Metabolites News and Research

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Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Study shows how alcohol combined with burn trauma throws the intestinal microbiome into chaos

What happens in your gut after a night of heavy drinking and a severe burn injury? According to a new study, it might involve more than just pain and discomfort.

22 Apr 2025

GOT2 as a metabolic and immunologic target in pancreatic cancer

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and treatment-resistant malignancies.

20 Apr 2025

What sauerkraut can do for your gut

Fermented cabbage metabolites play a crucial role in maintaining gut barrier function, suggesting potential health benefits for inflammatory disorders.

16 Apr 2025

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.

16 Apr 2025

Peanuts pack a punch for youth: study finds cellular benefits

Daily consumption of skin-roasted peanuts for six months led to a modest but significant increase in telomere length among young, healthy adults, while peanut butter did not show this effect.

15 Apr 2025

Multi-omics analysis uncovers molecular drivers of non-viral liver cancer development

Researchers discover that inflammation and aging contribute to non-viral liver cancer development. Green tea's role in reversing some of the pathway dysregulation that may contribute to the cancer development and other therapies explored.

15 Apr 2025

Fermented cabbage could help protect the gut, study suggests

Is sauerkraut more than just a tangy topping? A new University of California, Davis, study published in Applied and Environmental Microbiology suggests that the fermented cabbage could help protect your gut, which is an essential part of overall health, supporting digestion and protecting against illness.

15 Apr 2025

Gut imbalances in autism linked to brain and behavior changes

A new USC study suggests that gut imbalances in children with autism may create an imbalance of metabolites in the digestive system - ultimately disrupting neurotransmitter production and influencing behavioral symptoms.

14 Apr 2025

Can gut microbes help prevent Alzheimer’s?

A comprehensive review explores how gut microbiota diversity and fitness influence Alzheimer’s disease (AD) risk through neuroinflammation, amyloid and tau pathology, and blood-brain barrier dysfunction. It highlights the therapeutic potential of probiotics, dietary interventions, and omics technologies in restoring microbial balance and preventing neurodegeneration.

13 Apr 2025

Fecal microbiota transplantation emerges as a promising approach to H. pylori eradication

FMT is a novel therapeutic approach that involves transferring microbiota from a healthy donor to a patient's gastrointestinal tract.

10 Apr 2025

Can psychedelics break compulsive eating habits in obesity?

A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.

10 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

High fiber diet helps protect against dangerous gut infections

A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria.

9 Apr 2025

Laser-based infrared molecular fingerprinting detects common cancers

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies.

9 Apr 2025

What happens if you significantly increase dietary folic acid intake?

Increased dietary folic acid intake may lead to adverse health effects, including inflammation and neurotoxicity, highlighting the need for optimal levels.

9 Apr 2025

Wiley releases updated Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library of Drugs, Poisons and Their Metabolites database

Wiley, one of the world's largest publishers and a global leader in research and learning, today announced the much-anticipated release of the second edition of Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library of Drugs, Poisons, and Their Metabolites.

From John Wiley and Sons - Scientific Publishers 8 Apr 2025

Metabolites News and Research

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

Study shows how alcohol combined with burn trauma throws the intestinal microbiome into chaos

GOT2 as a metabolic and immunologic target in pancreatic cancer

What sauerkraut can do for your gut

Gut bacteria turn bile acids into allies against cancer

Peanuts pack a punch for youth: study finds cellular benefits

Multi-omics analysis uncovers molecular drivers of non-viral liver cancer development

Fermented cabbage could help protect the gut, study suggests

Gut imbalances in autism linked to brain and behavior changes

Can gut microbes help prevent Alzheimer’s?

Fecal microbiota transplantation emerges as a promising approach to H. pylori eradication

Can psychedelics break compulsive eating habits in obesity?

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

High fiber diet helps protect against dangerous gut infections

Laser-based infrared molecular fingerprinting detects common cancers

What happens if you significantly increase dietary folic acid intake?

Wiley releases updated Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library of Drugs, Poisons and Their Metabolites database

Gut bacteria and blood metabolites directly affect children’s height, study finds

How your dairy choices could impact your risk of type 2 diabetes, new study shows

Gut microbiome interventions could stop type 1 diabetes in its tracks

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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