Genomic News and Research

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Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Bacteria share genes with one another, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling - independent of their microbial hosts - from one part of the body to another, researchers report in the journal Scientific Reports.

11 Apr 2019

Scientists develop new approach to unravel toxic effects of multiple stressors

Genomic markers are the key in a new approach for assessing the toxic effects arising from exposure to multiple stressors.

11 Apr 2019

Scientists develop technique to clear abnormal tau protein from human neurons

Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders.

10 Apr 2019

New bioinformatics method helps scientists to understand differences in gene regulation in cells

A Belgian team of computational biologists led by Stein Aerts has developed a new bioinformatics method called cisTopic.

10 Apr 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019

'Battle royale' of oral pathogen helps explain how dangerous bacteria persist in hospital environment

Hundreds of different bacterial species are living inside your mouth. Some are highly abundant, while others are scarce. A few of these oral bacteria are known pathogens. Others are benign, or even beneficial.

9 Apr 2019

MGH researchers provide insight into use of critical care resources

A study by Massachusetts General Hospital investigators has found wide variation in the use of different hospital units - intensive care or general medical units - to deliver a type of advanced respiratory support called non-invasive ventilation.

8 Apr 2019

Digital Integration in Laboratory Practice Highlighted in LABVOLUTION 2019

LABVOLUTION is a product of BIOTECHNICA and saw its debut in 2015. Now, gearing up to launch its 2019 show, LABVOLUTION is Europe’s flagship lab tech trade event.

8 Apr 2019

Study uncovers genetic causes of poor sleep

The international collaboration, led by the University of Exeter and published in Nature Communications, has found 47 links between our genetic code and the quality, quantity and timing of how we sleep. They include ten new genetic links with sleep duration and 26 with sleep quality.

5 Apr 2019

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

The Institute for Genome Sciences at the University of Maryland School of Medicine was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases to fund the IGS Genome Center for Infectious Diseases for another five years.

5 Apr 2019

Study identifies possible way to predict which melanomas are hot and cold

Melanomas tend to be "hot" or "cold" - if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, and patients with cold tumors tend to show little benefit from immunotherapies.

4 Apr 2019

Study reveals new insights into genetic drivers of heavy drinking and alcohol use disorder

A large genomic study of nearly 275,000 people led by Penn Medicine researchers revealed new insights into genetic drivers of heavy drinking and alcohol use disorder, the uncontrollable pattern of alcohol use commonly referred to as alcoholism.

2 Apr 2019

Research identifies genomic risk factor associated with stroke in childhood cancer survivors

Research at St. Jude Children's Research Hospital has identified a genomic risk factor associated with stroke in childhood cancer survivors. The findings were announced today at a press conference as part of the American Association for Cancer Research annual meeting in Atlanta.

2 Apr 2019

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

Novel EU-funded project in the field of genomics

The European Advanced infraStructure for Innovative Genomics (EASI-Genomics), a project funded under the European Union's research and innovation programme Horizon 2020, will provide researchers free-of-charge access to cutting-edge European genomics facilities.

30 Mar 2019

Study highlights need to diversify population-level genetic data for better disease prediction

Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis tool holds promise for physicians, who may be able to intervene earlier to help prevent common disease for at-risk individuals.

30 Mar 2019

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

While non-small cell lung cancer is the more common form of lung cancer and attracts the lion's share of the research funding, recent developments in small cell lung cancer may be shifting that slightly.

29 Mar 2019

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

The Mount Sinai Health System and the Hasso Plattner Institute today announced an affiliation that brings together industry leaders with combined expertise in health care delivery, health sciences, biomedical and digital engineering, machine learning and artificial intelligence to rapidly develop digital health products with real-time predictive and preventive capabilities that empower patients and health care providers, and improve health and health outcomes.

29 Mar 2019

Genomic News and Research

Study describes vulnerability shared by large subset of cancer cell lines

Bacteria share genes with one another, even across tissue boundaries

Scientists develop new approach to unravel toxic effects of multiple stressors

Scientists develop technique to clear abnormal tau protein from human neurons

New bioinformatics method helps scientists to understand differences in gene regulation in cells

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

'Battle royale' of oral pathogen helps explain how dangerous bacteria persist in hospital environment

MGH researchers provide insight into use of critical care resources

Digital Integration in Laboratory Practice Highlighted in LABVOLUTION 2019

Study uncovers genetic causes of poor sleep

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

Study identifies possible way to predict which melanomas are hot and cold

Study reveals new insights into genetic drivers of heavy drinking and alcohol use disorder

Research identifies genomic risk factor associated with stroke in childhood cancer survivors

Research reveals genomic basis of acute erythroid leukemia

Novel EU-funded project in the field of genomics

Study highlights need to diversify population-level genetic data for better disease prediction

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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