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Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

In a new study, researchers determined if the higher transmission rate of the SARS-CoV-2 Omicron variant is due to a higher viral load compared to the Delta variant.

8 Feb 2022

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

In a recent research article published in the journal of Science Immunology, a team of researchers from Japan performed longitudinal analysis on the cellular composition of receptor-binding domain (RBD) memory B cell subsets and its antibody binding and neutralizing activity against the Beta, Delta, and Omicron variants following the second dose of a messenger ribonucleic acid (mRNA) vaccine.

8 Feb 2022

SARS-CoV-2 infection-induced antibodies may last more than 20 months

A recent research letter published in the JAMA demonstrated the prevalence and the longevity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) unvaccinated United States (US) adults recovered from the disease in the long term.

7 Feb 2022

Study shows chronic alcohol consumption as a potential risk factor for SARS-CoV-2-infection

In a study posted to the bioRxiv* preprint server, a team of researchers from Germany studied the expression data of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-relevant genes such as angiotensin-converting enzyme 2 (ACE2), transmembrane serine protease 2 (TMPRSS2), and the G-protein coupled receptor Mas in an alcohol-exposed rodent model infected with SARS-CoV-2.

7 Feb 2022

Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

Researchers validate a quick, highly efficient, and automated assay to detect neutralizing antibodies against SARS-CoV-2.

7 Feb 2022

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Scientists recently evaluated the effectiveness of a booster dose of the Moderna-developed COVID-19 vaccine and omicron spike-specific mRNA vaccine in non-human primates that are primed with the Moderna vaccine.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Researchers have been investigating sarbecovirus lineages and the ability of those lineages to evolve the ability to bind ACE2.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

In a new study, researchers investigated a link between the body’s inflammatory response to SARS-CoV-2 infection within the neuropathological pathways and tau hyperphosphorylation.

7 Feb 2022

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Researchers conducted an observational study to compare the humoral and cellular responses in health care workers who had received two doses of the Pfizer-BioNTech vaccine at standard (3 to 6 weeks) and delayed (8 to 16 week) intervals.

7 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

mRNA booster vaccination shown to induce robust neutralizing antibodies against SARS-CoV-2 omicron variant

Scientists recently assessed the immunogenicity of a third booster dose of COVID-19 vaccines against SARS-CoV-2 variants.

4 Feb 2022

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

In a new study, a team of researchers developed a hybrid vaccine for SARS-CoV-2 and influenza viruses using influenza virus-like particles (VLP).

4 Feb 2022

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

In a new study, researchers showed that 425 nm blue light can inactivate all major SARS CoV 2 variants.

4 Feb 2022

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Researchers aimed to understand the relationship between the SARS-CoV-2 receptor-binding domain and both human receptors and therapeutic targets.

3 Feb 2022

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Researchers evaluate how the D614G and P681H mutations alter the attributes of SARS-CoV-2 VOCs.

3 Feb 2022

Better diagnostic tests needed to guide HER2 breast cancer treatment, study suggests

A new study by researchers at Yale Cancer Center shows using current standard human epidermal growth factor receptor 2 (HER2) assays as a diagnostic test may result in a mis-assignment of patients for treatment for breast cancer with a promising new drug.

3 Feb 2022

Scientists identify genome regions linked to migraine risk

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine.

3 Feb 2022

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

A central feature of type 1 diabetes is loss of the pancreatic beta cells that make insulin. Researchers led by Paolo Fiorina, MD, PhD, of Boston Children's Hospital and Francesca D'Addio, MD, of the University of Milan now identify a harmful cellular pathway that causes these cells to die.

3 Feb 2022

Receptor News and Research

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

SARS-CoV-2 infection-induced antibodies may last more than 20 months

Study shows chronic alcohol consumption as a potential risk factor for SARS-CoV-2-infection

Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Investigating the immunology of COVID-19 infected children

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

mRNA booster vaccination shown to induce robust neutralizing antibodies against SARS-CoV-2 omicron variant

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Better diagnostic tests needed to guide HER2 breast cancer treatment, study suggests

Scientists identify genome regions linked to migraine risk

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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