Clinical Trial News and Research

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Hyfe’s smartphone cough-tracking app used in a groundbreaking epidemiological research

Hyfe, a cough monitoring smartphone app and digital diagnostics tool developed by an international team of scientists and public health professionals, recently announced that their technology is now being incorporated into groundbreaking research in Spain in partnership with the University of Navarra, and involving over 800 participants.

26 Aug 2021

BioPlx sets out to control and combat the rise of antibiotic-resistant superbugs

Antimicrobial Resistance is "one of the greatest threats to society, human and animal health, and economic prosperity." Those are the unequivocal words regarding the gravity of antimicrobial-resistant bacteria from the National Institute of Antimicrobial Resistance Research and Education.

26 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

Virtual reality can reduce pain and anxiety in children undergoing IV catheter placement

It isn't a matter of one needle puncture. Many children coming through the doors of Children's Hospital Los Angeles are seen for chronic conditions and often require frequent visits. Painful procedures - like a blood draw or catheter placement - can cause anxiety and fear in patients.

25 Aug 2021

Enzyme related to rattlesnake neurotoxin linked with COVID-19 infection severity

Study shows that an enzyme may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target.

25 Aug 2021

Combination of metformin and chemoradiation does not add survival benefit in patients with LA-NSCLC

A combination of metformin and chemoradiation in patients with locally advanced non-small cell lung cancer (LA-NSCLC) was not found to add survival benefit in the NRG Oncology clinical trial NRG-LU001. These results were recently published in JAMA Oncology.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Major UK study redefines care for critically ill children on ventilation

A major UK clinical trial led by Queen’s University Belfast has shown how a new approach to reduce the use of mechanical ventilation can greatly improve outcomes for critically ill infants and children.

24 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

A new clinical trial to determine whether a third dose of vaccine will improve the immune response for people who have weakened immune systems is launching in the UK.

24 Aug 2021

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

24 Aug 2021

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

23 Aug 2021

New AI blood test found to detect over 90% of lung cancers

A novel artificial intelligence blood testing technology developed by researchers at the Johns Hopkins Kimmel Cancer Center was found to detect over 90% of lung cancers in samples from nearly 800 individuals with and without cancer.

20 Aug 2021

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

Following on from a thorough review of the evidence carried out by the MHRA, and recommendation by the Commission on Human Medicines (CHM), the government's independent expert scientific advisory body, the MHRA has approved Ronapreve as the first monoclonal antibody combination product indicated for use in the prevention and treatment of acute COVID-19 infection for the UK.

20 Aug 2021

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

The Biden administration's plans to make covid-19 booster shots available next month has drawn a collective scream of protest from the scientific community.

20 Aug 2021

MD Anderson receives nearly $13 million from CPRIT to support research efforts

The University of Texas MD Anderson Cancer Center has been awarded $12.75 million from the Cancer Prevention and Research Institute of Texas to support basic, clinical, translational and prevention research efforts, including $3 million for a new project to build clinical trial network infrastructure across Texas.

19 Aug 2021

Early clinical trial data in for whole virus COVID-19 vaccine candidate

In a study uploaded to the preprint server medRxiv*, the efficacy of a whole virion Coronavirus vaccine was determined by giving the vaccine to healthy adult volunteers, which generated a robust immune response with evidence of T-cell activation.

19 Aug 2021

Phase I clinical study evaluates safety and pharmacokinetics of ExeVir's COVID-19 neutralizing antibody

ExeVir, which is developing single domain antibody therapies providing broad protection against viral infections, today announces that the first subjects have been dosed in a Phase I clinical study of XVR011, its llama-derived antibody for the treatment and prevention of COVID-19.

19 Aug 2021

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

All COVID-19 vaccines appear less effective when faced with variants such as Delta, according to a new medRxiv* study. However, the researchers suggest that booster shots may help improve immunity and protect against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

18 Aug 2021

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

A new phase I clinical study shows, for the first time, how treatment with a type of stem cell called mesenchymal stromal cells is able to regulate important factors driving inflammation in patients with chronic obstructive pulmonary disease (COPD) for a period for time.

18 Aug 2021

Clinical Trial News and Research

Hyfe’s smartphone cough-tracking app used in a groundbreaking epidemiological research

BioPlx sets out to control and combat the rise of antibiotic-resistant superbugs

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

Virtual reality can reduce pain and anxiety in children undergoing IV catheter placement

Enzyme related to rattlesnake neurotoxin linked with COVID-19 infection severity

Combination of metformin and chemoradiation does not add survival benefit in patients with LA-NSCLC

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Major UK study redefines care for critically ill children on ventilation

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

New AI blood test found to detect over 90% of lung cancers

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

MD Anderson receives nearly $13 million from CPRIT to support research efforts

Early clinical trial data in for whole virus COVID-19 vaccine candidate

Phase I clinical study evaluates safety and pharmacokinetics of ExeVir's COVID-19 neutralizing antibody

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

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