmaceuticals Corporation today announced that the U.S. Food and Drug Administration (FDA) has approved Enablex® (darifenacin) extended-release tablets (7.5mg and 15mg) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency.

22 Dec 2004

Turning off cell suicide switch fails to stop prion damage

Researchers knew that prions, the misfolded proteins that cause mad cow disease and other brain disorders, were killing off a class of important brain cells in a transgenic mouse model. But when they found a way to rescue those cells, they were astonished to discover the mice still became sick.

21 Dec 2004

DLX5 gene may play a role in the pathology of Rett Syndrome

A research team led by Terumi Kohwi-Shigematsu of the Life Sciences Division of Lawrence Berkeley National Laboratory has identified a gene, DLX5, that may play a role in the pathology of Rett Syndrome, a devastating neurological disorder diagnosed almost exclusively in girls.

20 Dec 2004