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Are you and your primary care doc ready to talk about your DNA?

If you have a genetic mutation that increases your risk for a treatable medical condition, would you want to know? For many people the answer is yes. But such information is not commonly part of routine primary care.

22 May 2018

Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

A rare genetic disorder in which people are suddenly overcome with profound muscle weakness is caused by a hole in a membrane protein that allows sodium ions to leak across cell membranes, researchers at the University of Washington School of Medicine in Seattle have found.

21 May 2018

HCM mutation prevents the heart from increasing pumping force, study shows

Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy (HCM) disrupts the heart's normal function.

21 May 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

Gene therapy that reverses blindness in dogs could also help treat humans

A Michigan State University veterinary ophthalmologist has modified a gene therapy that reverses blindness in dogs that have a certain form of a disease known as progressive retinal atrophy, or PRA, and is now looking to advance the treatment for human use.

18 May 2018

Raising Awareness of Childhood Dementia

The Dementia Strikes Children Too campaign aims to raise awareness of childhood dementia, drive for better clinical education of this group of diseases, and put in place the systems and tools for earlier diagnosis.

18 May 2018

Ovarian cancer therapy may help treat patients with aggressive pancreatic cancer

A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options.

18 May 2018

Pancreatic cancer patients with BRCA1 or BRCA2 mutations fare better on platinum-based chemotherapy

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

17 May 2018

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.

17 May 2018

Researchers discover mutation that can protect against Alzheimer's disease in mice

Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific mutation can reduce the characteristic accumulation of the amyloid-beta peptide that occurs.

16 May 2018

Blueprint of human heart chambers exists in zebrafish, study reports

Scientists have shown for the first time that the blueprint for the four chambers of the human heart exists in the humble zebrafish, a study in eLife reports.

16 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Mutation News and Research

Are you and your primary care doc ready to talk about your DNA?

Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

HCM mutation prevents the heart from increasing pumping force, study shows

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Gene therapy that reverses blindness in dogs could also help treat humans

Raising Awareness of Childhood Dementia

Ovarian cancer therapy may help treat patients with aggressive pancreatic cancer

Pancreatic cancer patients with BRCA1 or BRCA2 mutations fare better on platinum-based chemotherapy

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

Researchers discover mutation that can protect against Alzheimer's disease in mice

Blueprint of human heart chambers exists in zebrafish, study reports

Study uncovers promising new line of attack against aggressive prostate cancer

New drug reduces symptoms of Rett syndrome in preclinical models

Havard University grants license to Beam Therapeutics to develop new base editing technology

CRISPR-based treatment can restore retinal function in mice with eye disease

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Advances in Cell Lineage Analysis

New findings point to potential therapeutic avenues for leukemia

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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