Progenitor Cells News and Research

RSS

Low oxygen levels harm specific cells in the developing brain

Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear.

6 May 2019

Integrator complex proteins are crucial for healthy brain development in fruit flies, study finds

A study by Duke-NUS Medical School has found that members of the multiprotein 'Integrator complex', known for its role in gene regulation, are crucial for healthy brain development in fruit flies.

24 Apr 2019

Neuronal transport factor detects its target transcripts in more complex manner than previously thought

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought.

16 Apr 2019

Rare gut condition is more predictable from individual's genetic makeup, study finds

Hirschsprung disease - a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool - is more predictable from an individual's genetic makeup than previously envisioned.

11 Apr 2019

Researchers map genetic mutation behind incurable disease

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis.

10 Apr 2019

Transplantation of bone marrow-derived EPCs slows ALS disease progression

Transplantation of human bone marrow-derived endothelial progenitor cells into mice mimicking symptoms of amyotrophic lateral sclerosis (ALS) helped mor, University of South Florida researchers report.

3 Apr 2019

Researchers discover 'taste bud cells' in mice lungs after severe bout of flu

Most people who weather an infection with influenza fully recover after a week or two. But for some, a severe case of the flu can actually reshape the architecture of their lungs and forever compromise their respiratory function.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Scientists at Winship Cancer Institute of Emory University, Children's Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells' stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants.

25 Mar 2019

Study provides new insight into blood cell and immune cell production

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system.

22 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

New study contradicts previous views on skeletal growth mechanism

An international group of scientists under the supervision of a staff member of Sechenov University and Karolinska Institute found out that earlier views on the mechanisms that provide and regulate skeletal growth were wrong.

21 Mar 2019

Exosomes are key to SOS signal that the heart muscle sends out after heart attack, study reveals

Human cells shed exosomes. These tiny extracellular, membrane-bound vesicles can carry cargo for cell-to-cell communication, ferrying diverse loads of proteins, lipids or nucleic acids.

14 Mar 2019

New discovery of how organs form helps scientists to develop treatments for diabetes, cancer

In a new study, researchers at the University of Copenhagen show that the development of a certain type of immature stem cells - also known as progenitor cells - depends on the quantity of a special protein and interaction with other cells in the body.

14 Mar 2019

Study reveals how a regulatory molecule ensures appropriate supply of blood cells

The body needs to create a continuous supply of blood cells to enter circulation. Blood cells have a wide variety of functions ranging from supplying oxygen to tissues, fighting infections, and enabling the blood to clot upon injury.

13 Mar 2019

Nicotine could affect human embryonic development at the single-cell level

Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report February 28th in the journal Stem Cell Reports.

4 Mar 2019

Researchers discover new mechanism of bone growth

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden report that bone growth in mice takes place in accordance with the same principles as when new cells are constantly produced in blood, skin and other tissue.

27 Feb 2019

Researchers identify origin of immune cell that helps form healthy heart valves

UCLA researchers have identified for the first time the origin of an immune cell that plays a critical role in the formation of healthy heart valves. The findings could pave the way for new treatments for heart valve disorders, which can be caused by congenital defects, aging or disease.

22 Feb 2019

Johns Hopkins study describes cells that may help speed bone repair

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.

21 Feb 2019

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley as CEO.

20 Feb 2019