Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Combined clinical and genomic data better predicts COVID-19 severity

The current COVID-19 outbreak is one of the worst pandemics in history and has claimed millions of lives across the globe, overwhelmed healthcare systems, and created unprecedented socio-economic ramifications.

28 Mar 2021

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

In a recent article currently available on the bioRxiv* preprint server, researchers from Belgium and the U.S. demonstrated a robust replication model for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates in primary human epithelial cells at the air-liquid interface and appraised the antiviral effect of selected viral replication inhibitors.

28 Mar 2021

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

In a paper recently uploaded to the preprint server medRxiv*, clinical and demographic data from across the UK is compared to viral genome sequence data, identifying trends amongst the population affected, and across SARS-CoV-2 strains.

26 Mar 2021

The pressure is on to diagnose and treat chronic kidney disease

In this interview, Helen Yeh, the Vice President, Biopharmaceuticals Medical, Cardiovascular, Renal and Metablosim at AstraZeneca , talks News-Medical to about chronic kidney diseas (CKD).

From AstraZeneca 26 Mar 2021

New study may shed light on inflammatory bowel disease

Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

26 Mar 2021

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Altered cellular energetics, a hallmark of cancers, has been associated with obesity. However, links between systemic energy regulation and aberrant cancer cell metabolism have been lacking.

25 Mar 2021

Study examines the health effects of diet and resistance training in middle-aged adults

A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training.

25 Mar 2021

ColoradoSPH wins NIH grant to study how air pollutants impact kidney health of sugarcane workers

Three groups from the Colorado School of Public Health have been awarded a $3 million 5-year grant from the National Institutes of Health to study the effects of air pollution and climate on the kidney health of sugarcane workers in Guatemala.

25 Mar 2021

Fluoxetine (Prozac) performs strongly in vitro against SARS-CoV-2 (including mutants)

Researchers from Finland, to expand on these studies, tested some of these drugs against the new SARS-CoV-2 variants. The study is published on the preprint server bioRxiv.

24 Mar 2021

Increased replicative fitness of SARS-CoV-2 UK strain in human bronchial cells

A recent study from France showed that the UK variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – also known as B.1.1.7 variant – can replicate much more efficiently in a reconstituted human bronchial epithelium, which may explain why it spreads so rapidly in the human population. The study is currently freely available on the bioRxiv preprint server.

24 Mar 2021

Dandelion extract inhibits SARS-CoV-2 in vitro

An exciting new study describes a specific inhibitor of the SARS-CoV-2 found in an extract of the common dandelion that could provide a new and fruitful avenue of drug research.

23 Mar 2021

New review of post-acute COVID-19

The first year of the COVID-19 pandemic has taken the lives of millions of people around the world but has also left hundreds with lingering symptoms or completely new symptoms weeks after recovery.

23 Mar 2021

Study identifies metabolic processes associated with multiple, unrelated diseases

Many older, but also increasingly younger, people suffer from several diseases at the same time. Scientists at the Berlin Institute of Health at Charité – Universitätsmedizin Berlin, together with colleagues from Munich and the United Kingdom, have now identified common risk factors that predispose to multiple even seemingly unrelated diseases.

22 Mar 2021

AI-based system for real-time prediction of complications in intensive care units

Life-threatening situations occur time and again in an intensive care unit. To make sure that doctors can intervene in time, a team at the German Heart Center Berlin has developed AI-based software that regularly evaluates all monitoring data and alerts staff before a critical situation is reached.

22 Mar 2021

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

"The AMNOG procedure has passed its first practical test. It is practicable and can also be implemented in detail", emphasized IQWiG's Director Jürgen Windeler in October 2011, when the Institute had published its first early benefit assessment within the framework of the AM-NOG procedure (AMNOG = Act on the Reform of the Market for Medicinal Products).

22 Mar 2021

Study reveals worsening health profiles in Gen X and Gen Y

Recent generations show a worrying decline in health compared to their parents and grandparents when they were the same age, a new national study reveals.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

A new study examines data from Israel's vaccination campaign to assess the efficacy of the Pfizer-BioNTech mRNA vaccine across different demographics.

19 Mar 2021

Molecule produced by the immune system can reduce potency of antibiotics

Research from the University of Kent's School of Biosciences has revealed that a molecule produced by the human immune system can severely diminish the potency of certain antibiotics.

18 Mar 2021

New AI-based decision support system can help prevent anemia in hemodialysis patients

Anemia, a condition characterized by the lack of healthy red blood cells in the body, is common in patients with chronic kidney disease who need to undergo routine hemodialysis (a process that helps to "clean" the blood when the kidneys don't function well).

18 Mar 2021

Nephrology News and Research

Further Reading

Combined clinical and genomic data better predicts COVID-19 severity

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

Demographic and clinical comparison of the first and second COVID-19 waves in London, UK

The pressure is on to diagnose and treat chronic kidney disease

New study may shed light on inflammatory bowel disease

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Study examines the health effects of diet and resistance training in middle-aged adults

ColoradoSPH wins NIH grant to study how air pollutants impact kidney health of sugarcane workers

Fluoxetine (Prozac) performs strongly in vitro against SARS-CoV-2 (including mutants)

Increased replicative fitness of SARS-CoV-2 UK strain in human bronchial cells

Dandelion extract inhibits SARS-CoV-2 in vitro

New review of post-acute COVID-19

Study identifies metabolic processes associated with multiple, unrelated diseases

AI-based system for real-time prediction of complications in intensive care units

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

Study reveals worsening health profiles in Gen X and Gen Y

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

Molecule produced by the immune system can reduce potency of antibiotics

New AI-based decision support system can help prevent anemia in hemodialysis patients

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