Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Fibroblast activation protein (FAP)-targeted radioligand therapy is safe and effective for treating patients with progressive metastatic tumors, specifically advanced sarcomas, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

10 Jun 2024

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

In a groundbreaking advance that could revolutionize bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

6 Jun 2024

AI-driven mammography cuts workload by 33%, boosts breast cancer detection

Implementing AI in mammography screening significantly reduces radiologists' workload and improves breast cancer detection rates, according to a study in Denmark and the Netherlands.

6 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

AI improves breast cancer screening performance and reduces false-positives

Using artificial intelligence (AI), breast radiologists in Denmark have improved breast cancer screening performance and reduced the rate of false-positive findings. Results of the study were published today in Radiology, a journal of the Radiological Society of North America (RSNA).

4 Jun 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms.

22 May 2024

Study reveals no survival benefit from systemic therapy in very advanced solid tumors

Patients with very advanced solid tumors saw no significant improvement in overall survival after receiving systemic therapy, according to a study published today in JAMA Oncology by researchers at The University of Texas MD Anderson Cancer Center and Yale Cancer Center.

17 May 2024

New study finds Sfrp1 as a potential therapeutic target in cancer treatment

Cancer is a leading cause of death globally. One of the primary reasons why cancer is such a deadly disease is the ability of cancer cells to become drug-resistant.

15 May 2024

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024

Exploring microbiome dynamics in esophageal cancer

Esophageal cancer (EC) has two primary subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC).

9 May 2024

Study uncovers sex-based disparities in liver transplant survival rates

Liver transplantation is a life-saving option for those with hepatocellular carcinoma (HCC), the most prevalent type of liver cancer.

9 May 2024

New PET imaging agent shows promise in visualizing lesions in clear cell renal cell cancer patients

A novel investigational PET imaging agent can rapidly and accurately visualize lesions in clear cell renal cell cancer (ccRCC) patients according to new research published in the May issue of The Journal of Nuclear Medicine.

7 May 2024

Researchers identify novel biomarkers in renal cell carcinomas

A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

6 May 2024

Study reveals global underassessment and undertreatment of chronic hepatitis B

New evidence reveals global underassessment and undertreatment of chronic hepatitis B (HBV), especially among women and Asian minorities in the West, a new study in the Journal of Hepatology, published by Elsevier, details.

2 May 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

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