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Loss of tumor suppressor p53 reshapes Wnt signaling to drive mutant cell expansion

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations.

1 Oct 2026

New project explores mitochondrial evolution across diverse life forms

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

1 Oct 2026

Varying mutation rates in healthy organs explain cancer risk

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

1 Oct 2026

Scientists discover new cell type that may help regulate blood vessel growth in the heart

Researchers have discovered a new cell type that may help regulate blood vessel growth in the heart during development and in response to injury, according to a study from Weill Cornell Medicine.

1 Oct 2026

New fluorescent paper strips make vitamin B12 testing simpler

Measuring vitamin B12 in food usually means bringing the sample to the laboratory. A new fluorescent sensor could help move part of that process onto something much simpler: a paper strip or cotton swab.

1 Oct 2026

Common gene variant reduces effectiveness of pediatric asthma drug

Children with a variant in the SERPINE1 gene – which is found in 60% of the population – may be less responsive to mepolizumab, a drug used to treat asthma flares, according to a study published in the Journal of Allergy and Clinical Immunology.

1 Oct 2026

New trial tests if diet can reduce bipolar depression symptoms

A clinical trial is set to test whether diet could help reduce depressive symptoms in people with bipolar disorder, comparing a high fat, low carbohydrate diet with standard NHS healthy eating advice.

1 Oct 2026

New study highlights heavy chewing tobacco burden in South Asia

A new study from the Institute for Health Metrics and Evaluation (IHME) finds that chewing tobacco use contributed to an estimated 251,000 deaths globally in 2023, with health loss overwhelmingly concentrated in South Asia.

1 Oct 2026

Trevogrumab cuts semaglutide-induced lean mass loss by half, study shows

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and in press with The Lancet shows that using the trevogrumab to inhibit myostatin, a protein that negatively regulates muscle mass, can reduce lean mass loss during treatment with semaglutide by 50% compared with semaglutide and placebo.

1 Oct 2026

FAU study uses Raman spectroscopy and AI to detect skin cancer

Skin cancer is the most common cancer in the United States and among the most common worldwide. Nearly 1.5 million new cases were diagnosed globally in 2024, including nearly 340,000 melanomas.

1 Oct 2026

Do you really need to fast before a blood test? It depends on the test

The impact of fasting on blood test results is analyte-specific, with most routine tests showing minimal differences, suggesting a need for flexible guidelines.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Early-onset type 2 diabetes trial demonstrates significant 24-week fat loss

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Regional Health Americas journal shows that in people who have developed early onset type 2 diabetes (EOT2D) (aged under 45 years), around half these T2D cases can be reversed with a low-energy diet combined with a structured exercise program.

1 Oct 2026

New antibiotic combinations aim to prevent recurrent bacterial vaginosis

Researchers and clinicians from Monash University and Bayside Health's Melbourne Sexual Health Centre are trialing new combinations of antibiotics to treat persistent bacterial vaginosis (BV), following their landmark discovery that the condition is sexually transmissible.

30 Sep 2026

Menstrual tracking apps lack evidence of health and performance benefits

Digital menstrual tracking risks creating more harm than benefit and requires greater scrutiny, warn experts in The BMJ today.

30 Sep 2026

Insurance hurdles and costs hinder access to blood cancer drugs

Patients with blood cancers often face major insurance hurdles and significant out-of-pocket costs when trying to access specialty oral anticancer medications, according to a new nationwide study led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

30 Sep 2026

Novel 'speech clock' can estimate a person's chronological age

A large study shows that machine-learning clocks based on speech can estimate chronological age and may also offer a window into brain aging, biological aging, cognitive health, cumulative burden, and dementia.

30 Sep 2026

Wearable device can track changes in stroke-related arm movement impairment

A team led by University of Massachusetts Amherst researchers has developed a wearable wrist device powered by a machine-learning algorithm that can continually track changes in arm movement impairment caused by strokes.

30 Sep 2026

UC San Diego receives funding to establish the Polysubstance Addiction Research Center

Researchers from University of California San Diego have received a $12.6 million award from the National Institute on Drug Abuse (NIDA) to establish the Polysubstance Addiction Research Center (PARC), a multidisciplinary center designed to uncover the biological factors that contribute to addiction across multiple substances.

30 Sep 2026

UVM receives historic contract to develop medical digital twins

What if doctors could test a customized treatment on a virtual version of a critically ill patient before administering it in real life? That's the promise of medical "digital twins."

30 Sep 2026