Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

EKF Molecular Diagnostics to exhibit PointMan DNA-enrichment technology at Tri-Con 2014

EKF, announces that its subsidiary company EKF Molecular Diagnostics is exhibiting its ground-breaking PointMan DNA-enrichment tech.

From EKF Diagnostics 11 Feb 2014

Scientists identify twenty proteins specifically secreted by primary effusion lymphoma cell lines

Primary effusion lymphoma (PEL) is a rare B-cell neoplasm distinguished by its tendency to spread along the thin serous membranes that line body cavities without infiltrating or destroying nearby tissue.

10 Feb 2014

Study: Ipilimumab with VEGF inhibitors may be potential option for melanoma patients

Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

5 Feb 2014

OGT awarded NHS tender to supply oligo-based arrays for cytogenetics

Oxford Gene Technology, provider of innovative genetics research and biomarker solutions to advance molecular medicine, has been awarded a significant tender by the UK National Health Service for the supply of oligo-based arrays for cytogenetics.

From Oxford Gene Technology 4 Feb 2014

Biotheranostics launches complete genomic tests for metastatic cancer patients

bioTheranostics, Inc., today introduced the bioT3 Metastatic Cancer Solution, a suite of genomic-based tests that provide personalized diagnostic information and therapeutic guidance for metastatic cancer patients across the continuum of care.

4 Feb 2014

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

Boehringer Ingelheim Pharmaceuticals, Inc. and Duke Clinical Research Institute have formed a unique collaborative relationship to uncover insights into idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease.

31 Jan 2014

AVEO Oncology, Astellas Pharma decide to discontinue BATON breast cancer clinical trial

AVEO Oncology today announced that AVEO and Astellas Pharma Inc. have jointly decided to discontinue the BATON (Biomarker Assessment of Tivozanib in ONcology) breast cancer clinical trial, a Phase 2 study in patients with locally recurrent or metastatic triple negative breast cancer (TNBC), due to insufficient enrollment.

30 Jan 2014

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Researchers at Erasmus University Medical Center Rotterdam, The Netherlands, led by Dr. Qiuwei Pan and Dr. Luc van der Laan, have discovered that spontaneous tumorigenic transformation of human mesenchymal stem/stromal cells (MSCs) can occur during cell culture expansion, although the frequency is relatively low and often only observed after extensive passage in culture.

30 Jan 2014

Hippocampal activity may reflect ‘core’ schizophrenia traits

Hippocampal function may be a useful biomarker for the response of patients with schizophrenia to medication, research suggests.

28 Jan 2014

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

BD, a leading global medical technology company, today announced the commercial availability of the CE-marked PAXgene Blood DNA Tube in Europe. The PAXgene Blood DNA Tube is the first blood collection tube designed specifically for in vitro diagnostic (IVD) genomic DNA testing. The product was developed by PreAnalytiX GmbH, a joint venture between BD and QIAGEN.

From BD (Becton, Dickinson and Company) 28 Jan 2014

New halal testing method for detecting pig and horse contamination of meat

The mislabeling of meat products sold for human consumption has serious implications from a safety and ethical perspective. With recent news stories of pork and horsemeat contamination in different parts of the world, a renewed need for specialized testing of the food supply has rapidly arisen.

28 Jan 2014

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Researchers at the Kennedy Krieger Institute recently announced study findings showing the successful development of a humanized preclinical model for facioscapulohumeral muscular dystrophy (FSHD), providing scientists with a much needed tool to accelerate novel therapeutic research and development.

28 Jan 2014

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

A biomarker widely used to diagnose brain injury has shown early promise for assessing the severity of heart inflammation, or myocarditis, find researchers at Columbia University's Mailman School of Public Health, Johns Hopkins, and the Mayo Clinic.

28 Jan 2014

Researchers discover simple blood test that can predict diabetes risk much earlier

An estimated 25.8 million Americans have diabetes. Another 79 million are thought to have "prediabetes," meaning they are at risk of developing type-2 diabetes.

28 Jan 2014

New biomarker for stress in wild animals facing global climate change

Chemical analyses by neuroscientist Jerrold Meyer and colleagues at the University of Massachusetts Amherst are helping to establish hair cortisol concentration (HCC) as an important new biomarker for stress in wild animals facing global climate change.

25 Jan 2014

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

Venaxis, Inc., an in vitro diagnostic company focused on obtaining FDA clearance and commercializing its CE Marked APPY1 Test, a rapid, multiple biomarker-based assay for identifying patients that are at low risk for appendicitis, today announced completion of patient enrollment in its pivotal clinical study of the APPY1 Test in the United States.

24 Jan 2014

Collaboration between NFL and GE seeks to improve safety of athletes, soldiers who sustain mild TBI

When the Broncos and the Seahawks meet on the gridiron for Superbowl XLVIII, player and team statistics - passer ratings, rushing yards, sacks and fumbles - will be tossed around like, well, a football.

24 Jan 2014

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Researchers at Penn Medicine have generated a brain development index from MRI scans that captures the complex patterns of maturation during normal brain development.

22 Jan 2014

Tumor profiling study of colorectal cancer to be presented at 2014 Gastrointestinal Cancers Symposium

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of personalized medicine, will present a large international tumor profiling study of colorectal cancer at the 2014 Gastrointestinal Cancers Symposium this week in San Francisco, Calif. With more than 7,000 patients comprehensively profiled by Caris Molecular Intelligence, this study represents the largest, multi-national analysis in a single laboratory setting of the main molecular anomalies in colorectal cancer.

18 Jan 2014

Biothera enhances innate immune responses to Imprime PGG drug candidate

Biothera has enhanced innate immune responses to its cancer immunotherapy drug candidate Imprime PGG in subjects regardless of biomarker status, demonstrating the opportunity to treat a larger patient population. The in vitro research will be presented today at the Cambridge Healthtech Institute's Antibody-Drug Conjugates/Engineering Targeted Therapeutics conference in Palm Springs, CA.

16 Jan 2014

Biomarker News and Research

Further Reading

EKF Molecular Diagnostics to exhibit PointMan DNA-enrichment technology at Tri-Con 2014

Scientists identify twenty proteins specifically secreted by primary effusion lymphoma cell lines

Study: Ipilimumab with VEGF inhibitors may be potential option for melanoma patients

OGT awarded NHS tender to supply oligo-based arrays for cytogenetics

Biotheranostics launches complete genomic tests for metastatic cancer patients

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

AVEO Oncology, Astellas Pharma decide to discontinue BATON breast cancer clinical trial

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Hippocampal activity may reflect ‘core’ schizophrenia traits

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

New halal testing method for detecting pig and horse contamination of meat

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

Researchers discover simple blood test that can predict diabetes risk much earlier

New biomarker for stress in wild animals facing global climate change

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

Collaboration between NFL and GE seeks to improve safety of athletes, soldiers who sustain mild TBI

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Tumor profiling study of colorectal cancer to be presented at 2014 Gastrointestinal Cancers Symposium

Biothera enhances innate immune responses to Imprime PGG drug candidate

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