Cellular Biology News and Research

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Leica Microsystems offers preview of light sheet module for confocal microscope at ASCB annual meeting

At the annual meeting of the American Society for Cell Biology (ASCB) in Philadelphia, PA, USA, from December 6 to 10, 2014, Leica Microsystems offers visitors a preview of its latest development: a light sheet module as an optional add-on to the Leica TCS SP8 confocal microscope for the observation of developing organisms in real time and 3D. The synergy of light sheet and confocal microscopy opens novel fields of application.

From Leica Microsystems GmbH 5 Dec 2014

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

One of the main obstacles to finding effective therapies for human diseases has been our limited understanding of disease pathogenesis: we lack detailed knowledge of the cellular and molecular mechanisms that lead to the development of disease.

30 Nov 2014

Eminent molecular cell biologist awarded GRC fellowship

The Gutenberg Research College of Johannes Gutenberg University Mainz has awarded the coveted GRC fellowship to Professor Krishnaraj Rajalingam. In the upcoming years, he will lead a research team at the Research Center for Immunotherapy at Mainz University.

26 Nov 2014

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Surprisingly, even with decades of cryopreservation research, little progress has been made in the way frozen biospecimens are thawed. It’s still very common for researchers and clinicians to thaw cells and other frozen biological samples in a variety of manual ways ...

25 Nov 2014

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research.

24 Nov 2014

Logos Biosystems enters agreement with Stanford University to License “Clarity™” Technology

Logos Biosystems, a leading developer of various cellular imaging instruments for life science research, announced that it has entered into an agreement with Stanford University in order to access to the intellectual properties for the Clarity™ technology.

From Logos Biosystems 19 Nov 2014

Microscope objectives for ultra-deep biological imaging introduced by Olympus

Two dedicated microscope objectives optimized for deep, high-resolution imaging of life science specimens up to 8mm beneath the surface have been introduced by Olympus.

From Evident Corporation - Life Sciences 13 Nov 2014

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

In 2D, neurons tend to form limited connectivity reflective of the 3D complexity in the brain and have more limited cultivation time before reduction in functions.

4 Nov 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's 67th Annual Scientific Meeting.

31 Oct 2014

Lucideon to run Biodensol together with the University of Lyon

Lucideon is pleased to announce that, together with the University of Lyon, it has been successful in its application to run ‘Biodensol’, a 7th framework European project to provide a network for initial training in the field of dentistry.

From Lucideon 23 Oct 2014

Discovery may provide new therapeutic avenue to target autophagy in tumors

No matter what type of chemotherapy you attack a tumor with, many cancer cells resort to the same survival tactic: They start eating themselves.

10 Oct 2014

Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

FEI (NASDAQ: FEIC) announced today its new Teneo VS™ scanning electron microscope (SEM), which offers a VolumeScope™ capability for life science applications. The Teneo platform tightly integrates FEI’s latest-generation SEM with VolumeScope, an in-chamber microtome and proprietary analytical software to provide fully-automated, large-volume reconstructions with dramatically improved z-axis resolution.

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Sep 2014

Protein p66ShcA shows promise as biomarker to identify breast cancers with poor prognoses

A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to research published ahead of print in the journal Molecular and Cellular Biology.

26 Aug 2014

Allen Institute for Brain Science welcomes visiting scientist engineer

The Allen Institute for Brain Science welcomes a visiting scientist from Harvard and a visiting engineer from Georgia Tech: Sharad Ramanathan, Ph.D.; and Craig Forest, Ph.D. Both Ramanathan and Forest will bring their distinct knowledge and backgrounds to the expanding scientific teams at the Allen Institute.

22 Aug 2014

Live cell imaging solution launched by QImaging

QImaging™ today launched a new, all-in-one camera package that supports demanding live cell fluorescence imaging requirements. The Live Cell Imaging Package provides researchers with the sensitivity of EMCCD and the versatility of sCMOS camera technologies by combining QImaging’s Rolera™ Thunder EMCCD and optiMOS™ sCMOScameras. Now, researchers can address their unique imaging needs for a broader, more diverse set of scientific applications.

21 Aug 2014

Study sheds light on genetic alterations that may contribute to luminal B breast cancer

Researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine have uncovered new information about the genetic alterations that may contribute to the development of a subtype breast cancer typically associated with more aggressive forms of the disease and higher recurrence rates.

7 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Study shows that mice can identify specific odors amid complex olfactory environments

For many animals, making sense of the clutter of sensory stimuli is often a matter or literal life or death. Exactly how animals separate objects of interest, such as food sources or the scent of predators, from background information, however, remains largely unknown.

4 Aug 2014

Chronic obstructive pulmonary disease flare-ups: an interview with Dr. MeiLan Han, University of Michigan and Scott Cerreta, Director of Education, COPD Foundation

During a flare-up, symptoms of a patient’s COPD worsen significantly, and breathing becomes more difficult. A persistent increase in shortness of breath, cough and sputum production are typical symptoms.

30 Jul 2014

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

A recent scientific discovery showed that mutations in prickle genes cause epilepsy, which in humans is a brain disorder characterized by repeated seizures over time. However, the mechanism responsible for generating prickle-associated seizures was unknown.

23 Jul 2014