Efficacy News and Research

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Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

A case for updating COVID vaccines with beta variant spike sequences

A recent Nature Communications study has discussed preclinical and clinical data on COVID-19 vaccine antigens that could be utilized to develop effective booster vaccines.

3 Oct 2022

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

Researchers investigated the use of aminoadamantane nitrate compounds as anti-SARS-CoV-2 drugs.

3 Oct 2022

Preventive malaria treatment is a cost-effective strategy for saving young lives

Young children in sub-Saharan Africa often become severely anaemic as consequence of a malaria infection. Treating them requires blood transfusions and they must stay hospitalized for several days.

3 Oct 2022

Does high vaccine coverage among the adult population grant the unvaccinated younger population indirect protection against SARS-CoV-2?

Researchers investigated whether the mass vaccination of the adult population of Schwaz, Austria, against SARS-CoV-2 conferred an indirect protective effect on the proportion of unvaccinated children in the population.

3 Oct 2022

COVID-19 vaccination offers sustained and potent neutralizing protection against variants compared to natural infection

In a new study, researchers assessed the immunoglobulin (Ig)-G responses to SARS-CoV-2 after natural infection or vaccination.

3 Oct 2022

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

Researchers evaluated the efficacy, immunogenicity, and safety of a novel SARS-CoV-2 linear deoxyribonucleic acid vaccine in ferret models delivered using intramuscular injection and electroporation.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Vaccine effectiveness of a second mRNA COVID-19 vaccine booster among nursing home residents

Researchers compared the effectiveness of double booster SARS-CoV-2 mRNA vaccinations and single booster vaccinations among nursing home residents in the US.

3 Oct 2022

Universal vaccine advancement through AI and recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng and Dr. Lurong Pan about how AI computing can be used in combination with high throughput production and screening to enhance the development process for potential universal vaccines.

From Sino Biological Inc. 3 Oct 2022

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

A recent Nature Reviews Immunology study has summarized the efficacy of neutralizing antibodies that target four main regions of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), namely, the receptor-binding domain (RBD) in the S1 subunit, the fusion peptide region in the S2 subunit, the stem helix region, and the N-terminal domain.

2 Oct 2022

IRIS Registry presents latest eye research at AAO 2022

The IRIS Registry (Intelligent Research in Sight) powered several big data studies this year, most of which will be presented and discussed at AAO 2022 Gather, the 126th annual meeting of the American Academy of Ophthalmology.

30 Sep 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

Burt's Bees research shows the benefits of nature-based regimens to protect and restore skin health

Burt's Bees, the #1 dermatologist recommended natural skin care brand and a pioneer in this area, announced its latest research findings on the benefits of nature-based regimens to protect and restore skin health across various skin conditions, types, and tones.

30 Sep 2022

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

In a new study, researchers investigated the efficacy of curcumin as a blue light photosensitizing agent for photodynamic therapy (PDT), as a prophylactic agent, and as a therapeutic agent against SARS-CoV-2.

30 Sep 2022

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

A new study demonstrated the efficacy of a newly engineered angiotensin-converting enzyme 2 (ACE2) based immunoadhesin against Omicron and other SARS-CoV-2 VOCs.

30 Sep 2022

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell entry. The study has recently been published in the journal Food and Chemical Toxicology.

29 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for complications when hospitalized.

29 Sep 2022

Efficacy News and Research

Spike-specific memory B cells develop resilience to SARS-CoV-2

A case for updating COVID vaccines with beta variant spike sequences

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

Preventive malaria treatment is a cost-effective strategy for saving young lives

Does high vaccine coverage among the adult population grant the unvaccinated younger population indirect protection against SARS-CoV-2?

COVID-19 vaccination offers sustained and potent neutralizing protection against variants compared to natural infection

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Vaccine effectiveness of a second mRNA COVID-19 vaccine booster among nursing home residents

Universal vaccine advancement through AI and recombinant technology

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

IRIS Registry presents latest eye research at AAO 2022

The compositional and functional diversity of the gut fungal microbiome

Burt's Bees research shows the benefits of nature-based regimens to protect and restore skin health

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

Study reveals the role of autophagy in competitive elimination of cancer cells

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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