Addiction News and Research

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Exploiting cancer cell 'addiction' may lead to new therapies

A new study uncovers a gene expression signature that reliably identifies cancer cells whose survival is dependent on a common signaling pathway, even when the cells contain multiple other genetic abnormalities.

1 Jun 2009

Catalyst Pharmaceutical Partners announces top-line results of CPP-109 phase II trial for cocaine addiction

Catalyst Pharmaceutical Partners, Inc. has announced top-line results from its U.S. Phase II clinical trial to treat cocaine addiction.

31 May 2009

Impaired ability to monitor behavior, emotions may underlie vulnerability to drugs; suggests new targets for treatment

Parts of the brain involved in monitoring behaviors and emotions show different levels of activity in cocaine users relative to non-drug users, even when both groups perform equally well on a psychological test.

25 May 2009

Extreme caffeinated soft drink diet leaves woman with serious health issues

Reports in the media of a New Zealand woman's extreme Red Bull diet where her weight plummeted from 105kg to 60kg by drinking 10 to 14 cans of the 'energy' drink each day say she has been left with serious health issues.

24 May 2009

Double the number of Australians now being treated for heroin addiction

The latest report from the Australian Institute of Health and Welfare (AIHW) shows in the last decade the number of Australians being treated for heroin, or other opioid, addiction has almost doubled.

22 May 2009

Cancer drugs erlotinib and gefitinib might treat alcoholism

A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol.

22 May 2009

People with darker skin might be more susceptible to nicotine addiction

Blacks and others with darker skin might be at greater risk for tobacco addiction than whites and those with lighter skin because the greater the amount of melanin, the coloring pigment in skin, the more nicotine appears to be stored, according to preliminary findings published in the journal Pharmacology, Biochemistry and Behavior, the New York Times reports.

19 May 2009

A new path for cocaine addiction research

Cocaine is one of the oldest drugs known to humans, and its abuse has become widespread since the end of the 19th century. At the same time, we know rather little about its effects on the human brain or the mechanisms that lead to cocaine addiction.

19 May 2009

The impact of third hand smoke on risk for genetic mutations wins Addiction Science Award

A resourceful study into the effect of third hand smoke upon the risk for genetic mutations in fruit flies won the top Addiction Science Award at this year's Intel International Science and Engineering Fair (ISEF), the world's largest science competition for high school students.

18 May 2009

Common gene variation explains why some women may find it more difficult to quit smoking during pregnancy

Researchers from the Peninsula Medical School and the University of Bristol, using data from the Avon Longitudinal Study of Parents and Children and the Exeter Family Study of Childhood Health, have identified a common genetic variant that explains why some women may find it more difficult to quit smoking during pregnancy.

15 May 2009

Morphine patches create addiction

Morphine patches are supposed to reduce use of painkillers, and provide more control over their use in chronic pain conditions. But researchers at the Norwegian University of Science and Technology (NTNU) and St. Olavs Hospital in Trondheim have found otherwise.

15 May 2009

Research shows how cocaine regulates gene expression in a crucial reward region

The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction.

13 May 2009

Promising new targets for medications to treat cocaine addiction

Repeated use of addictive drugs such as cocaine causes long-lasting changes in parts of the brain involved in motivation and reward, among others, yet the precise mechanisms by which these changes are maintained are poorly understood.

13 May 2009

Discovery of pathway that reactivate myelin repair

UMDNJ researchers have identified a key pathway that could lead to new therapies to repair nerve cells' protective coating stripped away as a result of autoimmune diseases such as Multiple Sclerosis (MS). An article reporting their findings will appear in the May 13 online edition of the Journal of Neuroscience.

12 May 2009

Research suggests potential new treatment for anxiety disorders and depression

New research on a brain chemical involved in development sheds light on why some individuals may be predisposed to anxiety. It also strengthens understanding of cellular processes that may be common to anxiety and depression, and suggests how lifestyle changes may help overcome both

12 May 2009