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Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

Neutrophils may play a key role in COVID-19-related thrombosis

A team of researchers in Italy have published a study suggesting that rather than platelets, neutrophils could be playing the lead role in thrombotic complications associated with COVID-19.

9 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Why is COVID-19 more severe among adults than children?

Researchers in Switzerland and Australia have reviewed some of the mechanisms proposed regarding why coronavirus disease 2019 (COVID-19) is generally less severe among children than among adults.

8 Dec 2020

COVID-19 may be linked to acute appendicitis in children

Researchers at the University of Virginia have recently presented a case series pointing to a potential association between infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the development of acute appendicitis in children.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Transmission dynamics of SARS-CoV-2 in children: an Indian case study

Researchers have studied the primary contacts of COVID-19 positive children in India in May 2020 and found all children to be asymptomatic, and only four of the parents became positive. Although this suggests lower transmission from children, no recommendations can be made yet on school reopening.

8 Dec 2020

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

Scientists have revealed that certain bioactive compounds found in green, black, and oolong tea possess remarkable antiviral activities against SARS-CoV-2.

8 Dec 2020

Researchers identify new mechanism through which plants can regulate gene expression

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur.

8 Dec 2020

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

8 Dec 2020

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles.

8 Dec 2020

Enzyme News and Research

Tomatoes could become a new, natural source of Parkinson's disease drug

Neutrophils may play a key role in COVID-19-related thrombosis

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Why is COVID-19 more severe among adults than children?

COVID-19 may be linked to acute appendicitis in children

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Transmission dynamics of SARS-CoV-2 in children: an Indian case study

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

Researchers identify new mechanism through which plants can regulate gene expression

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Researchers use novel technology to prevent destruction of specific proteins inside cells

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

RUDN team suggests new tool to control inflammation in asthma patients with accompanying diseases

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

D614/G614 variants of SARS-CoV-2 affect neuronal transmission; G614 better at membrane fusion

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

Understanding the DNA Damage Response in Innate Immunity eBook

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