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New understanding of Leber congenital amaurosis

People suffering from a severe retinal disease will sooner or later lose their eyesight considerably or even become completely blind.

7 Aug 2007

Potential new biomarker for heart failure also strongly predicts risk of death

A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes.

7 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Overview of common hand conditions and treatments

When a wrist hurts, it could be carpal tunnel syndrome -- or something else. Over time, many conditions can affect crucial parts of the hands, causing everything from pain to the loss of normal function.

7 Aug 2007

Electrical device partly restores sense of balance in animals

Hearing and balance experts at Johns Hopkins report successful testing in animals of an electrical device that partly restores a damaged or impaired sense of balance.

7 Aug 2007

Backache sufferers who fear pain change movements

People who fear aggravating a backache will change the way they move to prevent more pain, a new study finds.

7 Aug 2007

18 to 25 percent of women suffer from migraines

For every man with a migraine, three women are struck by the severe headaches that often come with nausea, sensitivity to light and sound, and aura.

6 Aug 2007

LKB1 gene - new lung tumor-suppressor

Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice.

6 Aug 2007

Many heart attack patients still not getting emergency reperfusion

Far more of today's heart attack patients receive emergency angioplasty treatment or clot-busting drugs to re-open their clogged heart arteries than even a decade ago, a new study finds.

6 Aug 2007

Emergency angioplasty use rises, but some patients still miss out

Compared with their counterparts a decade ago, today's heart attack patients are receiving emergency angioplasty or clot-busting drugs to re-open clogged arteries at a far greater rate, but 10 percent of patients who could benefit from this life-saving treatment still do not receive it, according to a study published in The American Journal of Medicine by Yale and University of Michigan researchers.

6 Aug 2007

Rosacea the result of a trifecta of unfortunate factors

Rosacea is a common inflammatory skin disease that causes facial redness which affects as many as 14 million Americans.

6 Aug 2007

Zinc lozenges are not effective in treating colds

Despite 20 years of research, the benefits of zinc lozenges as a therapy for the common cold have not been proven.

3 Aug 2007

New device to treat chronic congestive heart failure

As part of a 40-site national trial, researchers at UT Southwestern Medical Center are studying a new medical device designed to treat patients with chronic congestive heart failure.

3 Aug 2007

Unlocking proteins from their cellular shell

Applying physical stress to cells, researchers at the University of Pennsylvania have demonstrated that everyday forces can alter the structure of proteins tucked within cells, unfold them and expose new targets in the fight against disease.

3 Aug 2007

Innovative gene therapy research for muscular dystrophy

A major grant of approximately $10 million from the National Institutes of Health will help investigators at Columbus Children's Research Institute (CCRI) at Columbus Children's Hospital learn more about strategies to treat muscular dystrophy, potentially leading to two new gene therapy approaches.

3 Aug 2007

Age is important in HRT use

Five years ago this summer the National Institutes of Health's stopped early a major portion of the Women's Health Initiative (WHI), a large and ambitious study to address the most common causes of death, disability and impaired quality of life in postmenopausal women.

3 Aug 2007

Gene fusion subtypes in prostate carcinoma have clinical implications

Building on an earlier study that used Oncomine to identify ETS-fusion proteins in prostate cancer (Science, Oct 28 2005), Tomlins et al. report the identification of four additional classes of ETS rearrangements in prostate cancer, each of which activates ETV1 by a different genetic mechanism (Nature, Aug 2 2007).

3 Aug 2007

Electricity - a new weapon for stalling the progression of cancer

Low-intensity electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest laboratory experiments and a small human trial, raising hopes that electric fields will become a new weapon for stalling the progression of cancer.

3 Aug 2007

Efalizumab effective in treatment of heavy psoriasis

A meta-analysis of four randomized Phase III placebo-controlled trials confirms that the injectable drug Efalizumab, a humanized therapeutic antibody designed to selectively and reversibly block the activation, reactivation and trafficking of T-cells that lead to the development of psoriasis, had an acceptable safety and efficacy profile in the treatment of psoriasis in heavy patients, researchers at Mount Sinai School of Medicine announced today.

3 Aug 2007

Discredited Korean embryonic stem cells' true origins revealed

A report from researchers at Children's Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells.

3 Aug 2007