Clinical Trial News and Research

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Eyeglasses for school students help improve academic achievement

Students who received eyeglasses through a school-based program scored higher on reading and math tests, Johns Hopkins researchers from the Wilmer Eye Institute and School of Education found in the largest clinical study of the impact of glasses on education ever conducted in the United States.

9 Sep 2021

Duke surgeons perform first 'donation after circulatory death' pediatric heart transplant

Surgeons at Duke University Hospital successfully performed a "donation after circulatory death" (DCD) heart transplant in a pediatric patient, demonstrating the potential expansion of eligible donor hearts for children with heart failure.

9 Sep 2021

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer's Disease Research Center (ADRC), part of a federally-funded national network of similar centers.

9 Sep 2021

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

The gut microbiome - the collection of bacteria, viruses, fungi, and other microorganisms that reside in our gastrointestinal tracts - can impact us in a variety of different ways, from our metabolism to our mood.

9 Sep 2021

Study: Nearly one in five patients with malignant pleural mesothelioma contracted COVID-19

Nearly one in five patients with malignant pleural mesothelioma (MPM) at a Barcelona hospital contracted COVID-19 during the pandemic.

8 Sep 2021

Study reveals better outcomes for patients treated on a mobile stroke unit

Ischemic stroke patients treated on a mobile stroke unit received anti-clot medication faster and ended up with less disability at 90 days, according to a study published today in the New England Journal of Medicine led by researchers at The University of Texas Health Science Center at Houston and Memorial Hermann-Texas Medical Center.

8 Sep 2021

Study pinpoints an entirely new approach for treatment of biliary atresia

Biliary atresia is the largest cause of end-stage liver fibrosis in children and the main reason children need liver transplants. Despite many years of worldwide research, scientists have not yet found a way to prevent the condition.

7 Sep 2021

EULAR's Consultation Service expanded to address a more extensive range of research needs

European Alliance of Associations for Rheumatology, EULAR More extensive research expert services are now available to European investigators who seek to address the needs of people with rheumatic and musculoskeletal diseases, including advice about patient involvement strategies, pragmatic study designs, qualitative research methods, and EU grant preparation.

7 Sep 2021

New Health Declaration published with commitments from all G20 countries

G20 Health Ministers have united to pledge global action to improve future health security, increase vaccine confidence and tackle antimicrobial resistance.

6 Sep 2021

Health Secretary urges G20 countries to recognize UK's COVID-19 vaccine clinical trial participants

The rights of vaccine clinical trial volunteers must be safeguarded to help protect everyone against future health crises, Health and Social Care Secretary Sajid Javid will tell G20 health leaders in Rome today (Sunday 5 September).

5 Sep 2021

Setting individual objectives for physical exercise and supporting their pursuit generates positive and long-lasting changes

The cardiovascular implications of physical exercise can be improved by helping individuals design and set out to accomplish key goals.

2 Sep 2021

Autistic children who have impaired executive functioning skills can face challenges at school

Researchers from Children's Hospital of Philadelphia (CHOP) have found that children on the autism spectrum who have impaired executive functioning skills, which help control thoughts, emotions, and actions, can face challenges at school that are different from the ones they face at home.

2 Sep 2021

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.

1 Sep 2021

Experts show waning effectiveness of COVID-19 vaccines over time

In a letter to The New England Journal of Medicine, publishing online September 1, 2021, an interdisciplinary team of physicians and public health experts at University of California San Diego measured the effectiveness of COVID-19 mRNA vaccines among health workers at UC San Diego Health, most notably during the emergence of the highly transmissible delta virus variant and coincident with the end of the state's mask mandate, allowing fully vaccinated persons to forgo face coverings in most places.

1 Sep 2021

Impact of neoadjuvant concurrent chemoradiation on exosomal markers expression in colorectal cancer

Oncotarget published "The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma" which reported that the impact of neoadjuvant concurrent chemoradiation on exosomal markers expression and their prognostic significance in patients with rectal adenocarcinoma are yet to be explored.

1 Sep 2021

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus.

1 Sep 2021

GripAble device helps stroke patients with arm weakness to do more physical training

Over five million people in the UK live with arm weakness, with stroke damage accounting for one million people of those people.

1 Sep 2021

UniSA researchers are putting cancer patients at the heart of clinical trials

From bench to bedside, the journey towards new cancer therapies is full of challenges. Clinical trials – where new treatments are tested on people – are vital, but with fewer than five per cent of cancer patients participating worldwide, it’s a long road to travel.

1 Sep 2021

Modified R-CODOX-M/IVAC regimen shows promise for treating sporadic Burkitt lymphoma

Burkitt lymphoma (BL) is a highly aggressive form of non-Hodgkin lymphoma (NHL) that comes in three different variants: endemic, immunodeficiency-associated, and sporadic. Of these variants, sporadic BL is most commonly found outside malaria-endemic countries and typically seen in young adults.

1 Sep 2021

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

After over a century of development, cancer immunotherapy (CIT) has risen to become a promising approach for treating cancer. Unlike conventional methods that try to kill cancer cells directly, CIT involves modifying or stimulating the immune system's natural ability to fight the disease. So far, various CIT treatments have shown remarkable results in terms of survival rates, and many new and combination strategies are currently under study.

1 Sep 2021

Clinical Trial News and Research

Eyeglasses for school students help improve academic achievement

Duke surgeons perform first 'donation after circulatory death' pediatric heart transplant

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

Study: Nearly one in five patients with malignant pleural mesothelioma contracted COVID-19

Study reveals better outcomes for patients treated on a mobile stroke unit

Study pinpoints an entirely new approach for treatment of biliary atresia

EULAR's Consultation Service expanded to address a more extensive range of research needs

New Health Declaration published with commitments from all G20 countries

Health Secretary urges G20 countries to recognize UK's COVID-19 vaccine clinical trial participants

Setting individual objectives for physical exercise and supporting their pursuit generates positive and long-lasting changes

Autistic children who have impaired executive functioning skills can face challenges at school

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Experts show waning effectiveness of COVID-19 vaccines over time

Impact of neoadjuvant concurrent chemoradiation on exosomal markers expression in colorectal cancer

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

GripAble device helps stroke patients with arm weakness to do more physical training

UniSA researchers are putting cancer patients at the heart of clinical trials

Modified R-CODOX-M/IVAC regimen shows promise for treating sporadic Burkitt lymphoma

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

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