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Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

Mice study shows how to improve long-term effectiveness of TB vaccine

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

11 Mar 2022

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

People who gained immunity - either through vaccination or exposure - against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant.

11 Mar 2022

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Cancer patients who have compromised immune systems due to their disease or therapy remain at high risk for COVID-19 infection.

10 Mar 2022

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19.

10 Mar 2022

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

LMU scientists have investigated how most people's immune defenses are able to curb the coronavirus so effectively that pneumonia does not occur.

10 Mar 2022

Association of benzodiazepines with SARS-CoV-2 positivity and clinical outcomes in three patient groups

A new study has evaluated the association of BZD use with the clinical outcomes of SARS-CoV-2 positive patients.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

Mechanical stress of confined migration makes cancer cells more aggressive

Squeezing through tight spaces makes cancer cells more aggressive and helps them evade cell death, shows a study published today in eLife.

9 Mar 2022

Study suggests recent common cold may actually lead to worse COVID-19 disease

A new study published in the Journal of Infectious Diseases shines an unexpected light on the notion that pre-existing immunity to common cold coronaviruses can protect us from coronavirus disease 2019 (COVID-19) – and reveals that this may actually put certain individuals at risk of more severe clinical presentations.

8 Mar 2022

Researchers secure $12 million grant to develop improved therapies for hemophilia

An Indiana University School of Medicine researcher will lead a multi-institute effort toward improved therapies for hemophilia with help from a $12 million grant from the National Heart Lung and Blood Institute.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Study identifies new immune checkpoint that may be exploited for cancer treatment

A collaborative study led by the Monash Biomedicine Discovery Institute has discovered a new immune checkpoint that may be exploited for cancer therapy.

8 Mar 2022

Ketogenic diet leads to significant improvements in MS symptoms

Patients with relapsing-remitting multiple sclerosis (MS) who adopted a high-fat, low-carbohydrate ketogenic diet saw significant improvements in their MS – including reductions in neurologic disability, fatigue and depression and heightened overall quality of life, a new study finds.

8 Mar 2022

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A recent study assessed neutrophil extracellular trap formation and antiviral host response in high-risk COVID-19 patients.

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

A new study examined a unique case of extended viral shedding in an immunocompromised patient that produced a series of SARS-CoV-2 immune escape mutations over a seven-month period.

8 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Researchers investigate a predictive tool for the progression of rheumatoid arthritis

Predicting the future may be beyond our grasp, but what about predicting disease progression? Researchers in Japan have delved into the human genome to investigate a predictive tool for the progression of rheumatoid arthritis (RA), an inflammatory autoimmune disease showing progressive joint damage.

7 Mar 2022

Immune System News and Research

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Mice study shows how to improve long-term effectiveness of TB vaccine

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

Association of benzodiazepines with SARS-CoV-2 positivity and clinical outcomes in three patient groups

The trajectory of B-cell immunity six months after mRNA vaccination

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

Mechanical stress of confined migration makes cancer cells more aggressive

Study suggests recent common cold may actually lead to worse COVID-19 disease

Researchers secure $12 million grant to develop improved therapies for hemophilia

Study reveals new insights on how immune system cells respond to disease-causing pathogens

Study identifies new immune checkpoint that may be exploited for cancer treatment

Ketogenic diet leads to significant improvements in MS symptoms

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A promising approach for COVID-19 prophylaxis

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers investigate a predictive tool for the progression of rheumatoid arthritis

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