Therapy News and Research

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Addition of torcetrapib to statin therapy has no benefit for atherosclerosis progression

For some patients with high cholesterol, even the most aggressive treatment with statin drugs fails to prevent coronary artery disease.

2 Apr 2007

Clinical trial of Ranibizumab for edema of the mAcula in diabetes

The Juvenile Diabetes Research Foundation, the world's largest charitable funder of type 1 diabetes research, announced that the Ranibizumab for Edema of the mAcula in Diabetes Phase 2 Study (READ 2) is now enrolling patients.

2 Apr 2007

Biopsy may underestimate prostate cancer in overweight men

Obese and overweight men who are diagnosed with prostate cancer by biopsy are more likely than healthy weight men to actually have a more aggressive case of the disease than the biopsy results would indicate, according to a study led by a Duke University Medical Center researcher.

2 Apr 2007

Adding estradiol to a polymer-free rapamycin-eluting stent is not associated with any measurable benefit

Patients admitted to the hospital with acute coronary syndromes (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention (PCI), during which a stent is inserted into an occluded or narrowed coronary artery to restore blood flow to and from the heart.

2 Apr 2007

Critical receptor in liver regeneration identified

In studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that a cellular receptor involved in triggering cell death is also a necessary component of tissue repair and regeneration immediately following liver injury.

2 Apr 2007

Triple negative breast cancers more common among women who are African American and Hispanic, under 40 years old

So-called "triple negative" breast cancers, tumors that do not contain any of three significant tumor markers, are aggressive, deadly cancers that affect young, poor minority women, according to a new study.

2 Apr 2007

Synthetic molecule helps detect heart attack in the making

A new bright spot in heart disease research may soon allow physicians to peer directly into patients' blood vessels and find dangerous cholesterol-filled plaques before they rupture and cause a heart attack.

2 Apr 2007

Long-term low to moderate doses of aspirin beneficial for women

Women who take low to moderate doses of aspirin have a reduced risk of death from any cause, and especially heart disease related deaths, according to a report in the March 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

2 Apr 2007

Lack of Olig1 protein in lung tumors may increase risk of death

A study of human lung tumors indicates that lung cancer patients who lack a particular protein may do more poorly than those with normal levels of that same protein.

2 Apr 2007

Costs due to complications from preterm birth are staggering

In Canada, outlays for specialized care of surviving preterm infants are estimated to be almost $2 billion per year.

2 Apr 2007

Breakthrough research finds genes which may help smoking cessation

Scientists supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, have for the first time identified genes that might increase a person's ability to abstain from smoking.

2 Apr 2007

New screening method for cervical cancer holds promise

A method of screening women in Ghana for early signs of cervical cancer and providing preventive treatment at the same visit appears to be safe, acceptable to women and feasible, according to a study by a researcher at the Stanford University School of Medicine.

2 Apr 2007

Treatment for acute intermittent porphyria

The Center for Applied Medical Research (CIMA) from the University of Navarra and the Amsterdam Molecular Therapeutics BV (AMT) have demonstrated the pre-clinical effectiveness of a treatment against acute intermittent porphyria.

2 Apr 2007

Traumatic memories can be wiped out

French CNRS scientists in collaboration have shown that a memory of a traumatic event can be wiped out, although other, associated recollections remain intact.

2 Apr 2007

Study results on bifeprunox in patients with schizophrenia

Solvay Pharmaceuticals, Inc., Wyeth Pharmaceuticals and Lundbeck A/S presented clinical study results on bifeprunox at an international medical congress this week.

2 Apr 2007

Multiple sclerosis patients need better socio-economic support

People with multiple sclerosis need much more practical help and better care support, according to a study published in the latest Journal of Advanced Nursing.

2 Apr 2007

Actigraphy helps assess and manage sleep disorders

Actigraphy, the use of a portable device that records movement over extended periods of time, and has been used extensively in the study of sleep and circadian rhythms, provides an acceptably accurate estimate of sleep patterns in normal, healthy adult populations and in-patients suspected of certain sleep disorders, according to practice parameters published in the April 1st issue of the journal SLEEP.

2 Apr 2007

Iron nanoparticles exhibit toxic effects on neuronal cells

Researchers at UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applications can be toxic to nerve cells and interfere with the formation of their signal-transmitting extensions.

1 Apr 2007

Coronary procedure adds no benefit over 'optimal medical therapy' alone

Percutaneous coronary intervention plus optimal medical therapy does not improve outcomes in patients with coronary artery disease, compared with optimal medical therapy alone, according to study results presented at the 56th Annual Scientific Session of the American College of Cardiology in New Orleans, and published online in the New England Journal of Medicine.

1 Apr 2007

Bone marrow stem cells used to regenerate healthy human liver tissue

For the first time, researchers have used adult bone marrow stem cells to regenerate healthy human liver tissue, according to a study published in the April issue of the journal Radiology.

1 Apr 2007