Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Amgen (NASDAQ: AMGN) today announced that the Phase 3 TESLA (Trial Evaluating PCSK9 Antibody in Subjects with LDL Receptor Abnormalities) trial evaluating evolocumab met its primary endpoint of the percent reduction from baseline at week 12 in low-density lipoprotein cholesterol (LDL-C).

19 Mar 2014

Non-alcoholic steatohepatitis (NASH): an interview with Jean-François Mouney, CEO of Genfit

The progressive form of Non-Alcoholic Fatty Liver Disease (NAFLD) is Non-Alcoholic Steatohepatitis (NASH), which defines a subgroup of NAFLD where liver steatosis co-exists with cell injury (hepatocyte ballooning) and inflammation with or without fibrosis at histological examination.

18 Mar 2014

Study: Identifying biomarkers could lead to earlier detection of preeclampsia

Identifying biomarkers could lead to earlier detection of preeclampsia, which in turn can lead to healthier mothers and children, according to a collaborative study from the Centre of Molecular Inflammation Research (CEMIR) and the MR Cancer Group at the Norwegian University of Science and Technology (NTNU).

18 Mar 2014

Hemp flour with decaffeinated green tea leaves could be used to develop gluten-free snack cracker

The market for gluten-free foods with functional properties is growing immensely across virtually all food categories on a global level. The need to replace wheat proteins, fibers, and minerals is very important in order to provide a better selection and more nutritious food for consumers that belong to this segment of the population.

18 Mar 2014

Research on diverse health benefits of oats in protecting heart

Eleven top scientists from around the globe presented the latest findings on the powerful compounds found in oats in a scientific session titled, Physicochemical Properties and Biological Functionality of Oats, at the 247th Annual Conference of the American Chemical Society in Dallas, TX

17 Mar 2014

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

As long as inexpensive statins, which lower cholesterol, are readily available and patients don't mind taking them, it doesn't make sense to do a heart scan to measure how much plaque has built up in a patient's coronary arteries before prescribing the pills, according to a new study by researchers at UC San Francisco.

17 Mar 2014

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

17 Mar 2014

Investigators urge drug regulators to provide clear evidence on statins’ side effects

At a time when the wider prescription of statins is under renewed public scrutiny, a substantial analysis of placebo-controlled randomised trials of statins has found that only a small minority of side effects reported by those taking the cholesterol-lowering drugs are actually attributable to them.

13 Mar 2014

Galmed Pharmaceuticals prices initial public offering of 2,837,400 shares

Galmed Pharmaceuticals Ltd. ("Galmed") today announced the pricing of its initial public offering of 2,837,400 ordinary shares at a public offering price of $13.50 per share, before underwriting discounts and commissions.

13 Mar 2014

People with prehypertension more likely to develop stroke

Anyone with blood pressure that's higher than the optimal 120/80 mmHg may be more likely to have a stroke, according to a new meta-analysis published in the March 12, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Mar 2014

Patient with autistic behavior experiences improvements in mental health after liver transplant

A patient with a rare metabolic disease that causes liver failure and autistic behavior experienced significant improvements in both her physical and mental health after receiving a liver transplant, according to a new case report published in the American Journal of Transplantation.

12 Mar 2014

MedVantx MedStart Connect program increases patient initiation of new prescriptions

New research presented today at the World Congress Summit to Improve Adherence and Enhance Patient Engagement by researchers from the University of Pittsburgh School of Pharmacy, finds that a unique generic medication sampling program, the MedVantx MedStart™ Connect program, implemented in the primary care physicians' office, led to significantly increased patient initiation of new prescriptions (primary adherence) as well as continued use of the medications (secondary adherence), and could possibly lead to savings for health plans.

11 Mar 2014

Statins combined with conventional blood clot prevention therapies, reduce VTE risk by 48%

Statins have long been known to lower cholesterol and, more recently, to decrease the risk of deep vein thrombosis (blood clots) in healthy, non-surgical patients.

11 Mar 2014

Family CV history indicates intensive treatment need for hypertensive patients

A family history of premature cardiovascular disease is a marker of increased mortality risk in patients with hypertension, report researchers.

10 Mar 2014

RIT plans for new school of health and nutrition to promote healthy lifestyles

Rochester Institute of Technology today announced plans for a new school of health and nutrition, charged with educating students on the role of nutrition, exercise and behavior modification in promoting healthy lifestyles.

10 Mar 2014

Peanut consumption offers significant benefits to people with elevated serum lipids and blood pressure

A new study just released in the American Journal of Clinical Nutrition found that different flavors of peanuts – salted, spicy, honey-roasted, or unsalted – result in positive health benefits. The study, "A Randomized Trial on the Effects of Flavorings on the Health Benefits of Daily Peanut Consumption," was conducted at Purdue University and included over 150 men and women who incorporated peanuts into their daily diet for 12 weeks.

10 Mar 2014

Research explores new diagnostic strategies to detect glaucoma

Research exploring several new diagnostic strategies to find the earliest changes in the eye to detect glaucoma is underway at the University of Alabama at Birmingham School of Optometry. One optometrist says awareness of this eye disorder is just as important as continuing to study it.

7 Mar 2014

Researchers examine association between diabetes and obesity

It's by now well established that obesity is a major risk factor for diabetes. But what exactly is it about extra body fat that leads to insulin resistance and blood glucose elevation, the hallmarks of diabetes?

7 Mar 2014

Boston Heart Diagnostics announces commercial launch of FDA-cleared MPO test

Boston Heart Diagnostics Corporation, a pioneer in integrating next-generation diagnostics into personalized nutrition and lifestyle programs for patients with or at risk for heart disease, announced the commercial launch of an FDA-cleared MPO (myeloperoxidase) test, a key biomarker for inflammation. Studies show that MPO levels are useful predictors of near-term (one to six months) risk of heart attack or stroke.

6 Mar 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Safeguard Scientifics, Inc. today announced fourth quarter and full-year 2013 financial results. For the three months ended December 31, 2013, Safeguard's net income was $24.0 million, or $1.10 per share, compared to net loss of $10.8 million, or $0.51 per share for the same period in 2012. For the year ended December 31, 2013, Safeguard's net loss was $35.5 million, or $1.66 per share, compared to $39.4 million, or $1.88 per share for the same period in 2012.

6 Mar 2014

Cholesterol News and Research

Further Reading

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Non-alcoholic steatohepatitis (NASH): an interview with Jean-François Mouney, CEO of Genfit

Study: Identifying biomarkers could lead to earlier detection of preeclampsia

Hemp flour with decaffeinated green tea leaves could be used to develop gluten-free snack cracker

Research on diverse health benefits of oats in protecting heart

Researchers create statistical model to predict whether heart scans are useful in prescribing statins

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Investigators urge drug regulators to provide clear evidence on statins’ side effects

Galmed Pharmaceuticals prices initial public offering of 2,837,400 shares

People with prehypertension more likely to develop stroke

Patient with autistic behavior experiences improvements in mental health after liver transplant

MedVantx MedStart Connect program increases patient initiation of new prescriptions

Statins combined with conventional blood clot prevention therapies, reduce VTE risk by 48%

Family CV history indicates intensive treatment need for hypertensive patients

RIT plans for new school of health and nutrition to promote healthy lifestyles

Peanut consumption offers significant benefits to people with elevated serum lipids and blood pressure

Research explores new diagnostic strategies to detect glaucoma

Researchers examine association between diabetes and obesity

Boston Heart Diagnostics announces commercial launch of FDA-cleared MPO test

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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