Protein C News and Research

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Novel computational platform can design synthetic protein receptors from scratch

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

28 Oct 2025

New drug can have a promising effect in cancer patients with active brain metastases

An international clinical study led by the Medical University of Vienna shows that the drug patritumab deruxtecan (HER3-DXd) can have a promising effect in patients with active brain metastases of various tumor types.

28 Oct 2025

Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders

Most people are born with two functioning copies of each gene-one inherited from each parent. In many cases, having just one working copy is enough for the body to function normally.

28 Oct 2025

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Maternal peanut and peanut butter consumption during pregnancy and breastfeeding shaped DNA methylation patterns in children, particularly in genes regulating neurodevelopment and inflammation. These findings suggest maternal diet can prime offspring epigenetic sensitivity to breastfeeding duration.

27 Oct 2025

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

27 Oct 2025

A new technique to tag senescent cells

When it comes to treating disease, one promising avenue is addressing the presence of senescent cells. These cells - also known as "zombie cells" - stop dividing but don't die off as cells typically do.

27 Oct 2025

TRF1 protein depletion linked to leaner mice and altered metabolism

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

27 Oct 2025

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain's sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need.

27 Oct 2025

Study reveals how eosinophils play a protective role against Candida infections

New research shows that eosinophils, immune cells usually linked to allergies, also play a protective role against Candida infections by using the CD48 receptor to recognize the fungus and release proteins that stop its growth.

27 Oct 2025

Unraveling the mystery of motor neuron degeneration in ALS

ALS, also known as Lou Gehrig's disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure even after more than a century and a half of research.

27 Oct 2025

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

27 Oct 2025

Are ultra-processed plant foods really worse than meat? Scientists weigh in

A new review challenges assumptions about ultra-processed foods, finding that plant-based versions, such as soymilk, meat analogs, and soft margarines, may lower cholesterol and disease risk compared with unprocessed animal foods when used as replacements.

26 Oct 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

24 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

Unlocking the secrets of vascular health through eye imaging

The tiny blood vessels in your eyes might hold the key to predicting a person's risk of developing heart disease and how fast they're biologically aging, according to researchers at McMaster University and Population Health Research Institute (PHRI) - a joint institute of Hamilton Health Sciences and McMaster.

24 Oct 2025

Unveiling the dual role of HIV integrase in viral replication

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

24 Oct 2025

Researchers map the complex sugar chains attached to rat serum proteins

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity.

24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

Men whose prostate cancer returns after surgery or radiation therapy may now benefit from a new drug combination shown in clinical trials to cut the risk of death by more than 40%.

23 Oct 2025

Dietary fat dictates seasonal eating rhythms, study finds

A new study from UC San Francisco shows that our natural eating patterns are more closely tied to seasonal rhythms than previously thought.

23 Oct 2025

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Protein C News and Research

Novel computational platform can design synthetic protein receptors from scratch

New drug can have a promising effect in cancer patients with active brain metastases

Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

New study reveals how the glucocorticoid receptor forms complex structures inside cells

A new technique to tag senescent cells

TRF1 protein depletion linked to leaner mice and altered metabolism

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

Study reveals how eosinophils play a protective role against Candida infections

Unraveling the mystery of motor neuron degeneration in ALS

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Are ultra-processed plant foods really worse than meat? Scientists weigh in

Mitochondria and lysosomes work together to control regulatory T cell activation

New insight into TRPM3 heat sensor reveals how the body detects temperature

Unlocking the secrets of vascular health through eye imaging

Unveiling the dual role of HIV integrase in viral replication

Researchers map the complex sugar chains attached to rat serum proteins

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

Dietary fat dictates seasonal eating rhythms, study finds

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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