Preclinical News and Research

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University of Salford introduces innovative pre-registration Master’s programme in podiatry

An innovative pre-registration Master’s programme in podiatry, which has been developed at the University of Salford has been launched, the first to be introduced in the UK.

29 Jan 2016

UCLA researchers find protein combination that could improve clinical bone restoration

A UCLA research team has found a combination of proteins that could significantly improve clinical bone restoration. The findings may be a big step toward developing effective therapeutic treatments for bone skeletal defects, bone loss and osteoporosis.

29 Jan 2016

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

A research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute has discovered a new class of small-molecule compounds that are good candidates for development of novel targeted therapies in the treatment of leukemia and lymphoma.

28 Jan 2016

Researchers identify cells that likely give rise to Group 4 medulloblastoma

Researchers have identified the cells that likely give rise to the brain tumor subtype Group 4 medulloblastoma. The finding removes a barrier to developing more effective targeted therapies against the brain tumor's most common subtype.

28 Jan 2016

Biomedical innovation in the UK: an interview with Zahid Latif

The biomedical research base is one of the UK's strengths; over 1500 companies in the Pharmaceuticals and biotechnology area are established in the UK employing over 70,000.

22 Jan 2016

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

A University of Colorado Cancer Center study being presented Saturday at the 2016 Genitourinary Cancers Symposium shows genetic differences between colorectal cancer (CRC) in young and old patients, possibly pointing toward different treatments and strategies in combating the young form of the disease.

22 Jan 2016

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

The immunotherapy platform at The University of Texas MD Anderson Cancer Center and the global biopharmaceutical company AbbVie will join forces to find new ways to unleash the immune system's potential to fight cancer.

21 Jan 2016

Philogen launches Phase III pivotal trial in patients with Stage IIIB/C melanoma

Philogen S.p.A. today announced the launch of a pivotal trial in patients with Stage IIIB/C melanoma, following promising results obtained in a Phase II study with an innovative immunotherapeutic approach.

21 Jan 2016

Technology leader award given to Leica Microsystems

Wetzlar, Germany. The research and consulting company Frost & Sullivan has recognized Leica Microsystems’ newly acquired Optical Coherence Tomography (OCT) company Bioptigen of Morrisville, North Carolina, USA, as a technology leader and pioneer of the North American ophthalmic imaging industry.

From Leica Microsystems GmbH 21 Jan 2016

UM SOM study leads to FDA approval of Neulasta drug for treatment of radiation injury

As a result of research performed by scientists at the University of Maryland School of Medicine, the U.S. Food and Drug Administration has approved the use of a drug to treat the deleterious effects of radiation exposure following a nuclear incident. The drug, Neulasta, is one of a very small number that have been approved for the treatment of acute radiation injury.

21 Jan 2016

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

In results published on October 19, 2015 in the Journal of Lipid Research, a team of translational scientists at the Medical University of South Carolina report a new reason why non-alcoholic steatohepatitis (NASH) worsens in people who are obese.

20 Jan 2016

Diabetes drug fails to show any benefit against pancreatic cancer

A diabetes drug that showed promise in previous studies as an anti-cancer treatment failed to show any benefit in a UNC Lineberger Comprehensive Cancer Center-led study that used pancreatic cancer tissue samples to test sensitivity to the drug.

20 Jan 2016

Four USF professors selected as AIMBE College of Fellows

Four University of South Florida professors have been elected to the 2016 College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE): Cesario Borlongan and Shyam Mohapatra from the USF Morsani College of Medicine, USF Health; and Robert Frisina, Jr., and Sudeep Sarkar from the USF College of Engineering.

20 Jan 2016

Hhex protein could be key target for new therapies to cure leukaemia

Melbourne researchers have showed that they can stop leukaemia in its tracks by targeting a protein that puts the handbrake on cancer cell growth.

20 Jan 2016

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the prevention and treatment of infectious diseases and the treatment of cancer, announced today the initiation of a Phase 1 clinical study of Profectus' VesiculoVax-vectored Ebola virus vaccine.

19 Jan 2016

Needle-free administration of anesthetic in the mouth could save costs, improve patient compliance

If you're scared of the dentist's needles you're not alone - but new research means you might not have to put off that appointment again. A study published in Colloids and Surfaces B: Biointerfaces reveals how the dentist could give you anesthetic using a tiny electric current instead of a needle.

19 Jan 2016

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

The joint venture between Biogen and Samsung BioLogics, Samsung Bioepis, has been granted European Commission (EC) approval for BENEPALI , an etanercept biosimilar referencing Enbrel.

19 Jan 2016

TSRI researchers develop new technique for modifying complex drug molecules

Chemists at The Scripps Research Institute have developed a versatile new technique for making modifications—especially one type of extremely difficult, but much-sought-after modification—to complex drug molecules.

18 Jan 2016

PK molecule could be a target for vascular complications linked to type 1 diabetes

In an article published ahead of print on November 24, 2015 in the journal Diabetes (available at http://dx.doi.org/10.2337/db15-0930), researchers from the Medical University of South Carolina, the American University of Beirut, and Case Western Reserve University report that a molecule called pre-kallikrein (PK) could be a target for the vascular complications associated with type 1 diabetes.

18 Jan 2016

Novel drug shows promise against metastatic breast cancer in mouse models

A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive to static, and no longer shedding cells that can colonize distant organs of the body.

12 Jan 2016

Preclinical News and Research

University of Salford introduces innovative pre-registration Master’s programme in podiatry

UCLA researchers find protein combination that could improve clinical bone restoration

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

Researchers identify cells that likely give rise to Group 4 medulloblastoma

Biomedical innovation in the UK: an interview with Zahid Latif

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

Philogen launches Phase III pivotal trial in patients with Stage IIIB/C melanoma

Technology leader award given to Leica Microsystems

UM SOM study leads to FDA approval of Neulasta drug for treatment of radiation injury

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

Diabetes drug fails to show any benefit against pancreatic cancer

Four USF professors selected as AIMBE College of Fellows

Hhex protein could be key target for new therapies to cure leukaemia

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Needle-free administration of anesthetic in the mouth could save costs, improve patient compliance

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

TSRI researchers develop new technique for modifying complex drug molecules

PK molecule could be a target for vascular complications linked to type 1 diabetes

Novel drug shows promise against metastatic breast cancer in mouse models

Event guide: 4th LNP Formulation & Process Development Summit eBook

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