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Cordoning off of lipids of the liver helps manage insulin resistance in the body

A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in which an enzyme called histone deacetylase 3 (HDAC3) was deleted had massively fatty livers, but lower blood sugar, and were thus protected from glucose intolerance and insulin resistance, the hallmark of diabetes.

7 May 2012

Oral nutriceutical restores vision to otherwise hopeless patients facing permanent loss

There may be new found hope for patients whose vision is threatened when medicine injected directly into the eyes fails to cause abnormal blood vessels to recede. While injectable drugs called angiogenesis (an-gee-oh-jen-esis) inhibitors are considered a modern miracle and have become the standard of care for patients with the fast-progressive form of macular degeneration, they are not foolproof.

7 May 2012

Seattle Children's Hospital performs 100th heart transplant on 5-month-old baby

On Saturday, April 28, a 5-month-old baby received the 100th heart transplant performed at Seattle Children's Hospital, a significant milestone for him as well as the hospital's Heart Center and Heart Transplant Program teams.

7 May 2012

Accentia, Johns Hopkins co-host meeting with prospective clinical trial investigators at AAN meeting

Accentia Biopharmaceuticals, Inc. today announced that the Company and leading physicians from Johns Hopkins University co-hosted a meeting with prospective clinical trial investigators at the recent American Academy of Neurology (AAN) Annual Meeting in New Orleans.

7 May 2012

UAB experts suggest meal guidelines for summer

It's already May. The heat is rising in the South, and the rest of the country soon will follow. Of course this means swimsuit season, and a plan to arrive at a healthy weight will help you look good at the pool and make you healthier overall, say University of Alabama at Birmingham experts.

5 May 2012

Human stem cells effective in treating muscular dystrophy

Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that - for the first time - makes the production of human muscle cells from stem cells efficient and effective.

5 May 2012

Researchers identify new mechanism that causes choroidal neovascularization

Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. The discovery has led researchers to urge review of how millions of dollars are spent investigating the cause of a type of age-related macular degeneration called choroidal neovascularization.

5 May 2012

PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Lung cancer is the leading cause of cancer death throughout the world. Standard treatment methods do not usually result in long-term recovery. In addition to the proliferation of the tumour cells, the growth of blood vessels controls tumors development. The blood vessel growth is controlled by several signalling molecules. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Justus Liebig University Giessen have discovered a molecule that plays a key role in this process. They succeeded in reducing tumour growth in their experiments by blocking the phosphodiesterase PDE4.

5 May 2012

Sound Interventions completes ultrasound clinical trial on resistant hypertension

Sound Interventions, Inc. today announced the successful completion of the company's First-In-Human clinical trial (SOUND-ITV) to treat resistant hypertension.

5 May 2012

TCFC completes two in-utero fetal cardiac interventions to treat HLHS

The team at Texas Children's Fetal Center, a national leader for treating fetal anomalies, has successfully completed two in-utero fetal cardiac interventions to treat hypoplastic left heart syndrome (HLHS), a congenital heart defect that is one of the most complex heart defects to treat.

5 May 2012

LRI applauds ACR colleagues for new lupus nephritis guidelines

The Lupus Research Institute (LRI) applauds our colleagues at the American College of Rheumatology (ACR) for issuing new guidelines to help healthcare professionals screen, diagnose and treat lupus nephritis, a type of kidney disease associated with lupus. Available on the ACR website, the new guidelines are just published in the April 2012 issue of Arthritis Care & Research.

5 May 2012

Low levels of testosterone in men could increase risk of diabetes

Low levels of testosterone in men could increase their risk of developing diabetes, a study suggests.

5 May 2012

Andrew Technologies launches HydraSolve Lipoplasty System at ASAPS meeting

Andrew Technologies, LLC launched the HydraSolve Lipoplasty System today at the American Society of Aesthetic Plastic Surgery (ASAPS) in Vancouver, BC.

5 May 2012

Highlights: D.C. may have funds for illegal immigrant health care; Fla. passed up $200M because it comes from health law; Texas to build 2 new med schools

D.C. Council member David A. Catania has found an additional $20 million in the budget to continue offering free health insurance to 19,000 undocumented immigrants, reversing a proposal by Mayor Vincent C. Gray (D) that could have restricted them from receiving emergency care. Catania (I-At Large) … has made full funding of the Alliance Insurance program a chief priority as the council prepares for final budget deliberations.

5 May 2012

New research about why people forego colorectal cancer screening

New research about why people forego colorectal cancer (CRC) screening suggests that three fears play a significant role; fear of embarrassment, fear of getting AIDS and fear of pain may make some seniors skip the potentially lifesaving tests.

5 May 2012

Isis commences ISIS-APOCIIIRx Phase 2 study in hypertriglyceridemia

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 study evaluating ISIS-APOCIIIRx in patients with hypertriglyceridemia.

5 May 2012

Researchers develop new kind of hip implant

Hip replacement is one of the most frequent operations carried out in Germany. Each year, doctors implant some 200,000 artificial hip joints. Often the artificial hips need to be replaced just ten years later. In the future, a new implant currently being developed using high technology materials could help prevent premature revision surgeries.

5 May 2012

Guidelines on cardiovascular disease prevention in clinical practice launched at EuroPRevent2012

The latest cardiovascular disease (CVD) prevention guidelines have been overhauled to produce a user friendly document with concise messages that awards greater weight than ever before to evidence from clinical trials and observational population studies. The "European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (version 2012)" - were launched at the EuroPRevent2012 meeting in Dublin, Ireland.

4 May 2012

Improved lung-cancer screening by combining blood test with CT imaging

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

4 May 2012

Presence of fetal cells is a double-edged sword for women

For the first time, scientists have found what could be a causative link between the concentration of circulating Y-chromosome fetal cells in women who gave birth to children of either sex and their risk of later developing breast cancer and colon cancer.

4 May 2012