Genetic Engineering News and Research

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Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

This study revealed that the CV3-13 antibody can mediate Fc effector functions against S protein-expressing cells.

13 Sep 2021

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

11 Sep 2021

Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Weill Cornell receives NIH support to advance TB research

Tuberculosis (TB) is one of the deadliest infectious diseases in history and one of the few that naturally infects only humans.

4 Sep 2021

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Sepsis is the leading cause of death in Brazil's intensive care units (ICUs). Among patients who progress to the severe form of the disease, 40% die, and the survivors often suffer from cardiovascular and neurological complications, as well as a significant decline in immunity lasting for years after they are discharged from hospital.

2 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

1 Sep 2021

Family of proteins could be effective in reducing damage from ischemic stroke

Boosting a family of naturally occurring proteins that dampens inflammation in the body has been shown to be effective in reducing damage from an ischemic stroke, according to preclinical researchers at The University of Texas Health Science Center at Houston.

1 Sep 2021

Researchers decipher genetic mechanisms governing the speed of protein synthesis

In all eukaryotic organisms, genetic material is stored in the cell nucleus in the form of DNA. In order to be used, this DNA is first transcribed into messenger RNA in the cell cytoplasm, then translated into protein with the help of ribosomes, small machines capable of decoding messenger RNA to synthesise the appropriate proteins.

31 Aug 2021

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques.

26 Aug 2021

New artificial blood vessel platform for predicting organ transplant rejection

Organ transplantation involves the transplantation of organs from donors as a means to treat disease or injury, but there is a shortage of organs available for donation compared to the demand for organ transplantation.

25 Aug 2021

Study provides new insight into the mosquito immune system and disease transmission

A new study that details mosquito immune cells could shed light on the insect immune system and how mosquitoes transmit parasites that cause malaria.

25 Aug 2021

Princeton researchers build world's smallest mechanically interlocked biological structure

Researchers at Princeton University have built the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids called peptides.

25 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

Genetic Engineering News and Research

Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Enzyme appears to be a major driver of dangerous pregnancy complication

Researchers find potential new target for treating systemic inflammation in obesity

Weill Cornell receives NIH support to advance TB research

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

Family of proteins could be effective in reducing damage from ischemic stroke

Researchers decipher genetic mechanisms governing the speed of protein synthesis

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

New artificial blood vessel platform for predicting organ transplant rejection

Study provides new insight into the mosquito immune system and disease transmission

Princeton researchers build world's smallest mechanically interlocked biological structure

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

Review may help clarify the origins of SARS-CoV-2

Fruit fly provides insight into controlling carbs and fat

Arteriolar niche used by breast cancer cells to prepare for metastasis

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Study illuminates the link between cholesterol and Alzheimer's-associated toxic protein clumps

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo