Antibody News and Research

RSS

An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Three teams of Dartmouth researchers have been selected to receive the first awards from the Dartmouth Innovations Accelerator for Cancer.

17 Apr 2021

Researchers develop an effective strategy to fight against chronic myelomonocytic leukemia

Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University describe an ingenious strategy against chronic myelomonocytic leukemia (CMML) wherein an antibody-drug conjugate (ADC) comprising a cytotoxic drug payload linked to an antibody that selectively targets specific cell lines effectively blocks malignant cell proliferation at source.

16 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

Rapid mRNA vaccination effectively controls SARS-CoV-2 transmission in long-term care facilities

Vaccine rollouts all over the world are aimed at cutting short the coronavirus disease 2019 (COVID-19) pandemic by inducing antibody-mediated immunity to the virus. A new study, recently released on the medRxiv* preprint server, addresses the successful reduction in viral spread and case incidence among residents of long-term care facilities (LTCF).

16 Apr 2021

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

A new study, released on the medRxiv* preprint server, examines the presence of SARS-CoV-2-specific IgA in human milk and its association with the protection of breastfed infants against the disease.

16 Apr 2021

Recovered COVID-19 patients may need only a single vaccine dose, suggests study

People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose, according to new research from the Penn Institute of Immunology. The findings, published today in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response.

16 Apr 2021

Modeling study suggests how different SARS-CoV-2 mutations prevent antibody binding

This suggests a cocktail of antibodies will work better at neutralizing the virus than a single antibody alone. In a study published in the bioRxiv* preprint server, researchers report the structure of binding complexes of the different classes of antibodies to the spike RBD using computational modeling, which may also help explain how the virus generates escape mutations.

16 Apr 2021

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

By investigating antibody and T cell responses to a single dose of the Oxford–AstraZeneca COVID-19 vaccine, researchers from Sri Lanka and the United Kingdom have found that more than 90% of vaccinated individuals produced an adequate amount of antibodies after receiving only one dose of the vaccine – irrespective of their age and gender.

16 Apr 2021

Scientists illuminate how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively.

16 Apr 2021

Study: Previous COVID-19 infection does not completely protect against reinfection in young people

A past COVID-19 infection does not completely protect against reinfection in young people, according to an observational study of more than 3,000 healthy members of the US Marines Corps most of whom were aged 18-20 years, published in The Lancet Respiratory Medicine journal.

16 Apr 2021

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Researchers in the United States have demonstrated the efficacy of the vaccine INO-4800 against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers at Children's Hospital of Philadelphia have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A.

15 Apr 2021

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

A new study by researchers in Jerusalem indicates that while specific antibodies to the virus are present in both serum and ovarian follicles following infection or vaccination, there is no apparent adverse effect on follicular function as a result.

15 Apr 2021

High antibody and inflammatory mediator levels may predict severe COVID-19

A new study reports on biomarkers could help predict the progression of the viral illness to dangerous levels early enough to enable timely intervention.

15 Apr 2021

Population-based study shows the persistence of neutralizing antibodies against coronavirus

It is an open question to what extent protection against reinfection persists after overcoming a SARS-CoV-2 infection.

15 Apr 2021

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.

15 Apr 2021

Ebola virus's key protein uses molecular triggers in the human cell to change shape

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape - and biologists are taught that defined shape dictates the protein's destined function.

15 Apr 2021

Evidence of sustained immune responses weeks after Pfizer-BioNTech BNT162b2 vaccination

A new study published ahead of print in the Clinical Chemistry and Laboratory Medicine (CCLM) journal reports the production of a robust immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the Pfizer-BioNTech BNT162b2 vaccine. The increase in humoral immunity includes elevated Immunoglobulin G (IgG) and Immunoglobulin A (IgA) levels after the second mRNA dose.

14 Apr 2021

SARS-CoV-2 variants are widely spread across the Houston metropolitan area

In late 2020, several concerning SARS-CoV-2 variants emerged globally. They are believed to be more easily transmissible, and there is concern that some may reduce the effectiveness of antibody treatments and vaccines.

14 Apr 2021

Antibody News and Research

Further Reading

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Researchers develop an effective strategy to fight against chronic myelomonocytic leukemia

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Rapid mRNA vaccination effectively controls SARS-CoV-2 transmission in long-term care facilities

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

Recovered COVID-19 patients may need only a single vaccine dose, suggests study

Modeling study suggests how different SARS-CoV-2 mutations prevent antibody binding

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

Scientists illuminate how some antibodies can effectively disable ebolaviruses

Study: Previous COVID-19 infection does not completely protect against reinfection in young people

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

New machine learning method for designing more effective antibody drugs

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

High antibody and inflammatory mediator levels may predict severe COVID-19

Population-based study shows the persistence of neutralizing antibodies against coronavirus

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Ebola virus's key protein uses molecular triggers in the human cell to change shape

Evidence of sustained immune responses weeks after Pfizer-BioNTech BNT162b2 vaccination

SARS-CoV-2 variants are widely spread across the Houston metropolitan area

Industry Focus eBook - Cell biology (5th edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo