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Scientists develop new way to deliver molecules that target specific genes within cells

A group of researchers from University of Toronto Engineering and SickKids Hospital have developed a new way to deliver molecules that target specific genes within cells.

4 May 2020

SARS-CoV-2 receptor ‘mimic' could prevent COVID-19

Researchers from Italy have developed an exciting new peptide drug that could potentially prevent the coronavirus from infecting people’s cells. The paper, published on the preprint server bioRxiv* in April 2020, describes a small molecule that can bind to and block the attachment site on the virus spike protein, preventing its entry into the host cell.

4 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

New findings on polymer structures could improve targeted medicine delivery

The new development, recently reported in the scientific journal Nature Communications, was led by Christopher Li, PhD, a professor in Drexel's College of Engineering whose research has centered around engineering polymer structures for special applications, in collaboration with Bin Zhao, PhD, a professor in the Chemistry Department at the University of Tennessee, Knoxville.

3 May 2020

Nanostimulators can amp up stem cells' regenerative powers for muscle repair

In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

3 May 2020

Study finds Lin28 as promising therapeutic target for central nervous system injuries

Like power lines in an electrical grid, long wiry projections that grow outward from neurons - structures known as axons - form interconnected communication networks that run from the brain to all parts of the body.

2 May 2020

Long-lasting, low toxicity antimicrobial peptide fights 'superbug' lung infections

Researchers considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria.

1 May 2020

Spike protein analysis from India's first SARS-CoV-2

A new study published on the preprint server bioRxiv analyzes viral spike protein sequences from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in West Bengal, India, comparing them with sequences from other Indian states and Wuhan, China.

30 Apr 2020

Scientists generate molecular models of compounds relevant for COVID-19

The discovery of suitable drugs that could help treat diseases is a long process. However, computer-aided drug design and simulation could speed up the process and also increase the possibilities say experts. This form of drug design and simulation could soon be the gold standard in drug development.

30 Apr 2020

Nanodevices could prevent plaque formation in the brain

Alzheimer's disease is the sixth leading cause of death in the United States, affecting one in 10 people over the age of 65. Scientists are engineering nanodevices to disrupt processes in the brain that lead to the disease.

30 Apr 2020

UK-based biotechnology firm discovers potential treatments for Covid-19

A UK-based biotechnology firm has announced the discovery of two separate novel treatments for Covid-19 patients before they are put on ventilators. They are now urgently seeking funding of £4m to accelerate safety studies and clinical trials.

30 Apr 2020

Innovative STM method may lead to new, purer pharmaceuticals

A research project led by chemists at the University of Warwick first used ultrahigh resolution scanning tunnelling microscopy to see the exact location of atoms and bonds within a molecule, and then employed these incredibly precise images to determine the interactions that bond molecules to one another.

30 Apr 2020

Newly launched clinical trial can help treat COVID-19 patients

Research by University of Iowa virologist Wendy Maury, PhD, has helped facilitate the launch of a new clinical trial in the United Kingdom of a drug that might help treat patients with COVID-19.

30 Apr 2020

Tobacco smoking identified as a potential risk factor for COVID-19 infection

Researchers at Baylor College of Medicine, the University of South Carolina and other institutions have identified tobacco smoking as a potential risk factor for infection of the COVID-19 virus.

29 Apr 2020

KU Leuven study uncovers how signaling molecule plays key role in learning process

Neurobiologists at KU Leuven have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process.

29 Apr 2020

Low levels of vitamin D may be linked to severe COVID-19

A new observational study from the United States indicates that vitamin D insufficiency may play a significant role in the progression of coronavirus disease (COVID-19). The research titled 'Vitamin D Insufficiency is Prevalent in Severe COVID-19' is available on the preprint server medRxiv.Study shows that low levels of vitamin D may be linked to severe COVID-19

29 Apr 2020

Study explores molecular connections between genetics, gut microbiome and memory

A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population.

29 Apr 2020

Researchers develop a gentler and safer hair dye based on synthetic melanin

With the coronavirus pandemic temporarily shuttering hair salons, many clients are appreciating, and missing, the ability of hair dye to cover up grays or touch up roots.

29 Apr 2020

Study reveals SARS-CoV-2 RNA cap structure

A new study published on the preprint server bioRxiv in April 2020 reports the discovery of the structure of the cap created by the novel coronavirus on virally encoded mRNAs. The finding could help create new antiviral strategies.

29 Apr 2020

Epivax and Entos Pharmaceuticals to develop DNA-based vaccine for COVID-19

Entos Pharmaceuticals (Entos), a healthcare biotechnology company that develops next generation nucleic acid medicines using the Fusogenix drug delivery platform, today announced a collaboration with EpiVax, Inc. (EpiVax), a world leading informatics and immunology biotechnology company with a proven track record in vaccine development.

28 Apr 2020