Transplant News and Research

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Majority of children can safely quit anti-rejection drugs after liver transplant from parents

Physicians at three transplant centers have found in a pilot study that a majority of children who receive liver tissue from a parent can eventually stop using immunosuppression (anti-rejection) medications safely. These drugs, which tamp down natural immune function, have been linked to a bevy of complications, including cancer, diabetes, hypertension and kidney failure.

1 Feb 2012

CPET measurement predicts mortality in patients following liver transplantation

Researchers from the U.K. determined that preoperative cardiopulmonary exercise testing (CPET) is a specific predictor of 90-day survival following liver transplantation.

1 Feb 2012

Cardiopulmonary exercise testing may predict post-liver transplantation survival

Researchers from the U.K. determined that preoperative cardiopulmonary exercise testing (CPET) is a specific predictor of 90-day survival following liver transplantation. Study results available in the February issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, shows that the CPET measurement—the anaerobic threshold or fitness level—significantly predicts mortality in patients post-transplantation.

31 Jan 2012

Non-smoking, non-drinking transplant patients more likely to develop head and neck cancer

Transplant patients who develop head and neck cancer are more likely to be non-smokers and non-drinkers, and less likely than their non-transplant counterparts to survive past one year of diagnosis, according to a new study from Henry Ford Hospital in Detroit.

30 Jan 2012

Rapid discontinuation of prednisone after kidney transplant can help prevent side effects

Rapid discontinuation of the immunosuppressive steroid prednisone after a kidney transplant can help prevent serious side effects, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

27 Jan 2012

New system safe, effective in delivering CsA to organ transplant patients

A new system for delivering a drug to organ transplant patients, which could avoid the risk of harmful side effects, is being developed by scientists at the University of Strathclyde in Glasgow.

27 Jan 2012

Study: Live liver donor transplantation safer than previously believed

People who donate a portion of their livers for transplant to a relative or friend whose liver is failing can generally expect to live long, healthy lives and recover safely from the donation surgery, Johns Hopkins researchers have found.

27 Jan 2012

Major surgery to donate a portion of liver does not interfere with long, healthy life

26 Jan 2012

BioTime obtains license from Wistar Institute for technology related to SP100 gene

BioTime, Inc. today announced that it has obtained an exclusive license from The Wistar Institute in Philadelphia, PA for technology related to a gene designated as SP100.

25 Jan 2012

Cholesterol receptor allows entry of HCV virus into human liver cells

A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine.

24 Jan 2012

Patient enrollment complete in Enlivex Phase I/II clinical trial for autoimmune diseases

Hadasit Bio-Holdings a publicly traded portfolio of biotech companies, all based on intellectual property developed and owned by Hadassah University Hospital, Israel's foremost medical research center, today announced that the recruitment of 13 patients for the Enlivex Phase I/II clinical trial has been completed.

23 Jan 2012

Awake ECMO may be an effective bridging strategy for lung transplantation candidates

Extracorporeal membrane oxygenation (ECMO) support in awake, non-intubated patients may be an effective strategy for bridging patients to lung transplantation, according to a new study from Germany.

21 Jan 2012

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided.

18 Jan 2012

Alpha-1-antitrypsin may reduce effects of GVHD

A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants.

18 Jan 2012

Ivera receives new FDA clearance for Curos disinfecting port protector

Ivera Medical Corporation today announced it has received a new FDA 510(k) clearance for its Curos disinfecting port protector which reflects the company's ongoing determination to continuously improve its products to better deliver solutions designed to reduce hospital-acquired catheter related bloodstream infections.

18 Jan 2012

Nurse donates kidney to patient

A nurse offered to donate her own kidney to a 23-year-old patient. Allison Batson spent two years on the transplant floor of Emory University Hospital before her encounter with Clay Taber, a recent Auburn University graduate who fell sick one day after his 22nd birthday. He was diagnosed with kidney failure. The Auburn University graduate was diagnosed with Goodpasture's syndrome, a rare autoimmune disease that can result in severe damage to the kidneys and lungs.

17 Jan 2012

New way to block HCV infection in the liver

Researchers at the University of British Columbia have found a new way to block infection from the hepatitis C virus (HCV) in the liver that could lead to new therapies for those affected by this and other infectious diseases.

17 Jan 2012

Man gets new windpipe with stem cell therapy

Christopher Lyles, 30, of Abingdon, Md, became the first American to undergo an experimental procedure, involving stem cells to treat his trachea cancer. A trachea or windpipe connects the nose and mouth to the lungs, serving a crucial function for life.

16 Jan 2012

Many seniors with kidney disease are good candidates for transplants

Thousands more American senior citizens with kidney disease are good candidates for transplants and could get them if physicians would get past outdated medical biases and put them on transplant waiting lists, according to a new study by Johns Hopkins researchers.

13 Jan 2012

New NIST clinical SRM can help in accurate CMV detection and treatment

A new clinical Standard Reference Material (SRM) from the National Institute of Standards and Technology (NIST) will help health care professionals more accurately diagnose and treat cytomegalovirus (CMV), a common pathogen that is particularly dangerous for infants and persons with weakened immune systems.

12 Jan 2012

Transplant News and Research

Majority of children can safely quit anti-rejection drugs after liver transplant from parents

CPET measurement predicts mortality in patients following liver transplantation

Cardiopulmonary exercise testing may predict post-liver transplantation survival

Non-smoking, non-drinking transplant patients more likely to develop head and neck cancer

Rapid discontinuation of prednisone after kidney transplant can help prevent side effects

New system safe, effective in delivering CsA to organ transplant patients

Study: Live liver donor transplantation safer than previously believed

Major surgery to donate a portion of liver does not interfere with long, healthy life

BioTime obtains license from Wistar Institute for technology related to SP100 gene

Cholesterol receptor allows entry of HCV virus into human liver cells

Patient enrollment complete in Enlivex Phase I/II clinical trial for autoimmune diseases

Awake ECMO may be an effective bridging strategy for lung transplantation candidates

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Alpha-1-antitrypsin may reduce effects of GVHD

Ivera receives new FDA clearance for Curos disinfecting port protector

Nurse donates kidney to patient

New way to block HCV infection in the liver

Man gets new windpipe with stem cell therapy

Many seniors with kidney disease are good candidates for transplants

New NIST clinical SRM can help in accurate CMV detection and treatment

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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