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Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinson's disease.

4 Jun 2020

Researchers decipher deadly bacterial infection in pigs

The Clostridium perfringens bacterium is part of the large Clostridium genus which can cause various fatal illnesses in animals and humans.

4 Jun 2020

Using advanced microscopy techniques to see single molecules of telomerase in living cells

Canadian scientists have achieved a first in the study of telomerase, an essential enzyme implicated in aging and cancer.

3 Jun 2020

Tumors cause disruption of the immune system throughout the body, study finds

Cancer treatment has advanced with the advent of immunotherapies that, in some cancers, can overcome tumors' ability to evade the immune system by suppressing local immune responses.

3 Jun 2020

Researchers deconstruct the mechanisms that control wound healing

ETH researchers have deconstructed the mechanisms that control wound healing and scar formation in more detail.

3 Jun 2020

New test identifies CAD-affected children who may benefit from uridine

Scientists at Sanford Burnham Prebys Medical Discovery Institute and the Centro de Biología Molecular Severo Ochoa in Spain have created a test that determines which children with CAD deficiency - a rare metabolic disease - are likely to benefit from receiving uridine, a nutritional supplement that has dramatically improved the lives of other children with the condition.

3 Jun 2020

Bacteria that live in soil and on people have extensive antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

Cone snail venom produces new type of insulin

Diabetes is a global health issue affecting millions. In 2014, there were 422 million diabetics, compared to 108 million in 1989. The condition can be treated with diet, physical activity, medicines like synthetic insulin injections, and regular screening.

3 Jun 2020

Rigidity of tissues drives immune system activity, UCLA study finds

A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.

2 Jun 2020

Breakthrough discovery could lead to treatment of Fragile X syndrome

Scientists at the Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, and Owerko Centre at UCalgary's Cumming School of Medicine have made a breakthrough discovery that could lead to treatment of Fragile X syndrome, the leading genetic cause of Autism Spectrum Disorder.

2 Jun 2020

Spleen plays a dual role in malaria vivax

Plasmodium vivax is the most widely distributed human malaria parasite, mostly outside sub-Saharan Africa, and responsible for millions of clinical cases yearly, including severe disease and death. The mechanisms by which P. vivax causes disease are not well understood.

2 Jun 2020

Crucial ingredient from University of Kansas included in authorized COVID-19 drug

When the Food and Drug Administration issued an emergency-use authorization for the investigational pharmaceutical remdesivir to treat COVID-19 on May 1, in part it was due to pioneering work performed by pharmaceutical chemists at the University of Kansas School of Pharmacy in 1990.

1 Jun 2020

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

A research group from the University of Texas in Austin described a high-yield production of a stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) that may accelerate the development of vaccines and diagnostic tests. This methodological 'tour de force' paper is currently available on the bioRxiv* preprint server.

1 Jun 2020

Cone snail insulin research could jumpstart the development of better diabetes treatments

Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails.

1 Jun 2020

Anesthetic drug Ketamine uses serotonin receptors to relieve depression

Ketamine is a drug used to induce general anesthesia. It has also been found to act rapidly to relieve depression that has failed to respond to two other rounds of medication. A new study published in the journal Translational Psychiatry in May 2020 reports the mechanism of action of the drug, which was hitherto unknown. This could help find new ways to treat this debilitating and sometimes fatal condition.

31 May 2020

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of patients with a specific subtype of advanced bowel cancer, when compared with chemotherapy.

30 May 2020

Molecule News and Research

Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

Researchers decipher deadly bacterial infection in pigs

Using advanced microscopy techniques to see single molecules of telomerase in living cells

Tumors cause disruption of the immune system throughout the body, study finds

Researchers deconstruct the mechanisms that control wound healing

New test identifies CAD-affected children who may benefit from uridine

Bacteria that live in soil and on people have extensive antibiotic-destroying genes

Cone snail venom produces new type of insulin

Rigidity of tissues drives immune system activity, UCLA study finds

Breakthrough discovery could lead to treatment of Fragile X syndrome

Spleen plays a dual role in malaria vivax

Crucial ingredient from University of Kansas included in authorized COVID-19 drug

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

Cone snail insulin research could jumpstart the development of better diabetes treatments

Anesthetic drug Ketamine uses serotonin receptors to relieve depression

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

UMSOM scientists develop experimental rapid diagnostic test for COVID-19

Using gene therapy to help the body to make its own cancer drugs

Scientist explore potential drugs to prevent cell resistance in different types of cancer

Researchers use new technique to develop experimental rapid COVID-19 test

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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